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Top Articles

#TitleJournalYearCitations
1The Vast Majority of CLA+ T Cells Are Resident in Normal SkinJournal of Immunology2006674
2Autoantibodies against cardiac troponin I are responsible for dilated cardiomyopathy in PD-1-deficient miceNature Medicine2003606
3Engineering hybrid exosomes by membrane fusion with liposomesScientific Reports2016447
4Skin-specific expression of IL-33 activates group 2 innate lymphoid cells and elicits atopic dermatitis-like inflammation in miceProceedings of the National Academy of Sciences of the United States of America2013360
5Serum miR-200c Is a Novel Prognostic and Metastasis-Predictive Biomarker in Patients With Colorectal CancerAnnals of Surgery2014271
6A genome-wide association study identifies two novel susceptibility loci and trans population polygenicity associated with bipolar disorderMolecular Psychiatry2018159
7Threshold-like pattern of neuronal activation in the hypothalamus during treadmill running: Establishment of a minimum running stress (MRS) rat modelNeuroscience Research2007134
8Human Mast Cell Chymase Cleaves Pro-IL-18 and Generates a Novel and Biologically Active IL-18 FragmentJournal of Immunology2006123
9Report from the fourth international consensus meeting to harmonize core outcome measures for atopic eczema/dermatitis clinical trials (HOME initiative)British Journal of Dermatology2016115
10Tenascin C Induces Epithelial-Mesenchymal Transition–Like Change Accompanied by SRC Activation and Focal Adhesion Kinase Phosphorylation in Human Breast Cancer CellsAmerican Journal of Pathology2011114
11Granzyme B is a novel interleukin-18 converting enzymeJournal of Dermatological Science2010109
12Subcortical vascular dementiaNeuroscience Research2011109
13Deficiency of tenascin-C attenuates liver fibrosis in immune-mediated chronic hepatitis in miceJournal of Pathology2007106
14Neuromelanin Magnetic Resonance Imaging in Parkinson's Disease and Multiple System AtrophyEuropean Neurology2013106
15Current Venous Thromboembolism Management and Outcomes in JapanCirculation Journal2014106
16Toll-Like Receptor 4 Mediates Lung Ischemia-Reperfusion InjuryAnnals of Thoracic Surgery2006105
17Mitochondrial membrane potential and reactive oxygen species in cancer stem cellsFamilial Cancer2015105
18Genome-wide association study of panic disorder in the Japanese populationJournal of Human Genetics2009104
19Annual Change of Primary Resistance to Clarithromycin amongHelicobacter pyloriIsolates from 1996 through 2008 in JapanHelicobacter200994
20Antimicrobial Agent of Susceptibilities and Antiseptic Resistance Gene Distribution among Methicillin-Resistant Staphylococcus aureus Isolates from Patients with Impetigo and Staphylococcal Scalded Skin SyndromeJournal of Clinical Microbiology200688
21Calcineurin Inhibitors Suppress Cytokine Production from Memory T Cells and Differentiation of Naïve T Cells into Cytokine-Producing Mature T CellsPLoS ONE201287
22Transient responses of inflammatory cytokines in acute stressBiological Psychology200985
23Diagnostic Potential of Cell-Free and Exosomal MicroRNAs in the Identification of Patients with High-Risk Colorectal AdenomasPLoS ONE201683
24Co‐expression of hepatocyte growth factor and c‐Met predicts peritoneal dissemination established by autocrine hepatocyte growth factor/c‐Met signaling in gastric cancerInternational Journal of Cancer201281
25A RNA-Sequencing approach for the identification of novel long non-coding RNA biomarkers in colorectal cancerScientific Reports201880
26Oxidative DNA Damage in Relation to Neurotoxicity in the Brain of Mice Exposed to Arsenic at Environmentally Relevant LevelsJournal of Occupational Health200579
27Selective white matter abnormalities in a novel rat model of vascular dementiaNeurobiology of Aging201279
28Analyses of the MAPT, PGRN, and C9orf72 mutations in Japanese patients with FTLD, PSP, and CBSParkinsonism and Related Disorders201377
29Prevalence of anastomotic leak and the impact of indocyanine green fluorescein imaging for evaluating blood flow in the gastric conduit following esophageal cancer surgeryEsophagus201777
30Proteomic Profiling of Exosomal Proteins for Blood-based Biomarkers in Parkinson's DiseaseNeuroscience201876
31Nonexploratory movement and behavioral alterations in a thalidomide or valproic acid-induced autism model ratNeuroscience Research201074
32Replication and meta-analysis of TMEM132D gene variants in panic disorderTranslational Psychiatry201274
33Soluble PD-L1 Expression in Circulation as a Predictive Marker for Recurrence and Prognosis in Gastric Cancer: Direct Comparison of the Clinical Burden Between Tissue and Serum PD-L1 ExpressionAnnals of Surgical Oncology201974
34Involvement of Propionibacterium acnes in the Augmentation of Lipogenesis in Hamster Sebaceous Glands In Vivo and In VitroJournal of Investigative Dermatology200972
35Nardilysin regulates axonal maturation and myelination in the central and peripheral nervous systemNature Neuroscience200972
36VPS35 mutation in Japanese patients with typical Parkinson's diseaseMovement Disorders201270
37A Novel, Reliable Method for Repeated Blood Collection from Aquarium FishZebrafish201369
38The Influence of Chronic Cerebral Hypoperfusion on Cognitive Function and Amyloid β Metabolism in APP Overexpressing MicePLoS ONE201168
39Tenascin‐C enhances crosstalk signaling of integrin αvβ3/PDGFR‐β complex by SRC recruitment promoting PDGF‐induced proliferation and migration in smooth muscle cellsJournal of Cellular Physiology201168
40Midline Lumbar Fusion with Cortical Bone Trajectory ScrewNeurologia Medico-Chirurgica201468
41Thrombomodulin: A Bifunctional Modulator of Inflammation and Coagulation in SepsisCritical Care Research and Practice201266
42Genome-wide stability of the DNA replication program in single mammalian cellsNature Genetics201966
43IQGAPs as Key Regulators of Actin-cytoskeleton DynamicsCell Structure and Function201565
44Music Therapy Using Singing Training Improves Psychomotor Speed in Patients with Alzheimer's Disease: A Neuropsychological and fMRI StudyDementia and Geriatric Cognitive Disorders Extra201565
45Effects of quetiapine on monoamine, GABA, and glutamate release in rat prefrontal cortexPsychopharmacology200964
46The Effects of Physical Exercise with Music on Cognitive Function of Elderly People: Mihama-Kiho ProjectPLoS ONE201464
47ONO‐2506 inhibits spike–wave discharges in a genetic animal model without affecting traditional convulsive tests via gliotransmission regulationBritish Journal of Pharmacology201361
48MiR-139-5p as a novel serum biomarker for recurrence and metastasis in colorectal cancerScientific Reports201761
49Zonisamide enhances delta receptor-associated neurotransmitter release in striato-pallidal pathwayNeuropharmacology200959
50Meta-analysis of genome-wide association studies for panic disorder in the Japanese populationTranslational Psychiatry201259