| # | Title | Journal | Year | Citations |
|---|
| 1 | Regulation and characteristics of vascular smooth muscle cell phenotypic diversity | Netherlands Heart Journal | 2007 | 734 |
| 2 | Clinical Expression of Leber Hereditary Optic Neuropathy Is Affected by the Mitochondrial DNA–Haplogroup Background | American Journal of Human Genetics | 2007 | 331 |
| 3 | Impact of maternal body mass index and gestational weight gain on pregnancy complications: an individual participant data meta‐analysis of European, North American and Australian cohorts | BJOG: an International Journal of Obstetrics and Gynaecology | 2019 | 327 |
| 4 | Identification of an X-Chromosomal Locus and Haplotype Modulating the Phenotype of a Mitochondrial DNA Disorder | American Journal of Human Genetics | 2005 | 181 |
| 5 | Polar body array CGH for prediction of the status of the corresponding oocyte. Part I: clinical results | Human Reproduction | 2011 | 179 |
| 6 | Multiple meiotic errors caused by predivision of chromatids in women of advanced maternal age undergoing in vitro fertilisation | European Journal of Human Genetics | 2012 | 155 |
| 7 | Development of burnout over time and the causal order of the three dimensions of burnout among male and female GPs. A three-wave panel study | BMC Public Health | 2011 | 147 |
| 8 | From fat to FAT (CD36/SR-B2): Understanding the regulation of cellular fatty acid uptake | Biochimie | 2017 | 146 |
| 9 | Variant CCG and GGC repeats within the CTG expansion dramatically modify mutational dynamics and likely contribute toward unusual symptoms in some myotonic dystrophy type 1 patients | Human Molecular Genetics | 2010 | 139 |
| 10 | Polar body array CGH for prediction of the status of the corresponding oocyte. Part II: technical aspects | Human Reproduction | 2011 | 130 |
| 11 | Influence of Mutation Type on Clinical Expression of Leber Hereditary Optic Neuropathy | American Journal of Ophthalmology | 2006 | 126 |
| 12 | Anthropometry, carbohydrate and lipid metabolism in the East Flanders Prospective Twin Survey: heritabilities | Diabetologia | 2007 | 124 |
| 13 | Theranostic USPIO‐Loaded Microbubbles for Mediating and Monitoring Blood‐Brain Barrier Permeation | Advanced Functional Materials | 2015 | 123 |
| 14 | Current issues in medically assisted reproduction and genetics in Europe: research, clinical practice, ethics, legal issues and policy | European Journal of Human Genetics | 2013 | 120 |
| 15 | Detection of chromosome aberrations in interphase tumor nuclei by nonradioactive in situ hybridization | Cancer Genetics and Cytogenetics | 1989 | 114 |
| 16 | Riboflavin-responsive oxidative phosphorylation complex I deficiency caused by defective ACAD9: new function for an old gene | Brain | 2011 | 113 |
| 17 | Health outcomes of children born after IVF/ICSI: a review of current expert opinion and literature | Reproductive BioMedicine Online | 2014 | 106 |
| 18 | A genetic variants database for arrhythmogenic right ventricular dysplasia/cardiomyopathy | Human Mutation | 2009 | 105 |
| 19 | Early-life exposome and lung function in children in Europe: an analysis of data from the longitudinal, population-based HELIX cohort | Lancet Planetary Health, The | 2019 | 100 |
| 20 | What next for preimplantation genetic screening? A polar body approach! | Human Reproduction | 2010 | 99 |
| 21 | Wnt5b stimulates adipogenesis by activating PPARγ, and inhibiting the β-catenin dependent Wnt signaling pathway together with Wnt5a | Biochemical and Biophysical Research Communications | 2009 | 92 |
| 22 | Good and bad consequences of altered fatty acid metabolism in heart failure: evidence from mouse models | Cardiovascular Research | 2015 | 78 |
| 23 | Preimplantation genetic diagnosis | Clinical Genetics | 2009 | 74 |
| 24 | Translocation 1;7 in hematologic disorders: A brief review of 22 cases | Cancer Genetics and Cytogenetics | 1985 | 72 |
| 25 | Cardiac Involvement in Adults With m.3243A>G MELAS Gene Mutation | American Journal of Cardiology | 2007 | 72 |
| 26 | Frequency of chest pain in primary care, diagnostic tests performed and final diagnoses | Heart | 2017 | 72 |
| 27 | Smoothelin-A Is Essential for Functional Intestinal Smooth Muscle Contractility in Mice | Gastroenterology | 2005 | 71 |
| 28 | Defective complex I assembly due to C20orf7 mutations as a new cause of Leigh syndrome | Journal of Medical Genetics | 2010 | 67 |
| 29 | Fruit consumption reduces the effect of smoking on bladder cancer risk. The Belgian case control study on bladder cancer | International Journal of Cancer | 2006 | 66 |
| 30 | Preadipocytes of type 2 diabetes subjects display an intrinsic gene expression profile of decreased differentiation capacity | International Journal of Obesity | 2011 | 66 |
| 31 | DNA Methylation Profiling of Uniparental Disomy Subjects Provides a Map of Parental Epigenetic Bias in the Human Genome | American Journal of Human Genetics | 2016 | 66 |
| 32 | Founder mutations among the Dutch | European Journal of Human Genetics | 2004 | 63 |
| 33 | Post-translational modifications of CD36 (SR-B2): Implications for regulation of myocellular fatty acid uptake | Biochimica Et Biophysica Acta - Molecular Basis of Disease | 2016 | 61 |
| 34 | Relation betweenChlamydia trachomatisinfection and pelvic inflammatory disease, ectopic pregnancy and tubal factor infertility in a Dutch cohort of women previously tested for chlamydia in a chlamydia screening trial | Sexually Transmitted Infections | 2019 | 60 |
| 35 | Current issues in medically assisted reproduction and genetics in Europe: research, clinical practice, ethics, legal issues and policy | Human Reproduction | 2014 | 57 |
| 36 | Human gametes and zygotes studied by nonradioactive in situ hybridization | Cytogenetic and Genome Research | 1990 | 56 |
| 37 | Novel Biomarkers to Improve the Prediction of Cardiovascular Event Risk in Type 2 Diabetes Mellitus | Journal of the American Heart Association | 2016 | 56 |
| 38 | Re-balancing cellular energy substrate metabolism to mend the failing heart | Biochimica Et Biophysica Acta - Molecular Basis of Disease | 2020 | 55 |
| 39 | Expression of the smoothelin gene is mediated by alternative promoters | Cardiovascular Research | 2002 | 54 |
| 40 | Twin-Specific Intrauterine ‘Growth’ Charts Based on Cross-Sectional Birthweight Data | Twin Research and Human Genetics | 2008 | 53 |
| 41 | Variable clinical manifestation of a novel missense mutation in the alpha-tropomyosin (TPM1) gene in familial hypertrophic cardiomyopathy | Journal of the American College of Cardiology | 2003 | 50 |
| 42 | Mutations in the ND5 subunit of complex I of the mitochondrial DNA are a frequent cause of oxidative phosphorylation disease | Journal of Medical Genetics | 2007 | 50 |
| 43 | Dealing with uncertainties: ethics of prenatal diagnosis and preimplantation genetic diagnosis to prevent mitochondrial disorders | Human Reproduction Update | 2008 | 49 |
| 44 | Early and transient gene expression changes in pressure overload-induced cardiac hypertrophy in mice | Genomics | 2006 | 48 |
| 45 | A MELAS-Associated ND1 Mutation Causing Leber Hereditary Optic Neuropathy and Spastic Dystonia | Archives of Neurology | 2007 | 48 |
| 46 | Yield of peripheral sodium channels gene screening in pure small fibre neuropathy | Journal of Neurology, Neurosurgery and Psychiatry | 2019 | 47 |
| 47 | Citation bias and other determinants of citation in biomedical research: findings from six citation networks | Journal of Clinical Epidemiology | 2021 | 47 |
| 48 | Cytogenetic analysis of in vitro fertilization (IVF) failures | Human Genetics | 1989 | 46 |
| 49 | Smoothelin-B Deficiency Results in Reduced Arterial Contractility, Hypertension, and Cardiac Hypertrophy in Mice | Circulation | 2008 | 46 |
| 50 | The transmission of OXPHOS disease and methods to prevent this | Human Reproduction Update | 2006 | 44 |
