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Top Articles

#TitleJournalYearCitations
1Neutrophils and immunity: challenges and opportunitiesNature Reviews Immunology20062,394
2Nonresolving InflammationCell20101,717
3Transcriptional Adaptation of Mycobacterium tuberculosis within MacrophagesJournal of Experimental Medicine20031,311
4Beyond oxidative stress: an immunologist's guide to reactive oxygen speciesNature Reviews Immunology20131,181
5Mechanisms of Coronavirus Cell Entry Mediated by the Viral Spike ProteinViruses20121,086
6Activation of the SARS coronavirus spike protein via sequential proteolytic cleavage at two distinct sitesProceedings of the National Academy of Sciences of the United States of America2009906
7Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesityNature2015788
8Innate lymphoid cells as regulators of immunity, inflammation and tissue homeostasisNature Immunology2016760
9Host cell proteases: Critical determinants of coronavirus tropism and pathogenesisVirus Research2015752
10Foamy macrophages and the progression of the human tuberculosis granulomaNature Immunology2009673
11Regulation and Function of T-Cell-Mediated Immunity duringToxoplasma gondiiInfectionClinical Microbiology Reviews1998648
12Coronavirus membrane fusion mechanism offers a potential target for antiviral developmentAntiviral Research2020635
13Host cell entry of Middle East respiratory syndrome coronavirus after two-step, furin-mediated activation of the spike proteinProceedings of the National Academy of Sciences of the United States of America2014576
14Who puts the tubercle in tuberculosis?Nature Reviews Microbiology2007540
15Loss of ATRX, Genome Instability, and an Altered DNA Damage Response Are Hallmarks of the Alternative Lengthening of Telomeres PathwayPLoS Genetics2012489
16The neuropeptide NMU amplifies ILC2-driven allergic lung inflammationNature2017460
17β-Coronaviruses Use Lysosomes for Egress Instead of the Biosynthetic Secretory PathwayCell2020441
18Reprogramming of the Macrophage Transcriptome in Response to Interferon-γ and Mycobacterium tuberculosisJournal of Experimental Medicine2001437
19Dissecting virus entry via endocytosisJournal of General Virology2002433
20Tuberculosis: What We Don’t Know Can, and Does, Hurt UsScience2010430
21Emerging Functions of Amphiregulin in Orchestrating Immunity, Inflammation, and Tissue RepairImmunity2015429
22Stabilization of the Soluble, Cleaved, Trimeric Form of the Envelope Glycoprotein Complex of Human Immunodeficiency Virus Type 1Journal of Virology2002424
23Group 3 innate lymphoid cells mediate intestinal selection of commensal bacteria–specific CD4 + T cellsScience2015421
24Growth of Mycobacterium tuberculosis in vivo segregates with host macrophage metabolism and ontogenyJournal of Experimental Medicine2018421
25Caseation of human tuberculosis granulomas correlates with elevated host lipid metabolismEMBO Molecular Medicine2010417
26IL-33 promotes an innate immune pathway of intestinal tissue protection dependent on amphiregulin–EGFR interactionsProceedings of the National Academy of Sciences of the United States of America2015407
27The neuropeptide neuromedin U stimulates innate lymphoid cells and type 2 inflammationNature2017400
28A Review of the Progress and Challenges of Developing a Vaccine for COVID-19Frontiers in Immunology2020384
29Immune Regulation of Metabolic Homeostasis in Health and DiseaseCell2015380
30Metabolic Enzymes of Mycobacteria Linked to Antioxidant Defense by a Thioredoxin-Like ProteinScience2002378
31Intracellular Mycobacterium tuberculosis Exploits Host-derived Fatty Acids to Limit Metabolic StressJournal of Biological Chemistry2013352
32Mycobacterium tuberculosis Invasion of Macrophages: Linking Bacterial Gene Expression to Environmental CuesCell Host and Microbe2007344
33Marek's disease virus: from miasma to modelNature Reviews Microbiology2006343
34Ultrastructural Localization of the Herpes Simplex Virus Type 1 U L 31, U L 34, and U S 3 Proteins Suggests Specific Roles in Primary Envelopment and Egress of NucleocapsidsJournal of Virology2002318
35Impairment of Tetanus Toxoid-Specific Thl-like Immune Responses in Humans Infected with Schistosoma mansoniJournal of Infectious Diseases1996317
36Mycobacterium tuberculosis and the environment within the phagosomeImmunological Reviews2007314
37Lysosomal killing of Mycobacterium mediated by ubiquitin-derived peptides is enhanced by autophagyProceedings of the National Academy of Sciences of the United States of America2007305
38Isolation of Mycobacterium tuberculosis mutants defective in the arrest of phagosome maturationProceedings of the National Academy of Sciences of the United States of America2004291
39Protozoan encounters with Toll-like receptor signalling pathways: implications for host parasitismNature Reviews Immunology2006288
40Influenza Virus Can Enter and Infect Cells in the Absence of Clathrin-Mediated EndocytosisJournal of Virology2002286
41Microbial tryptophan metabolites regulate gut barrier function via the aryl hydrocarbon receptorProceedings of the National Academy of Sciences of the United States of America2020278
42U L 31 and U L 34 Proteins of Herpes Simplex Virus Type 1 Form a Complex That Accumulates at the Nuclear Rim and Is Required for Envelopment of NucleocapsidsJournal of Virology2001277
43CD8− Dendritic Cell Activation Status Plays an Integral Role in Influencing Th2 Response DevelopmentJournal of Immunology2001269
44Cross-Talk in the Innate Immune System: Neutrophils Instruct Recruitment and Activation of Dendritic Cells during Microbial InfectionJournal of Immunology2003262
45β 2 -adrenergic receptor–mediated negative regulation of group 2 innate lymphoid cell responsesScience2018262
46Inhibition of the B7-H3 immune checkpoint limits tumor growth by enhancing cytotoxic lymphocyte functionCell Research2017259
47Evolutionary Basis of Codon Usage and Nucleotide Composition Bias in Vertebrate DNA VirusesJournal of Molecular Evolution2006256
48MARCO, TLR2, and CD14 Are Required for Macrophage Cytokine Responses to Mycobacterial Trehalose Dimycolate and Mycobacterium tuberculosisPLoS Pathogens2009256
49Non-alcoholic fatty liver disease induces signs of Alzheimer’s disease (AD) in wild-type mice and accelerates pathological signs of AD in an AD modelJournal of Neuroinflammation2016254
50Physiological and molecular triggers for SARS-CoV membrane fusion and entry into host cellsVirology2018251