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Top Articles

#TitleJournalYearCitations
12015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid CancerThyroid201610,674
2Analysis of protein-coding genetic variation in 60,706 humansNature20169,051
3Surviving Sepsis CampaignCritical Care Medicine20136,362
4Linking Long-Term Dietary Patterns with Gut Microbial EnterotypesScience20115,253
5Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)Autophagy20164,701
6Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteriaLancet Neurology, The20184,605
7Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock, 2012Intensive Care Medicine20133,906
8Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's diseaseNature Genetics20133,741
9Tumour exosome integrins determine organotropic metastasisNature20153,688
10Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic LeukemiaNew England Journal of Medicine20183,680
11Genetic effects on gene expression across human tissuesNature20173,500
12Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosisNature Medicine20133,355
13Guidelines for the use and interpretation of assays for monitoring autophagyAutophagy20123,122
14Chimeric Antigen Receptor–Modified T Cells in Chronic Lymphoid LeukemiaNew England Journal of Medicine20113,067
15MYC on the Path to CancerCell20122,577
16Antimicrobial Autophagy: A Conserved Innate Immune Response in DrosophilaJournal of Innate Immunity20132,441
17A refined compilation of implementation strategies: results from the Expert Recommendations for Implementing Change (ERIC) projectImplementation Science20152,295
18Prediction models for diagnosis and prognosis of covid-19: systematic review and critical appraisalBMJ, The20202,134
19Intestinal epithelial cells: regulators of barrier function and immune homeostasisNature Reviews Immunology20142,123
20Innate lymphoid cells — a proposal for uniform nomenclatureNature Reviews Immunology20132,054
21A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery diseaseNature Genetics20152,054
22Guidelines of the American Thyroid Association for the Diagnosis and Management of Thyroid Disease During Pregnancy and PostpartumThyroid20112,014
23Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancerNature20151,955
24Predicting the Future — Big Data, Machine Learning, and Clinical MedicineNew England Journal of Medicine20161,955
25Cytokine StormNew England Journal of Medicine20201,911
26Brown and beige fat: development, function and therapeutic potentialNature Medicine20131,846
27Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 responseNature20181,836
282017 Guidelines of the American Thyroid Association for the Diagnosis and Management of Thyroid Disease During Pregnancy and the PostpartumThyroid20171,811
29A circadian gene expression atlas in mammals: Implications for biology and medicineProceedings of the National Academy of Sciences of the United States of America20141,802
30ASTCT Consensus Grading for Cytokine Release Syndrome and Neurologic Toxicity Associated with Immune Effector CellsBiology of Blood and Marrow Transplantation20191,741
31Geroscience: Linking Aging to Chronic DiseaseCell20141,709
32IDH mutation impairs histone demethylation and results in a block to cell differentiationNature20121,693
33Stromal Elements Act to Restrain, Rather Than Support, Pancreatic Ductal AdenocarcinomaCancer Cell20141,616
34Patterns and rates of exonic de novo mutations in autism spectrum disordersNature20121,597
35Advancing The Cancer Genome Atlas glioma MRI collections with expert segmentation labels and radiomic featuresScientific Data20171,555
36European Position Paper on Rhinosinusitis and Nasal Polyps 2020Rhinology20201,555
37The Human Cell AtlasELife20171,547
38The social motivation theory of autismTrends in Cognitive Sciences20121,474
39Large-scale association analysis identifies new risk loci for coronary artery diseaseNature Genetics20131,439
40Protein Phase Separation: A New Phase in Cell BiologyTrends in Cell Biology20181,439
41Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1Autophagy20211,430
42Revision and Update of the Consensus Definitions of Invasive Fungal Disease From the European Organization for Research and Treatment of Cancer and the Mycoses Study Group Education and Research ConsortiumClinical Infectious Diseases20201,429
43Clinical diagnosis of progressive supranuclear palsy: The movement disorder society criteriaMovement Disorders20171,402
44Opportunities and obstacles for deep learning in biology and medicineJournal of the Royal Society Interface20181,282
45A compendium of RNA-binding motifs for decoding gene regulationNature20131,281
46T-cell invigoration to tumour burden ratio associated with anti-PD-1 responseNature20171,280
47Guidelines on the Use of Therapeutic Apheresis in Clinical Practice – Evidence‐Based Approach from the Writing Committee of the American Society for Apheresis: The Eighth Special IssueJournal of Clinical Apheresis20191,263
48SIRT1 Is Required for AMPK Activation and the Beneficial Effects of Resveratrol on Mitochondrial FunctionCell Metabolism20121,251
49Efficacy and safety of voretigene neparvovec (AAV2-hRPE65v2) in patients with RPE65 -mediated inherited retinal dystrophy: a randomised, controlled, open-label, phase 3 trialLancet, The20171,250
50Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALSNature20131,249