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Top Articles

#TitleJournalYearCitations
1Comprehensive analysis of the chromatin landscape in Drosophila melanogasterNature2011781
2The 7SK small nuclear RNA inhibits the CDK9/cyclin T1 kinase to control transcriptionNature2001629
3Negative Feedback Regulation of TGF- Signaling by the SnoN OncoproteinScience1999480
4What can x-ray scattering tell us about the radial distribution functions of water?Journal of Chemical Physics2000381
5SPARX, a new environment for Cryo-EM image processingJournal of Structural Biology2007356
6TGF-β induces assembly of a Smad2–Smurf2 ubiquitin ligase complex that targets SnoN for degradationNature Cell Biology2001297
7The Dam1 kinetochore ring complex moves processively on depolymerizing microtubule endsNature2006260
8Ski and SnoN: negative regulators of TGF-β signalingCurrent Opinion in Genetics and Development2004206
9Structural Mechanism of Smad4 Recognition by the Nuclear Oncoprotein SkiCell2002200
10Smad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoNGenes and Development2001197
11Genome-wide analysis reveals a cell cycle–dependent mechanism controlling centromere propagationJournal of Cell Biology2008172
12Quercetin inhibits inducible ICAM-1 expression in human endothelial cells through the JNK pathwayAmerican Journal of Physiology - Cell Physiology1999170
13Mechanisms of photoswitch conjugation and light activation of an ionotropic glutamate receptorProceedings of the National Academy of Sciences of the United States of America2007169
14The Integral Inner Nuclear Membrane Protein MAN1 Physically Interacts with the R-Smad Proteins to Repress Signaling by the Transforming Growth Factor-β Superfamily of CytokinesJournal of Biological Chemistry2005154
15In Vivo Imaging of Caenorhabditis elegans GlycansACS Chemical Biology2009136
16The Crystal Structure of the Signal Recognition Particle in Complex with Its ReceptorScience2011132
17The Chromosome of Shigella flexneri Bacteriophage Sf6: Complete Nucleotide Sequence, Genetic Mosaicism, and DNA PackagingJournal of Molecular Biology2004131
18A Ras-induced conformational switch in the Ras activator Son of sevenlessProceedings of the National Academy of Sciences of the United States of America2006120
19Ski represses bone morphogenic protein signaling in Xenopus and mammalian cellsProceedings of the National Academy of Sciences of the United States of America2000117
20Cooperative Binding of Smad Proteins to Two Adjacent DNA Elements in the Plasminogen Activator Inhibitor-1 Promoter Mediates Transforming Growth Factor β-induced Smad-dependent Transcriptional ActivationJournal of Biological Chemistry1999116
21Nucleotide sequence of coliphage HK620 and the evolution of lambdoid phagesJournal of Molecular Biology2001116
22Identification of oligonucleotide sequences that direct the movement of the Escherichia coli FtsK translocaseProceedings of the National Academy of Sciences of the United States of America2005109
23Probing the Function of Heme Distortion in the H-NOX FamilyACS Chemical Biology2008108
24Reconstructing Voltage Sensor–Pore Interaction from a Fluorescence Scan of a Voltage-Gated K+ ChannelNeuron2000102
25Protein–protein interactions in the allosteric regulation of protein kinasesCurrent Opinion in Structural Biology200699
26Ultrafast Protein Dynamics of Bacteriorhodopsin Probed by Photon Echo and Transient Absorption SpectroscopyJournal of Physical Chemistry B200294
27Modulation of T cell signaling by the actin cytoskeletonJournal of Cell Science201390
28Clamp loaders and replication initiationCurrent Opinion in Structural Biology200688
29Cytological Analysis of Meiosis in Caenorhabditis elegansMethods in Molecular Biology200980
30Acetylation of Smad2 by the Co-activator p300 Regulates Activin and Transforming Growth Factor β ResponseJournal of Biological Chemistry200779
31A structural view of microtubule dynamicsCellular and Molecular Life Sciences199978
32The Cell Cycle Timing of Centromeric Chromatin Assembly in Drosophila Meiosis Is Distinct from Mitosis Yet Requires CAL1 and CENP-CPLoS Biology201272
33FBW7 Loss Promotes Chromosomal Instability and Tumorigenesis via Cyclin E1/CDK2–Mediated Phosphorylation of CENP-ACancer Research201768
34NO formation by a catalytically self-sufficient bacterial nitric oxide synthase from Sorangium cellulosumProceedings of the National Academy of Sciences of the United States of America200959
35Molecular MachinesJournal of Cell Biology200156
36Enrichment of HP1a on Drosophila Chromosome 4 Genes Creates an Alternate Chromatin Structure Critical for Regulation in this Heterochromatic DomainPLoS Genetics201248
37Structural Characterization of the L-to-M Transition of the Bacteriorhodopsin PhotocycleBiophysical Journal199841
38Nucleotide Regulation of Soluble Guanylate Cyclase Substrate SpecificityBiochemistry200937
39Tandem Histone Folds in the Structure of the N-Terminal Segment of the Ras Activator Son of SevenlessStructure200335
40Synthesis of Nitric Oxide by the NOS-like Protein from Deinococcus radiodurans: A Direct Role for TetrahydrofolateBiochemistry200934
41Structure and Properties of a Bis-Histidyl Ligated Globin from Caenorhabditis elegans,Biochemistry201032
42Pericentromeric heterochromatin is hierarchically organized and spatially contacts H3K9me2 islands in euchromatinPLoS Genetics202032
43Solution X-ray scattering as a probe of hydration-dependent structuring of aqueous solutionsJournal of Computer - Aided Molecular Design199930
44Rapid Evolution of Gained Essential Developmental Functions of a Young Gene via Interactions with Other Essential GenesMolecular Biology and Evolution201928
45Evolutionarily Conserved Roles of the Dicer Helicase Domain in Regulating RNA Interference ProcessingJournal of Biological Chemistry201417
46Phosphoregulation of DSB-1 mediates control of meiotic double-strand break activityELife016
47Representing and Reasoning about Protein Families Using Generative and Discriminative MethodsJournal of Computational Biology200010
48Structural and temporal regulation of centromeric chromatinThis paper is one of a selection of papers published in this Special Issue, entitled 29th Annual International Asilomar Chromatin and Chromosomes Conference, and has undergone the Journal’s usual peer review process.Biochemistry and Cell Biology20098
49Exploring the role of CENP-A Ser18 phosphorylation in CIN and TumorigenesisCell Cycle20176
50Origin of wiring specificity in an olfactory map revealed by neuron type–specific, time-lapse imaging of dendrite targetingELife03