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Top Articles

#TitleJournalYearCitations
1Synaptic plasticity and addictionNature Reviews Neuroscience20071,402
2Biologically erodable microspheres as potential oral drug delivery systemsNature1997808
3Recycling Endosomes Supply AMPA Receptors for LTPScience2004644
4Toxin-antitoxin systems in bacterial growth arrest and persistenceNature Chemical Biology2016579
5The extended PP1 toolkit: designed to create specificityTrends in Biochemical Sciences2010441
6Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule DynamicsMolecular Cell2017437
7Advances in the formation, use and understanding of multi-cellular spheroidsExpert Opinion on Biological Therapy2012413
8Mechanical stimulation improves tissue-engineered human skeletal muscleAmerican Journal of Physiology - Cell Physiology2002394
9Association between Plasma IL-6 Response to Acute Stress and Early-Life Adversity in Healthy AdultsNeuropsychopharmacology2010378
10TRPV1 Channels Mediate Long-Term Depression at Synapses on Hippocampal InterneuronsNeuron2008353
11Rapid Synaptic Plasticity of Glutamatergic Synapses on Dopamine Neurons in the Ventral Tegmental Area in Response to Acute Amphetamine InjectionNeuropsychopharmacology2004326
12Oral insulin delivery1Abbreviations: GI, gastrointestinal; IDDM, insulin-dependent diabetes mellitus; IU, international units; NIDDM, non-insulin-dependent diabetes mellitus; PIN, phase inversion nanoencapsulation; ZOT, zona occludens toxin.1Advanced Drug Delivery Reviews1999316
13Targeting the disordered C terminus of PTP1B with an allosteric inhibitorNature Chemical Biology2014294
14Opioids block long-term potentiation of inhibitory synapsesNature2007281
15A new type V toxin-antitoxin system where mRNA for toxin GhoT is cleaved by antitoxin GhoSNature Chemical Biology2012268
16Loci associated with skin pigmentation identified in African populationsScience2017260
17RGD-coated titanium implants stimulate increased bone formation in vivoBiomaterials1999259
18Nanosphere based oral insulin deliveryJournal of Controlled Release2000259
19SAP90 Binds and Clusters Kainate Receptors Causing Incomplete DesensitizationNeuron1998257
20Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple SitesCell2018253
21Molecular basis of MAP kinase regulationProtein Science2013241
22Hot flash: TRPV channels in the brainTrends in Neurosciences2009208
23Antitoxin MqsA helps mediate the bacterial general stress responseNature Chemical Biology2011201
24Structural basis for protein phosphatase 1 regulation and specificityFEBS Journal2013195
25SAP97 and CASK mediate sorting of NMDA receptors through a previously unknown secretory pathwayNature Neuroscience2009184
26Cellular mechanical properties reflect the differentiation potential of adipose-derived mesenchymal stem cellsProceedings of the National Academy of Sciences of the United States of America2012182
27Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sitesNature Structural and Molecular Biology2010181
28IGF-1 Modulates N and L Calcium Channels in a PI 3-Kinase-Dependent MannerNeuron1997169
29Living without oxygen: lessons from the freshwater turtleComparative Biochemistry and Physiology Part A, Molecular & Integrative Physiology2000168
30Three Dimensional Structure of the MqsR:MqsA Complex: A Novel TA Pair Comprised of a Toxin Homologous to RelE and an Antitoxin with Unique PropertiesPLoS Pathogens2009159
31Oral delivery of proteins by biodegradable nanoparticlesAdvanced Drug Delivery Reviews2013156
32Rods, tori, and honeycombs: the directed self‐assembly of microtissues with prescribed microscale geometriesFASEB Journal2007148
33Hibernating without Oxygen: Physiological Adaptations of the Painted TurtleJournal of Physiology2002138
34Role of the cervical lymphatics in the Th2-type hierarchy of CNS immune regulation1This work was supported by National Institute of Health Grant (RO1 NS33070-03) and The Brain Tumor Society.1Journal of Neuroimmunology1999135
35Nuclear Membrane-Targeted Gold Nanoparticles Inhibit Cancer Cell Migration and InvasionACS Nano2017135
36Mammalian Target of Rapamycin Contributes to the Acquired Apoptotic Resistance of Human Mesothelioma Multicellular SpheroidsJournal of Biological Chemistry2008130
37Molecular Details of Protein Condensates Probed by Microsecond Long Atomistic SimulationsJournal of Physical Chemistry B2020127
38Akt-Dependent Potentiation of L Channels by Insulin-Like Growth Factor-1 Is Required for Neuronal SurvivalJournal of Neuroscience1999125
39Membrane bending by protein phase separationProceedings of the National Academy of Sciences of the United States of America2021125
40The Molecular Mechanism of Substrate Engagement and Immunosuppressant Inhibition of CalcineurinPLoS Biology2013123
41Role of Sigma-1 Receptor C-terminal Segment in Inositol 1,4,5-Trisphosphate Receptor ActivationJournal of Biological Chemistry2008118
42Expanding the PP2A Interactome by Defining a B56-Specific SLiMStructure2016117
43Multiple Trafficking Signals Regulate Kainate Receptor KA2 Subunit Surface ExpressionJournal of Neuroscience2003113
44Gα i1 and Gα i3 Are Required for Epidermal Growth Factor–Mediated Activation of the Akt-mTORC1 PathwayScience Signaling2009113
45Stress and VTA synapses: implications for addiction and depressionEuropean Journal of Neuroscience2014111
46Drugs of abuse and stress impair LTP at inhibitory synapses in the ventral tegmental areaEuropean Journal of Neuroscience2010110
47Biomechanics of Plaque Rupture: Progress, Problems, and New FrontiersAnnals of Biomedical Engineering2002107
48Structural and Functional Analysis of the GADD34:PP1 eIF2α PhosphataseCell Reports2015107
49Kappa Opioid Receptors Regulate Stress-Induced Cocaine Seeking and Synaptic PlasticityNeuron2013105
50Kainate Receptor Activation Induces Mixed Lineage Kinase-mediated Cellular Signaling Cascades via Post-synaptic Density Protein 95Journal of Biological Chemistry2001104