| # | Title | Journal | Year | Citations |
|---|
| 1 | Worldwide access to treatment for end-stage kidney disease: a systematic review | Lancet, The | 2015 | 1,522 |
| 2 | Low-density lipoproteins cause atherosclerotic cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus statement from the European Atherosclerosis Society Consensus Panel | European Heart Journal | 2020 | 776 |
| 3 | Social media and vaccine hesitancy: new updates for the era of COVID-19 and globalized infectious diseases | Human Vaccines and Immunotherapeutics | 2020 | 722 |
| 4 | Gait and Cognition: A Complementary Approach to Understanding Brain Function and the Risk of Falling | Journal of the American Geriatrics Society | 2012 | 703 |
| 5 | Shift work and vascular events: systematic review and meta-analysis | BMJ, The | 2012 | 595 |
| 6 | Drug treatments for covid-19: living systematic review and network meta-analysis | BMJ, The | 2020 | 592 |
| 7 | Hypertension Canada’s 2018 Guidelines for Diagnosis, Risk Assessment, Prevention, and Treatment of Hypertension in Adults and Children | Canadian Journal of Cardiology | 2018 | 474 |
| 8 | The polygenic nature of hypertriglyceridaemia: implications for definition, diagnosis, and management | Lancet Diabetes and Endocrinology,the | 2014 | 473 |
| 9 | Thrombosis risk associated with COVID-19 infection. A scoping review | Thrombosis Research | 2020 | 308 |
| 10 | Clinical review on triglycerides | European Heart Journal | 2020 | 286 |
| 11 | Hypertension Canada's 2017 Guidelines for Diagnosis, Risk Assessment, Prevention, and Treatment of Hypertension in Adults | Canadian Journal of Cardiology | 2017 | 269 |
| 12 | Chylomicronaemia—current diagnosis and future therapies | Nature Reviews Endocrinology | 2015 | 242 |
| 13 | Functional and Exercise Limitations After a First Episode of Pulmonary Embolism | Chest | 2017 | 192 |
| 14 | Converging Goals of Treatment of Inflammatory Bowel Disease From Clinical Trials and Practice | Gastroenterology | 2015 | 185 |
| 15 | Transporters in Drug Development: 2018 ITC Recommendations for Transporters of Emerging Clinical Importance | Clinical Pharmacology and Therapeutics | 2018 | 185 |
| 16 | RIPK3-Mediated Necroptosis Promotes Donor Kidney Inflammatory Injury and Reduces Allograft Survival | American Journal of Transplantation | 2013 | 181 |
| 17 | Living kidney donation: outcomes, ethics, and uncertainty | Lancet, The | 2015 | 174 |
| 18 | Evaluating patients' unmet needs in hidradenitis suppurativa: Results from the Global Survey Of Impact and Healthcare Needs (VOICE) Project | Journal of the American Academy of Dermatology | 2020 | 165 |
| 19 | The 2013 Canadian Hypertension Education Program Recommendations for Blood Pressure Measurement, Diagnosis, Assessment of Risk, Prevention, and Treatment of Hypertension | Canadian Journal of Cardiology | 2013 | 163 |
| 20 | Prothrombin Complex Concentrate for Major Bleeding on Factor Xa Inhibitors: A Prospective Cohort Study | Thrombosis and Haemostasis | 2018 | 157 |
| 21 | IOIBD technical review on endoscopic indices for Crohn's disease clinical trials | Gut | 2016 | 155 |
| 22 | Necroptosis in Immunity and Ischemia-Reperfusion Injury | American Journal of Transplantation | 2013 | 150 |
| 23 | Unilateral cortical FLAIR-hyperintense Lesions in Anti-MOG-associated Encephalitis with Seizures (FLAMES): characterization of a distinct clinico-radiographic syndrome | Journal of Neurology | 2019 | 145 |
| 24 | Urinary Biomarkers of AKI and Mortality 3 Years after Cardiac Surgery | Journal of the American Society of Nephrology: JASN | 2014 | 144 |
| 25 | Plasma IL-6 and IL-10 Concentrations Predict AKI and Long-Term Mortality in Adults after Cardiac Surgery | Journal of the American Society of Nephrology: JASN | 2015 | 144 |
| 26 | Hair cortisol analysis: An update on methodological considerations and clinical applications | Clinical Biochemistry | 2019 | 143 |
| 27 | Aldosterone mediates its rapid effects in vascular endothelial cells through GPER activation | American Journal of Physiology - Cell Physiology | 2013 | 141 |
| 28 | Advanced chronic kidney disease populations have elevated trimethylamine N-oxide levels associated with increased cardiovascular events | Kidney International | 2016 | 139 |
| 29 | Les canules nasales à haut débit pour le traitement de l’insuffisance respiratoire hypoxémique aiguë chez les patients atteints de la COVID-19: comptes rendus systématiques de l’efficacité et des risques d’aérosolisation, de dispersion et de transmission de l’infection | Canadian Journal of Anaesthesia | 2020 | 139 |
| 30 | Systematic review of prediction models for delirium in the older adult inpatient | BMJ Open | 2018 | 137 |
| 31 | Restrictive versus liberal blood transfusion for gastrointestinal bleeding: a systematic review and meta-analysis of randomised controlled trials | The Lancet Gastroenterology and Hepatology | 2017 | 131 |
| 32 | Detecting chronic kidney disease in population-based administrative databases using an algorithm of hospital encounter and physician claim codes | BMC Nephrology | 2013 | 128 |
| 33 | Comparison of Patient Survival Between Hemodialysis and Peritoneal Dialysis Among Patients Eligible for Both Modalities | American Journal of Kidney Diseases | 2018 | 126 |
| 34 | Calcium-Channel Blocker–Clarithromycin Drug Interactions and Acute Kidney Injury | JAMA - Journal of the American Medical Association | 2013 | 122 |
| 35 | Sitagliptin in patients with non-alcoholic steatohepatitis: A randomized, placebo-controlled trial | World Journal of Gastroenterology | 2017 | 121 |
| 36 | Comparative efficacy and safety of biologic therapies for moderate-to-severe Crohn's disease: a systematic review and network meta-analysis | The Lancet Gastroenterology and Hepatology | 2021 | 114 |
| 37 | Narrow-Band Imaging for Detection of Neoplasia at Colonoscopy: A Meta-analysis of Data From Individual Patients in Randomized Controlled Trials | Gastroenterology | 2019 | 113 |
| 38 | Kidney Outcomes 5 Years After Pediatric Cardiac Surgery | JAMA Pediatrics | 2016 | 112 |
| 39 | Derivation and External Validation of Prediction Models for Advanced Chronic Kidney Disease Following Acute Kidney Injury | JAMA - Journal of the American Medical Association | 2017 | 112 |
| 40 | The International/Canadian Hereditary Angioedema Guideline | Allergy, Asthma and Clinical Immunology | 2019 | 112 |
| 41 | Secular trends in acute dialysis after elective major surgery — 1995 to 2009 | Cmaj | 2012 | 111 |
| 42 | Secular Trends in Ischemic Stroke Subtypes and Stroke Risk Factors | Stroke | 2014 | 111 |
| 43 | A Modern Approach to Dyslipidemia | Endocrine Reviews | 2022 | 110 |
| 44 | Macrolide antibiotics and the risk of ventricular arrhythmia in older adults | Cmaj | 2016 | 109 |
| 45 | Hypertriglyceridemia | Nutrients | 2013 | 108 |
| 46 | Quality of Life, Dyspnea, and Functional Exercise Capacity Following a First Episode of Pulmonary Embolism: Results of the ELOPE Cohort Study | American Journal of Medicine | 2017 | 107 |
| 47 | Associations of Deceased Donor Kidney Injury With Kidney Discard and Function After Transplantation | American Journal of Transplantation | 2015 | 106 |
| 48 | Validity of theInternational Classification of Diseases, Tenth Revisioncode for acute kidney injury in elderly patients at presentation to the emergency department and at hospital admission | BMJ Open | 2012 | 103 |
| 49 | Histologic Evaluation of Ulcerative Colitis | Inflammatory Bowel Diseases | 2014 | 102 |
| 50 | Incremental Benefit of Achieving Endoscopic and Histologic Remission in Patients With Ulcerative Colitis: A Systematic Review and Meta-Analysis | Gastroenterology | 2020 | 101 |
