| # | Title | Journal | Year | Citations |
|---|
| 1 | Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps | Nature Genetics | 2018 | 1,331 |
| 2 | An atlas of genetic influences on human blood metabolites | Nature Genetics | 2014 | 1,084 |
| 3 | The UK10K project identifies rare variants in health and disease | Nature | 2015 | 1,014 |
| 4 | The genetic architecture of type 2 diabetes | Nature | 2016 | 952 |
| 5 | Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index | Nature Genetics | 2015 | 709 |
| 6 | Identification of region-specific astrocyte subtypes at single cell resolution | Nature Communications | 2020 | 444 |
| 7 | Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes | Nature Genetics | 2018 | 356 |
| 8 | Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis | PLoS Medicine | 2017 | 341 |
| 9 | The trans-ancestral genomic architecture of glycemic traits | Nature Genetics | 2021 | 341 |
| 10 | Single Cell Genomics: Advances and Future Perspectives | PLoS Genetics | 2014 | 337 |
| 11 | Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders | American Journal of Human Genetics | 2018 | 326 |
| 12 | Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets | Nature Genetics | 2017 | 257 |
| 13 | Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation | Nature Genetics | 2022 | 250 |
| 14 | Metabonomic, transcriptomic, and genomic variation of a population cohort | Molecular Systems Biology | 2010 | 230 |
| 15 | Genomics of disease risk in globally diverse populations | Nature Reviews Genetics | 2019 | 217 |
| 16 | Uric Acid and Cardiovascular Events | Journal of the American Society of Nephrology: JASN | 2015 | 216 |
| 17 | Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits | Nature Communications | 2017 | 169 |
| 18 | Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults | PLoS Genetics | 2017 | 158 |
| 19 | Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes | Nature Genetics | 2018 | 156 |
| 20 | Whole-genome sequencing of a sporadic primary immunodeficiency cohort | Nature | 2020 | 148 |
| 21 | Meta-Analysis of Genome-Wide Association Studies Identifies Six New Loci for Serum Calcium Concentrations | PLoS Genetics | 2013 | 142 |
| 22 | Diagnostic value of H3F3A mutations in giant cell tumour of bone compared to osteoclast‐rich mimics | Journal of Pathology: Clinical Research | 2015 | 135 |
| 23 | An Immune Response Network Associated with Blood Lipid Levels | PLoS Genetics | 2010 | 112 |
| 24 | A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip | Annals of the Rheumatic Diseases | 2014 | 108 |
| 25 | Incomplete genetic reconstitution of B cell pools contributes to prolonged immunosuppression after measles | Science Immunology | 2019 | 98 |
| 26 | Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types | Genome Biology | 2017 | 97 |
| 27 | Pain in 1,000 Women Treated for Breast Cancer | Anesthesiology | 2013 | 96 |
| 28 | A Comparison of the Whole Genome Approach of MeDIP-Seq to the Targeted Approach of the Infinium HumanMethylation450 BeadChip® for Methylome Profiling | PLoS ONE | 2012 | 83 |
| 29 | Analysis of deletion breakpoints from 1,092 humans reveals details of mutation mechanisms | Nature Communications | 2015 | 77 |
| 30 | The transferability of lipid loci across African, Asian and European cohorts | Nature Communications | 2019 | 75 |
| 31 | A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration | Human Molecular Genetics | 2016 | 73 |
| 32 | Estimating Genome‐Wide Significance for Whole‐Genome Sequencing Studies | Genetic Epidemiology | 2014 | 72 |
| 33 | Genetic Influences on Metabolite Levels: A Comparison across Metabolomic Platforms | PLoS ONE | 2016 | 69 |
| 34 | Very low-depth whole-genome sequencing in complex trait association studies | Bioinformatics | 2019 | 68 |
| 35 | A rare variant in APOC3 is associated with plasma triglyceride and VLDL levels in Europeans | Nature Communications | 2014 | 62 |
| 36 | Genetic characterization of Greek population isolates reveals strong genetic drift at missense and trait-associated variants | Nature Communications | 2014 | 60 |
| 37 | Advances in osteoarthritis genetics: Table 1 | Journal of Medical Genetics | 2013 | 51 |
| 38 | A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk | Diabetes | 2017 | 47 |
| 39 | Uncovering genetic mechanisms of hypertension through multi-omic analysis of the kidney | Nature Genetics | 2021 | 37 |
| 40 | Genetic predictors of risk and resilience in psychiatric disorders: A cross‐disorder genome‐wide association study of functional impairment in major depressive disorder, bipolar disorder, and schizophrenia | American Journal of Medical Genetics Part B: Neuropsychiatric Genetics | 2013 | 36 |
| 41 | Evidence for large-scale gene-by-smoking interaction effects on pulmonary function | International Journal of Epidemiology | 2017 | 36 |
| 42 | Maternal and fetal genetic contribution to gestational weight gain | International Journal of Obesity | 2018 | 36 |
| 43 | Associations Between Glycemic Traits and Colorectal Cancer: A Mendelian Randomization Analysis | Journal of the National Cancer Institute | 2022 | 35 |
| 44 | Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits | Nature Communications | 2018 | 33 |
| 45 | Investigation of common, low-frequency and rare genome-wide variation in anorexia nervosa | Molecular Psychiatry | 2018 | 32 |
| 46 | Sequence data and association statistics from 12,940 type 2 diabetes cases and controls | Scientific Data | 2017 | 31 |
| 47 | Discovery of novel heart rate-associated loci using the Exome Chip | Human Molecular Genetics | 2017 | 29 |
| 48 | Radiographic endophenotyping in hip osteoarthritis improves the precision of genetic association analysis | Annals of the Rheumatic Diseases | 2017 | 29 |
| 49 | Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study | PLoS ONE | 2017 | 29 |
| 50 | Transferability of genetic loci and polygenic scores for cardiometabolic traits in British Pakistani and Bangladeshi individuals | Nature Communications | 2022 | 29 |
