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Department of Genetics and Tumor Cell Biology
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top-articles
Department of Genetics and Tumor Cell Biology
171
(top 1%)
papers
16.7K
(top 1%)
citations
73
(top 1%)
h
-index
128
(top 1%)
g
-index
175
all documents
17.8K
doc citations
2.3K
citing journals
Top Articles
#
Title
Journal
Year
Citations
1
Principles of Tumor Suppression
Cell
2004
850
2
The role of the unfolded protein response in tumour development: friend or foe?
Nature Reviews Cancer
2004
668
3
Lymphatic vascular defects promoted by Prox1 haploinsufficiency cause adult-onset obesity
Nature Genetics
2005
499
4
Six2 is required for suppression of nephrogenesis and progenitor renewal in the developing kidney
EMBO Journal
2006
431
5
Cyclin-dependent kinases: a family portrait
Nature Cell Biology
2009
381
6
Delineation of a Negative Feedback Regulatory Loop That Controls Protein Translation during Endoplasmic Reticulum Stress
Journal of Biological Chemistry
2003
380
7
ER chaperone functions during normal and stress conditions
Journal of Chemical Neuroanatomy
2004
365
8
The neurodegenerative disease protein aprataxin resolves abortive DNA ligation intermediates
Nature
2006
348
9
A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging
Nature Genetics
2009
317
10
ATM and ataxia telangiectasia
EMBO Reports
2004
314
11
Lymphatic endothelial cell identity is reversible and its maintenance requires Prox1 activity
Genes and Development
2008
289
12
Human Leukocyte Antigen-B-Associated Transcript 3 Is Released from Tumor Cells and Engages the NKp30 Receptor on Natural Killer Cells
Immunity
2007
284
13
Long-term Safety and Efficacy Following Systemic Administration of a Self-complementary AAV Vector Encoding Human FIX Pseudotyped With Serotype 5 and 8 Capsid Proteins
Molecular Therapy
2011
280
14
Nucleolar Arf Tumor Suppressor Inhibits Ribosomal RNA Processing
Molecular Cell
2003
267
15
GM1-Ganglioside Accumulation at the Mitochondria-Associated ER Membranes Links ER Stress to Ca2+-Dependent Mitochondrial Apoptosis
Molecular Cell
2009
257
16
Canonical Wnt9b signaling balances progenitor cell expansion and differentiation during kidney development
Development (Cambridge)
2011
254
17
DNA Strand Break Repair and Human Genetic Disease
Annual Review of Genomics and Human Genetics
2007
251
18
DNA Ligase III Promotes Alternative Nonhomologous End-Joining during Chromosomal Translocation Formation
PLoS Genetics
2011
250
19
The ER function BiP is a master regulator of ER function
Mount Sinai Journal of Medicine
2004
247
20
The nuclear hormone receptor Coup-TFII is required for the initiation and early maintenance of
Prox1
expression in lymphatic endothelial cells
Genes and Development
2010
243
21
Mutations in SIL1 cause Marinesco-Sjögren syndrome, a cerebellar ataxia with cataract and myopathy
Nature Genetics
2005
232
22
BRAF and FBXW7 (CDC4, FBW7, AGO, SEL10) Mutations in Distinct Subsets of Pancreatic Cancer
American Journal of Pathology
2003
225
23
An Unfolded CH1 Domain Controls the Assembly and Secretion of IgG Antibodies
Molecular Cell
2009
209
24
GM1-Ganglioside-Mediated Activation of the Unfolded Protein Response Causes Neuronal Death in a Neurodegenerative Gangliosidosis
Molecular Cell
2004
208
25
Loss of suppressor-of-fused function promotes tumorigenesis
Oncogene
2007
204
26
E3 Ubiquitin Ligases as Regulators of Membrane Protein Trafficking and Degradation
Traffic
2005
201
27
THE LYMPHATIC VASCULATURE: Recent Progress and Paradigms
Annual Review of Cell and Developmental Biology
2005
200
28
Characterization of an ERAD Pathway for Nonglycosylated BiP Substrates, which Require Herp
Molecular Cell
2007
193
29
Crucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repair
Nature
2011
190
30
N-terminal polyubiquitination and degradation of the Arf tumor suppressor
Genes and Development
2004
180
31
Progressive hearing loss in mice lacking the cyclin-dependent kinase inhibitor Ink4d
Nature Cell Biology
2003
178
32
Selective utilization of nonhomologous end-joining and homologous recombination DNA repair pathways during nervous system development
Proceedings of the National Academy of Sciences of the United States of America
2006
168
33
Haploinsufficiency of Six3 Fails to Activate Sonic hedgehog Expression in the Ventral Forebrain and Causes Holoprosencephaly
Developmental Cell
2008
160
34
Plasticity of Button-Like Junctions in the Endothelium of Airway Lymphatics in Development and Inflammation
American Journal of Pathology
2012
154
35
Role of CDK/cyclin complexes in transcription and RNA splicing
Cellular Signalling
2005
153
36
Disulfide bonds in ER protein folding and homeostasis
Current Opinion in Cell Biology
2011
150
37
Six3 activation of Pax6 expression is essential for mammalian lens induction and specification
EMBO Journal
2006
147
38
Crystal Structure of Human Vinculin
Structure
2004
146
39
Current views on the function of the lymphatic vasculature in health and disease
Genes and Development
2010
145
40
Herp Is Dually Regulated by Both the Endoplasmic Reticulum Stress-specific Branch of the Unfolded Protein Response and a Branch That Is Shared with Other Cellular Stress Pathways
Journal of Biological Chemistry
2004
141
41
The concerted activities of Pax4 and Nkx2.2 are essential to initiate pancreatic β-cell differentiation
Developmental Biology
2004
141
42
Prox1 expression patterns in the developing and adult murine brain
Developmental Dynamics
2007
138
43
Neuraminidase 1 Is a Negative Regulator of Lysosomal Exocytosis
Developmental Cell
2008
136
44
Transcription Factor Glis3, a Novel Critical Player in the Regulation of Pancreatic β-Cell Development and Insulin Gene Expression
Molecular and Cellular Biology
2009
133
45
ASAP, a Novel Protein Complex Involved in RNA Processing and Apoptosis
Molecular and Cellular Biology
2003
131
46
CDK11 Complexes Promote Pre-mRNA Splicing
Journal of Biological Chemistry
2003
131
47
A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8
Nature Structural and Molecular Biology
2004
128
48
Endothelial cell plasticity: how to become and remain a lymphatic endothelial cell
Development (Cambridge)
2010
126
49
Oxidative Folding: Cellular Strategies for Dealing with the Resultant Equimolar Production of Reactive Oxygen Species
Antioxidants and Redox Signaling
2009
124
50
Regulated association of misfolded endoplasmic reticulum lumenal proteins with P58/DNAJc3
EMBO Journal
2008
122
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