| # | Title | Journal | Year | Citations |
|---|
| 1 | Linking Long-Term Dietary Patterns with Gut Microbial Enterotypes | Science | 2011 | 5,253 |
| 2 | Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis | Nature Medicine | 2013 | 3,355 |
| 3 | Sampling error and intraobserver variation in liver biopsy in patients with chronic HCV infection | American Journal of Gastroenterology | 2002 | 1,878 |
| 4 | Gut microbiota and IBD: causation or correlation? | Nature Reviews Gastroenterology and Hepatology | 2017 | 1,099 |
| 5 | The association between hepatitis C infection and survival after orthotopic liver transplantation | Gastroenterology | 2002 | 994 |
| 6 | ACG Clinical Guideline: Management of Crohn's Disease in Adults | American Journal of Gastroenterology | 2018 | 851 |
| 7 | Enterotypes in the landscape of gut microbial community composition | Nature Microbiology | 2018 | 717 |
| 8 | Correlation Between Intraluminal Oxygen Gradient and Radial Partitioning of Intestinal Microbiota | Gastroenterology | 2014 | 658 |
| 9 | Inflammation, Antibiotics, and Diet as Environmental Stressors of the Gut Microbiome in Pediatric Crohn’s Disease | Cell Host and Microbe | 2015 | 646 |
| 10 | Innate lymphoid cells regulate CD4+ T-cell responses to intestinal commensal bacteria | Nature | 2013 | 639 |
| 11 | Roles for Intestinal Bacteria, Viruses, and Fungi in Pathogenesis of Inflammatory Bowel Diseases and Therapeutic Approaches | Gastroenterology | 2017 | 615 |
| 12 | Lectin-type oxidized LDL receptor-1 distinguishes population of human polymorphonuclear myeloid-derived suppressor cells in cancer patients | Science Immunology | 2016 | 560 |
| 13 | Cdx1 and Cdx2 expression during intestinal development | Gastroenterology | 2000 | 556 |
| 14 | Rapid evolution of the human gut virome | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 489 |
| 15 | Changes in the Prevalence of Hepatitis C Virus Infection, Nonalcoholic Steatohepatitis, and Alcoholic Liver Disease Among Patients With Cirrhosis or Liver Failure on the Waitlist for Liver Transplantation | Gastroenterology | 2017 | 487 |
| 16 | Diet and the Intestinal Microbiome: Associations, Functions, and Implications for Health and Disease | Gastroenterology | 2014 | 486 |
| 17 | An Intestine-Specific Homeobox Gene Regulates Proliferation and Differentiation | Molecular and Cellular Biology | 1996 | 475 |
| 18 | Developing an instrument to assess the endoscopic severity of ulcerative colitis: the Ulcerative Colitis Endoscopic Index of Severity (UCEIS) | Gut | 2012 | 463 |
| 19 | Update on Fecal Microbiota Transplantation 2015: Indications, Methodologies, Mechanisms, and Outlook | Gastroenterology | 2015 | 460 |
| 20 | Comparative metabolomics in vegans and omnivores reveal constraints on diet-dependent gut microbiota metabolite production | Gut | 2016 | 428 |
| 21 | Bile Acid and Inflammation Activate Gastric Cardia Stem Cells in a Mouse Model of Barrett-Like Metaplasia | Cancer Cell | 2012 | 395 |
| 22 | The Proinflammatory Mediators C3a and C5a Are Essential for Liver Regeneration | Journal of Experimental Medicine | 2003 | 385 |
| 23 | ACG Clinical Guideline: Preventive Care in Inflammatory Bowel Disease | American Journal of Gastroenterology | 2017 | 364 |
| 24 | Second infections independently increase mortality in hospitalized patients With cirrhosis: the north american consortium for the study of end-stage liver disease (NACSELD) experience | Hepatology | 2012 | 357 |
| 25 | AGA Clinical Practice Guidelines on the Management of Moderate to Severe Ulcerative Colitis | Gastroenterology | 2020 | 355 |
| 26 | Reliability and Initial Validation of the Ulcerative Colitis Endoscopic Index of Severity | Gastroenterology | 2013 | 354 |
| 27 | Thymic stromal lymphopoietin–elicited basophil responses promote eosinophilic esophagitis | Nature Medicine | 2013 | 351 |
| 28 | Group 3 Innate Lymphoid Cells Inhibit T-Cell-Mediated Intestinal Inflammation through Aryl Hydrocarbon Receptor Signaling and Regulation of Microflora | Immunity | 2013 | 343 |
| 29 | AGA Institute Rapid Review of the Gastrointestinal and Liver Manifestations of COVID-19, Meta-Analysis of International Data, and Recommendations for the Consultative Management of Patients with COVID-19 | Gastroenterology | 2020 | 330 |
| 30 | Risk of Lymphoma in Patients With Inflammatory Bowel Disease Treated With Azathioprine and 6-Mercaptopurine: A Meta-analysis | Clinical Gastroenterology and Hepatology | 2015 | 322 |
| 31 | Diet in the Pathogenesis and Treatment of Inflammatory Bowel Diseases | Gastroenterology | 2015 | 311 |
| 32 | Control of cell morphology and differentiation by substrates with independently tunable elasticity and viscous dissipation | Nature Communications | 2018 | 301 |
| 33 | Effect of Once- or Twice-Daily MMX Mesalamine (SPD476) for the Induction of Remission of Mild to Moderately Active Ulcerative Colitis | Clinical Gastroenterology and Hepatology | 2007 | 264 |
| 34 | Effectiveness of screening colonoscopy in reducing the risk of death from right and left colon cancer: a large community-based study | Gut | 2018 | 264 |
| 35 | Remission in Patients with Crohn's Disease is Associated with Improvement in Employment and Quality of Life and a Decrease in Hospitalizations and Surgeries | American Journal of Gastroenterology | 2004 | 257 |
| 36 | AGA Rapid Recommendations for Gastrointestinal Procedures During the COVID-19 Pandemic | Gastroenterology | 2020 | 254 |
| 37 | Expression of intestine‐specific transcription factors, CDX1 and CDX2, in intestinal metaplasia and gastric carcinomas | Journal of Pathology | 2003 | 248 |
| 38 | Structure and Distribution of an Unrecognized Interstitium in Human Tissues | Scientific Reports | 2018 | 243 |
| 39 | Virus-helminth coinfection reveals a microbiota-independent mechanism of immunomodulation | Science | 2014 | 238 |
| 40 | The tumor microenvironment in esophageal cancer | Oncogene | 2016 | 234 |
| 41 | Outcomes of EMR of defiant colorectal lesions directed to an endoscopy referral center | Gastrointestinal Endoscopy | 2012 | 231 |
| 42 | The IL-27 Receptor (WSX-1) Is an Inhibitor of Innate and Adaptive Elements of Type 2 Immunity | Journal of Immunology | 2004 | 226 |
| 43 | Hepatocyte Nuclear Factor-1α, GATA-4, and Caudal Related Homeodomain Protein Cdx2 Interact Functionally to Modulate Intestinal Gene Transcription | Journal of Biological Chemistry | 2002 | 221 |
| 44 | The role of Cdx proteins in intestinal development and cancer | Cancer Biology and Therapy | 2004 | 219 |
| 45 | Alcohol-induced generation of lipid peroxidation products in humans | Journal of Clinical Investigation | 1999 | 216 |
| 46 | Histone deacetylase 3 coordinates commensal-bacteria-dependent intestinal homeostasis | Nature | 2013 | 212 |
| 47 | Successful Treatment of Hepatitis C in Renal Transplant Recipients With Direct-Acting Antiviral Agents | American Journal of Transplantation | 2016 | 201 |
| 48 | Suppression of HCV-specific T cells without differential hierarchy demonstrated in persistent HCV infection | Hepatology | 2003 | 199 |
| 49 | Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition | Nature Medicine | 2018 | 196 |
| 50 | Hepatic Fibrosis Is Universal Following Fontan Operation, and Severity is Associated With Time From Surgery: A Liver Biopsy and Hemodynamic Study | Journal of the American Heart Association | 2017 | 195 |
