| # | Title | Journal | Year | Citations |
|---|
| 1 | Antiobesity effects of Kaempferia parviflora in spontaneously obese type II diabetic mice | Journal of Natural Medicines | 2011 | 79 |
| 2 | Chlorella variabilis and Micractinium reisseri sp. nov. (Chlorellaceae, Trebouxiophyceae): Redescription of the endosymbiotic green algae of Paramecium bursaria (Peniculia, Oligohymenophorea) in the 120th year | Phycological Research | 2010 | 77 |
| 3 | All-atom molecular dynamics calculation study of entire poliovirus empty capsids in solution | Journal of Chemical Physics | 2014 | 69 |
| 4 | Simvastatin and atorvastatin facilitates amyloid β‐protein degradation in extracellular spaces by increasing neprilysin secretion from astrocytes through activation of MAPK/Erk1/2 pathways | Glia | 2016 | 60 |
| 5 | The Critical Role of Passive Permeability in Designing Successful Drugs | ChemMedChem | 2020 | 53 |
| 6 | Citrus nobiletin suppresses inducible nitric oxide synthase gene expression in interleukin-1β-treated hepatocytes | Biochemical and Biophysical Research Communications | 2013 | 47 |
| 7 | The constituents of licorice (Glycyrrhiza uralensis) differentially suppress nitric oxide production in interleukin-1β-treated hepatocytes | Biochemistry and Biophysics Reports | 2015 | 46 |
| 8 | Surface-induced phase separation of a sphingomyelin/cholesterol/ganglioside GM1-planar bilayer on mica surfaces and microdomain molecular conformation that accelerates Aβ oligomerization | Biochimica Et Biophysica Acta - Biomembranes | 2010 | 45 |
| 9 | Insulin-signaling Pathway Regulates the Degradation of Amyloid β-protein via Astrocytes | Neuroscience | 2018 | 44 |
| 10 | Brain insulin resistance accelerates Aβ fibrillogenesis by inducing GM1 ganglioside clustering in the presynaptic membranes | Journal of Neurochemistry | 2012 | 43 |
| 11 | Gomisin N in the herbal drug gomishi (Schisandra chinensis) suppresses inducible nitric oxide synthase gene via C/EBPβ and NF-κB in rat hepatocytes | Nitric Oxide - Biology and Chemistry | 2013 | 41 |
| 12 | Identification of anti-inflammatory constituents in Phellodendri Cortex and Coptidis Rhizoma by monitoring the suppression of nitric oxide production | Journal of Natural Medicines | 2017 | 40 |
| 13 | Preventive effect of Kaempferia parviflora ethyl acetate extract and its major components polymethoxyflavonoid on metabolic diseases | Fìtoterapìâ | 2011 | 38 |
| 14 | Stabilization of human interferon-α1 mRNA by its antisense RNA | Cellular and Molecular Life Sciences | 2013 | 34 |
| 15 | A new flavanone and other flavonoids from green perilla leaf extract inhibit nitric oxide production in interleukin 1β-treated hepatocytes | Bioscience, Biotechnology and Biochemistry | 2015 | 33 |
| 16 | Crystal growth kinetics and morphology of isotactic polybutene-1 trigonal phase in the melt | Journal of Crystal Growth | 2009 | 27 |
| 17 | Cyclin-Dependent Kinase-Like 5 (CDKL5): Possible Cellular Signalling Targets and Involvement in CDKL5 Deficiency Disorder | Neural Plasticity | 2020 | 26 |
| 18 | Leptin inhibits amyloid β-protein degradation through decrease of neprilysin expression in primary cultured astrocytes | Biochemical and Biophysical Research Communications | 2014 | 25 |
| 19 | HDAC8 regulates neural differentiation through embryoid body formation in P19 cells | Biochemical and Biophysical Research Communications | 2018 | 25 |
| 20 | Regulatory non-coding RNAs in nervous system development and disease | Frontiers in Bioscience - Landmark | 2019 | 25 |
| 21 | An FT-IR Study on Packing Defects in Mixed β-Aggregates of Poly(l-glutamic acid) and Poly(d-glutamic acid): A High-Pressure Rescue from a Kinetic Trap | Journal of Physical Chemistry B | 2012 | 23 |
| 22 | Ketamine reduces amyloid β-protein degradation by suppressing neprilysin expression in primary cultured astrocytes | Neuroscience Letters | 2013 | 23 |
| 23 | Interaction Site between the Protein Aggregates and Thiocyanate Ion in Aqueous Solution: A Case Study of 1-Butyl-3-methylimidazolium Thiocyanate | Journal of Physical Chemistry B | 2015 | 22 |
| 24 | Propofol and Thiopental Suppress Amyloid Fibril Formation and GM1 Ganglioside Expression through the γ-Aminobutyric Acid A Receptor | Anesthesiology | 2013 | 20 |
| 25 | Leptin inhibits amyloid β‐protein fibrillogenesis by decreasing GM1 gangliosides on the neuronal cell surface through PI3K/Akt/mTOR pathway | Journal of Neurochemistry | 2014 | 20 |
| 26 | Rationale and design of Diabetes Prevention with active Vitamin D (DPVD): a randomised, double-blind, placebo-controlled study | BMJ Open | 2016 | 20 |
| 27 | Direct observation of minimum‐sized amyloid fibrils using solution NMR spectroscopy | Protein Science | 2010 | 19 |
| 28 | Direct electrochemical analyses of human cytochromes b5 with a mutated heme pocket showed a good correlation between their midpoint and half wave potentials | Journal of Biomedical Science | 2010 | 18 |
| 29 | Interferon-alpha competing endogenous RNA network antagonizes microRNA-1270 | Cellular and Molecular Life Sciences | 2015 | 17 |
| 30 | Phylogenetically Close Group I Introns with Different Positions among Paramecium bursaria Photobionts Imply a Primitive Stage of Intron Diversification | Molecular Biology and Evolution | 2009 | 16 |
| 31 | Midazolam inhibits the formation of amyloid fibrils and GM1 ganglioside-rich microdomains in presynaptic membranes through the gamma-aminobutyric acid A receptor | Biochemical and Biophysical Research Communications | 2015 | 15 |
| 32 | Melt Crystallization of isotactic Polybutene-1Trigonal Form: the Effect of Side Chain Entropy on Crystal Growth Kinetics | Polymer Journal | 2008 | 13 |
| 33 | Novel cis-active structures in the coding region mediate CRM1-dependent nuclear export of IFN-α 1 mRNA | Medical Molecular Morphology | 2010 | 13 |
| 34 | In Silico Study of Rett Syndrome Treatment-Related Genes, MECP2, CDKL5, and FOXG1, by Evolutionary Classification and Disordered Region Assessment | International Journal of Molecular Sciences | 2019 | 12 |
| 35 | Protein kinases A and C regulate amyloid-β degradation by modulating protein levels of neprilysin and insulin-degrading enzyme in astrocytes | Neuroscience Research | 2021 | 12 |
| 36 | Comparison Between Clopidogrel and Prasugrel Associated With <i>CYP2C19</i> Genotypes in Patients Receiving Percutaneous Coronary Intervention in a Japanese Population | Circulation Journal | 2020 | 12 |
| 37 | Nucleocytoplasmic transport of luciferase gene mRNA requires CRM1/Exportin1 and RanGTPase | Medical Molecular Morphology | 2009 | 11 |
| 38 | EPHA2 antisense RNA modulates EPHA2 mRNA levels in basal-like/triple-negative breast cancer cells | Biochimie | 2020 | 11 |
| 39 | Melt growth rate and growth shape of Isotactic polybutene-1 tetragonal crystals | Journal of Crystal Growth | 2009 | 10 |
| 40 | Insulin inhibits Aβ fibrillogenesis through a decrease of the GM1 ganglioside‐rich microdomain in neuronal membranes | Journal of Neurochemistry | 2010 | 10 |
| 41 | Incidence of Type 2 Diabetes in Pre-Diabetic Japanese Individuals Categorized by HbA1c Levels: A Historical Cohort Study | PLoS ONE | 2015 | 10 |
| 42 | Induction of Maltose Release by Light in the Endosymbiont Chlorella variabilis of Paramecium bursaria | Protist | 2016 | 10 |
| 43 | Potential mechanisms underlying embryonic developmental toxicity caused by benzo[a]pyrene in Japanese medaka (Oryzias latipes) | Chemosphere | 2020 | 10 |
| 44 | Functional expression and characterization of human 101F6 protein, a homologue of cytochrome b561 and a candidate tumor suppressor gene product | BioFactors | 2008 | 9 |
| 45 | Differences in the Structural Stability and Cooperativity between Monomeric Variants of Natural and de Novo Cro Proteins Revealed by High-Pressure Fourier Transform Infrared Spectroscopy | Biochemistry | 2012 | 9 |
| 46 | Cytological, genetic, and biochemical characteristics of an unusual non‐Chlorella photobiont of Stentor polymorphus collected from an artificial pond close to the shore of Lake Biwa, Japan | Phycological Research | 2013 | 9 |
| 47 | A novel CDKL5 mutation in a Japanese patient with atypical Rett syndrome | Clinica Chimica Acta | 2016 | 9 |
| 48 | Lignans from guaiac resin decrease nitric oxide production in interleukin 1β-treated hepatocytes | Journal of Natural Medicines | 2017 | 9 |
| 49 | Effect of Atorvastatin and Etidronate Combination Therapy on Regression of Aortic Atherosclerotic Plaques Evaluated by Magnetic Resonance Imaging | Journal of Atherosclerosis and Thrombosis | 2011 | 9 |
| 50 | The σ1 receptor regulates accumulation of GM1 ganglioside-enriched autophagosomes in astrocytes | Neuroscience | 2017 | 8 |
