| # | Title | Journal | Year | Citations |
|---|
| 1 | Brown and beige fat: development, function and therapeutic potential | Nature Medicine | 2013 | 1,846 |
| 2 | IDH mutation impairs histone demethylation and results in a block to cell differentiation | Nature | 2012 | 1,693 |
| 3 | An operational definition of epigenetics: Figure 1. | Genes and Development | 2009 | 1,457 |
| 4 | The Combined Functions of Proapoptotic Bcl-2 Family Members Bak and Bax Are Essential for Normal Development of Multiple Tissues | Molecular Cell | 2000 | 1,303 |
| 5 | Highly Efficient miRNA-Mediated Reprogramming of Mouse and Human Somatic Cells to Pluripotency | Cell Stem Cell | 2011 | 1,121 |
| 6 | Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS | Nature | 2010 | 1,117 |
| 7 | Cytoplasmic chromatin triggers inflammation in senescence and cancer | Nature | 2017 | 851 |
| 8 | Facilitators and Impediments of the Pluripotency Reprogramming Factors' Initial Engagement with the Genome | Cell | 2012 | 789 |
| 9 | Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity | Nature | 2015 | 788 |
| 10 | Brown and Beige Fat: Physiological Roles beyond Heat Generation | Cell Metabolism | 2015 | 763 |
| 11 | Repair and Regeneration of the Respiratory System: Complexity, Plasticity, and Mechanisms of Lung Stem Cell Function | Cell Stem Cell | 2014 | 748 |
| 12 | A dermal niche for multipotent adult skin-derived precursor cells | Nature Cell Biology | 2004 | 692 |
| 13 | Ryanodine receptors of striated muscles: a complex channel capable of multiple interactions | Physiological Reviews | 1997 | 688 |
| 14 | Differential Effects of Culture on Imprinted H19 Expression in the Preimplantation Mouse Embryo1 | Biology of Reproduction | 2000 | 687 |
| 15 | Role of Formins in Actin Assembly: Nucleation and Barbed-End Association | Science | 2002 | 664 |
| 16 | Epigenetic Mechanisms of Longevity and Aging | Cell | 2016 | 649 |
| 17 | Interconversion Between Intestinal Stem Cell Populations in Distinct Niches | Science | 2011 | 638 |
| 18 | X-Inactivation, Imprinting, and Long Noncoding RNAs in Health and Disease | Cell | 2013 | 631 |
| 19 | Disruption of TET2 promotes the therapeutic efficacy of CD19-targeted T cells | Nature | 2018 | 574 |
| 20 | SAVER: gene expression recovery for single-cell RNA sequencing | Nature Methods | 2018 | 574 |
| 21 | Pioneer transcription factors in cell reprogramming | Genes and Development | 2014 | 541 |
| 22 | Shape, Size, and Distribution of Ca2+ Release Units and Couplons in Skeletal and Cardiac Muscles | Biophysical Journal | 1999 | 540 |
| 23 | Assembly dynamics of microtubules at molecular resolution | Nature | 2006 | 531 |
| 24 | Autophagy mediates degradation of nuclear lamina | Nature | 2015 | 510 |
| 25 | Control of brown and beige fat development | Nature Reviews Molecular Cell Biology | 2016 | 507 |
| 26 | Lung development: orchestrating the generation and regeneration of a complex organ | Development (Cambridge) | 2014 | 469 |
| 27 | CAR T cells produced in vivo to treat cardiac injury | Science | 2022 | 441 |
| 28 | Fibrin Formation, Structure and Properties | Sub-Cellular Biochemistry | 2017 | 434 |
| 29 | Mechanism of Ca2+ Disruption in Alzheimer's Disease by Presenilin Regulation of InsP3 Receptor Channel Gating | Neuron | 2008 | 426 |
| 30 | Targeting cardiac fibrosis with engineered T cells | Nature | 2019 | 404 |
| 31 | The p35/Cdk5 kinase is a neuron-specific Rac effector that inhibits Pak1 activity | Nature | 1998 | 380 |
| 32 | H3K9me3-Dependent Heterochromatin: Barrier to Cell Fate Changes | Trends in Genetics | 2016 | 380 |
| 33 | A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 375 |
| 34 | Mechanisms of fibrin polymerization and clinical implications | Blood | 2013 | 371 |
| 35 | Mapping the Pairwise Choices Leading from Pluripotency to Human Bone, Heart, and Other Mesoderm Cell Types | Cell | 2016 | 367 |
| 36 | A Microfabricated Platform to Measure and Manipulate the Mechanics of Engineered Cardiac Microtissues | Tissue Engineering - Part A | 2012 | 355 |
| 37 | Bone Regenerates via Dedifferentiation of Osteoblasts in the Zebrafish Fin | Developmental Cell | 2011 | 346 |
| 38 | Cohesins localize with CTCF at the KSHV latency control region and at cellular c-myc and H19/Igf2 insulators | EMBO Journal | 2008 | 326 |
| 39 | Pioneer transcription factors, chromatin dynamics, and cell fate control | Current Opinion in Genetics and Development | 2016 | 312 |
| 40 | Clot contraction: compression of erythrocytes into tightly packed polyhedra and redistribution of platelets and fibrin | Blood | 2014 | 311 |
| 41 | Genetic Analysis of Digestive Physiology Using Fluorescent Phospholipid Reporters | Science | 2001 | 308 |
| 42 | Transcriptional and DNA Binding Activity of the Foxp1/2/4 Family Is Modulated by Heterotypic and Homotypic Protein Interactions | Molecular and Cellular Biology | 2004 | 288 |
| 43 | An abundant erythroid protein that stabilizes free α-haemoglobin | Nature | 2002 | 287 |
| 44 | Zfh-1 Controls Somatic Stem Cell Self-Renewal in the Drosophila Testis and Nonautonomously Influences Germline Stem Cell Self-Renewal | Cell Stem Cell | 2008 | 280 |
| 45 | Controllable protein phase separation and modular recruitment to form responsive membraneless organelles | Nature Communications | 2018 | 274 |
| 46 | Loss of NAD Homeostasis Leads to Progressive and Reversible Degeneration of Skeletal Muscle | Cell Metabolism | 2016 | 273 |
| 47 | Computational Design of Peptides That Target Transmembrane Helices | Science | 2007 | 271 |
| 48 | Cholesterol Efflux-Mediated Signal Transduction in Mammalian Sperm: Cholesterol Release Signals an Increase in Protein Tyrosine Phosphorylation during Mouse Sperm Capacitation | Developmental Biology | 1999 | 256 |
| 49 | A Gata6-Wnt pathway required for epithelial stem cell development and airway regeneration | Nature Genetics | 2008 | 254 |
| 50 | Plasticity of Hopx+ type I alveolar cells to regenerate type II cells in the lung | Nature Communications | 2015 | 254 |
