| # | Title | Journal | Year | Citations |
|---|
| 1 | Tumour exosome integrins determine organotropic metastasis | Nature | 2015 | 3,688 |
| 2 | Natural engineering principles of electron tunnelling in biological oxidation–reduction | Nature | 1999 | 3,387 |
| 3 | Nature of biological electron transfer | Nature | 1992 | 1,853 |
| 4 | Primary structure effects on peptide group hydrogen exchange | Proteins: Structure, Function and Bioinformatics | 1993 | 1,805 |
| 5 | The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate | Cancer Cell | 2010 | 1,754 |
| 6 | Protein Phase Separation: A New Phase in Cell Biology | Trends in Cell Biology | 2018 | 1,439 |
| 7 | Comparing Photosynthetic and Photovoltaic Efficiencies and Recognizing the Potential for Improvement | Science | 2011 | 1,369 |
| 8 | Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS | Nature | 2013 | 1,249 |
| 9 | Towards a general theory of adaptive walks on rugged landscapes | Journal of Theoretical Biology | 1987 | 1,127 |
| 10 | Inhibition of PRC2 Activity by a Gain-of-Function H3 Mutation Found in Pediatric Glioblastoma | Science | 2013 | 1,074 |
| 11 | Protein folding intermediates: native-state hydrogen exchange | Science | 1995 | 1,056 |
| 12 | Direct measurement of local oxygen concentration in the bone marrow of live animals | Nature | 2014 | 933 |
| 13 | Structural characterization of folding intermediates in cytochrome c by H-exchange labelling and proton NMR | Nature | 1988 | 914 |
| 14 | Foldamers as versatile frameworks for the design and evolution of function | Nature Chemical Biology | 2007 | 839 |
| 15 | Crystal Structure of the Lactose Operon Repressor and Its Complexes with DNA and Inducer | Science | 1996 | 755 |
| 16 | 3D domain swapping: A mechanism for oligomer assembly | Protein Science | 1995 | 742 |
| 17 | Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers | Cell | 2020 | 691 |
| 18 | Correlation Between Intraluminal Oxygen Gradient and Radial Partitioning of Intestinal Microbiota | Gastroenterology | 2014 | 658 |
| 19 | Autocatalytic sets of proteins | Journal of Theoretical Biology | 1986 | 645 |
| 20 | A Lesson in Metabolic Regulation Inspired by the Glucokinase Glucose Sensor Paradigm | Diabetes | 1996 | 640 |
| 21 | Self-assembly of amphiphilic dendritic dipeptides into helical pores | Nature | 2004 | 613 |
| 22 | Conformational entropy in molecular recognition by proteins | Nature | 2007 | 604 |
| 23 | Design and synthesis of multi-haem proteins | Nature | 1994 | 592 |
| 24 | Centromere-Specific Assembly of CENP-A Nucleosomes Is Mediated by HJURP | Cell | 2009 | 588 |
| 25 | How many human proteoforms are there? | Nature Chemical Biology | 2018 | 580 |
| 26 | Fluorescence Spectroscopy of Neoplastic and Non-Neoplastic Tissues | Neoplasia | 2000 | 572 |
| 27 | Structural basis for the function and inhibition of an influenza virus proton channel | Nature | 2008 | 549 |
| 28 | The molecular language of membraneless organelles | Journal of Biological Chemistry | 2019 | 515 |
| 29 | Neurodegenerative disease: models, mechanisms, and a new hope | DMM Disease Models and Mechanisms | 2017 | 508 |
| 30 | Photobiomodulation Directly Benefits Primary Neurons Functionally Inactivated by Toxins | Journal of Biological Chemistry | 2005 | 498 |
| 31 | Imaging of phosphorescence: a novel method for measuring oxygen distribution in perfused tissue | Science | 1988 | 487 |
| 32 | Correlated and uncorrelated fitness landscapes and how to tell the difference | Biological Cybernetics | 1990 | 468 |
| 33 | Biological selectivity and functional aspects of protein tyrosine nitration | Biochemical and Biophysical Research Communications | 2003 | 468 |
| 34 | Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments | Nature Methods | 2019 | 452 |
| 35 | Recovery from exercise-induced desaturation in the quadriceps muscles of elite competitive rowers | American Journal of Physiology - Cell Physiology | 1992 | 449 |
| 36 | Amphiphilic Polymethacrylate Derivatives as Antimicrobial Agents | Journal of the American Chemical Society | 2005 | 446 |
| 37 | Apoptosis induced by withdrawal of interleukin-3 (IL-3) from an IL-3-dependent hematopoietic cell line is associated with repartitioning of intracellular calcium and is blocked by enforced Bcl-2 oncoprotein production. | Journal of Biological Chemistry | 1993 | 435 |
| 38 | Two-photon high-resolution measurement of partial pressure of oxygen in cerebral vasculature and tissue | Nature Methods | 2010 | 415 |
| 39 | The barriers in protein folding | Nature Structural Biology | 1994 | 409 |
| 40 | Coevolution to the edge of chaos: Coupled fitness landscapes, poised states, and coevolutionary avalanches | Journal of Theoretical Biology | 1991 | 407 |
| 41 | Folding of helical membrane proteins: the role of polar, GxxxG-like and proline motifs | Current Opinion in Structural Biology | 2004 | 402 |
| 42 | Regulation of cellular energy metabolism | Journal of Membrane Biology | 1982 | 401 |
| 43 | Iron–sulfur clusters/semiquinones in Complex I | Biochimica Et Biophysica Acta - Bioenergetics | 1998 | 390 |
| 44 | Crystal Structure of Biotin Synthase, an S-Adenosylmethionine-Dependent Radical Enzyme | Science | 2004 | 390 |
| 45 | Protein Folding Studied Using Hydrogen-Exchange Labeling and Two-Dimensional NMR | Annual Review of Biophysics and Biomolecular Structure | 1992 | 387 |
| 46 | Entropy--enthalpy compensation: Fact or artifact? | Protein Science | 2001 | 384 |
| 47 | HEAT CAPACITY IN PROTEINS | Annual Review of Physical Chemistry | 2005 | 384 |
| 48 | Quantitation of time- and frequency-resolved optical spectra for the determination of tissue oxygenation | Analytical Biochemistry | 1991 | 381 |
| 49 | The zinc finger transcription factor Egr-1 is essential for and restricts differentiation along the macrophage lineage | Cell | 1993 | 380 |
| 50 | Cognition-activated low-frequency modulation of light absorption in human brain. | Proceedings of the National Academy of Sciences of the United States of America | 1993 | 380 |
