| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 | Cell Death and Differentiation | 2018 | 4,036 |
| 3 | How regulatory T cells work | Nature Reviews Immunology | 2008 | 2,638 |
| 4 | Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009 | Cell Death and Differentiation | 2009 | 2,572 |
| 5 | Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012 | Cell Death and Differentiation | 2012 | 2,144 |
| 6 | Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection | Nature Immunology | 2009 | 1,754 |
| 7 | The Transcription Factor Myc Controls Metabolic Reprogramming upon T Lymphocyte Activation | Immunity | 2011 | 1,698 |
| 8 | The inhibitory cytokine IL-35 contributes to regulatory T-cell function | Nature | 2007 | 1,678 |
| 9 | HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells | Journal of Experimental Medicine | 2011 | 1,447 |
| 10 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 11 | Immune Inhibitory Molecules LAG-3 and PD-1 Synergistically Regulate T-cell Function to Promote Tumoral Immune Escape | Cancer Research | 2012 | 1,311 |
| 12 | The BCL-2 Family Reunion | Molecular Cell | 2010 | 1,295 |
| 13 | Molecular definitions of autophagy and related processes | EMBO Journal | 2017 | 1,230 |
| 14 | Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted State6 gene | Nature | 1996 | 1,223 |
| 15 | Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases | Immunological Reviews | 2017 | 1,104 |
| 16 | Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells | Nature | 1996 | 1,059 |
| 17 | Catalytic activity of the caspase-8–FLIPL complex inhibits RIPK3-dependent necrosis | Nature | 2011 | 1,059 |
| 18 | Correction of multi-gene deficiency in vivo using a single 'self-cleaving' 2A peptide–based retroviral vector | Nature Biotechnology | 2004 | 1,051 |
| 19 | Role of LAG-3 in Regulatory T Cells | Immunity | 2004 | 1,040 |
| 20 | IL-12 family cytokines: immunological playmakers | Nature Immunology | 2012 | 1,001 |
| 21 | Chemical Inhibition of the Mitochondrial Division Dynamin Reveals Its Role in Bax/Bak-Dependent Mitochondrial Outer Membrane Permeabilization | Developmental Cell | 2008 | 992 |
| 22 | Mitochondria and the Autophagy–Inflammation–Cell Death Axis in Organismal Aging | Science | 2011 | 983 |
| 23 | Immunogenic and tolerogenic cell death | Nature Reviews Immunology | 2009 | 970 |
| 24 | Cytoplasmic functions of the tumour suppressor p53 | Nature | 2009 | 965 |
| 25 | Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes | Cell | 2021 | 923 |
| 26 | Defining ‘T cell exhaustion’ | Nature Reviews Immunology | 2019 | 879 |
| 27 | Cytochrome c: functions beyond respiration | Nature Reviews Molecular Cell Biology | 2008 | 875 |
| 28 | Multiplexed particle-based flow cytometric assays | Journal of Immunological Methods | 2000 | 852 |
| 29 | The NLRP3 Inflammasome Protects against Loss of Epithelial Integrity and Mortality during Experimental Colitis | Immunity | 2010 | 830 |
| 30 | Cell Death Signaling | Cold Spring Harbor Perspectives in Biology | 2015 | 822 |
| 31 | Regulation of inflammasome activation | Immunological Reviews | 2015 | 813 |
| 32 | Synchronized renal tubular cell death involves ferroptosis | Proceedings of the National Academy of Sciences of the United States of America | 2014 | 801 |
| 33 | Regulation and function of mTOR signalling in T cell fate decisions | Nature Reviews Immunology | 2012 | 789 |
| 34 | X-linked anhidrotic ectodermal dysplasia with immunodeficiency is caused by impaired NF-κB signaling | Nature Genetics | 2001 | 784 |
| 35 | Glycogen Synthase Kinase-3 Regulates Mitochondrial Outer Membrane Permeabilization and Apoptosis by Destabilization of MCL-1 | Molecular Cell | 2006 | 759 |
| 36 | IL-35-mediated induction of a potent regulatory T cell population | Nature Immunology | 2010 | 731 |
| 37 | Quantifiable predictive features define epitope-specific T cell receptor repertoires | Nature | 2017 | 723 |
| 38 | Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins | Nature Cell Biology | 2015 | 702 |
| 39 | Necroptosis in development, inflammation and disease | Nature Reviews Molecular Cell Biology | 2017 | 687 |
| 40 | mTORC1 couples immune signals and metabolic programming to establish Treg-cell function | Nature | 2013 | 645 |
| 41 | Virus-Specific CD8+ T Cells in Primary and Secondary Influenza Pneumonia | Immunity | 1998 | 641 |
| 42 | The Intracellular Sensor NLRP3 Mediates Key Innate and Healing Responses to Influenza A Virus via the Regulation of Caspase-1 | Immunity | 2009 | 640 |
| 43 | Defective Lymphoid Development in Mice Lacking Jak3 | Science | 1995 | 620 |
| 44 | Autophagy in major human diseases | EMBO Journal | 2021 | 615 |
| 45 | Dynamic regulatory network controlling TH17 cell differentiation | Nature | 2013 | 608 |
| 46 | Autophagy-Independent Functions of the Autophagy Machinery | Cell | 2019 | 591 |
| 47 | Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 585 |
| 48 | TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection | Nature | 2019 | 581 |
| 49 | CD95 Signaling via Ceramide-rich Membrane Rafts | Journal of Biological Chemistry | 2001 | 559 |
| 50 | C11orf95–RELA fusions drive oncogenic NF-κB signalling in ependymoma | Nature | 2014 | 559 |
