# | Title | Journal | Year | Citations |
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1 | Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1 | Cancer Cell | 2010 | 6,138 |
2 | Tumour exosome integrins determine organotropic metastasis | Nature | 2015 | 3,688 |
3 | Cellular senescence: when bad things happen to good cells | Nature Reviews Molecular Cell Biology | 2007 | 3,502 |
4 | The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression | Annual Review of Pathology: Mechanisms of Disease | 2010 | 3,486 |
5 | Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET | Nature Medicine | 2012 | 3,098 |
6 | Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor | PLoS Biology | 2008 | 3,067 |
7 | A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes | Cancer Cell | 2006 | 2,729 |
8 | The OBO Foundry: coordinated evolution of ontologies to support biomedical data integration | Nature Biotechnology | 2007 | 1,955 |
9 | ATM Phosphorylates Histone H2AX in Response to DNA Double-strand Breaks | Journal of Biological Chemistry | 2001 | 1,598 |
10 | Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy | Nature Medicine | 2011 | 1,460 |
11 | Senescent fibroblasts promote epithelial cell growth and tumorigenesis: A link between cancer and aging | Proceedings of the National Academy of Sciences of the United States of America | 2001 | 1,412 |
12 | Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression | Nature Medicine | 2011 | 1,296 |
13 | Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1 | Nature Genetics | 1997 | 1,184 |
14 | Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability | Nature | 2005 | 1,159 |
15 | Three-dimensional culture models of normal and malignant breast epithelial cells | Nature Methods | 2007 | 1,131 |
16 | Telomere Shortening Triggers Senescence of Human Cells through a Pathway Involving ATM, p53, and p21CIP1, but Not p16INK4a | Molecular Cell | 2004 | 1,128 |
17 | Genomic and transcriptional aberrations linked to breast cancer pathophysiologies | Cancer Cell | 2006 | 1,125 |
18 | Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts | Nature Cell Biology | 2003 | 1,003 |
19 | The Stromal Proteinase MMP3/Stromelysin-1 Promotes Mammary Carcinogenesis | Cell | 1999 | 994 |
20 | Of Extracellular Matrix, Scaffolds, and Signaling: Tissue Architecture Regulates Development, Homeostasis, and Cancer | Annual Review of Cell and Developmental Biology | 2006 | 976 |
21 | Regulation of matrix biology by matrix metalloproteinases | Current Opinion in Cell Biology | 2004 | 961 |
22 | The perivascular niche regulates breast tumour dormancy | Nature Cell Biology | 2013 | 945 |
23 | β4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium | Cancer Cell | 2002 | 880 |
24 | Tau PET patterns mirror clinical and neuroanatomical variability in Alzheimer’s disease | Brain | 2016 | 833 |
25 | A Versatile Viral System for Expression and Depletion of Proteins in Mammalian Cells | PLoS ONE | 2009 | 805 |
26 | Reciprocal interactions between β1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures: A different perspective in epithelial biology | Proceedings of the National Academy of Sciences of the United States of America | 1998 | 762 |
27 | p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype | EMBO Journal | 2011 | 755 |
28 | Dishevelled controls cell polarity during Xenopus gastrulation | Nature | 2000 | 705 |
29 | Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers | Cell | 2020 | 691 |
30 | Accurate assessment of mass, models and resolution by small-angle scattering | Nature | 2013 | 670 |
31 | The 7SK small nuclear RNA inhibits the CDK9/cyclin T1 kinase to control transcription | Nature | 2001 | 629 |
32 | Cellular senescence as a tumor-suppressor mechanism | Trends in Cell Biology | 2001 | 629 |
33 | MiMIC: a highly versatile transposon insertion resource for engineering Drosophila melanogaster genes | Nature Methods | 2011 | 620 |
34 | Single cell analysis: the new frontier in ‘omics’ | Trends in Biotechnology | 2010 | 613 |
35 | XPD Helicase Structures and Activities: Insights into the Cancer and Aging Phenotypes from XPD Mutations | Cell | 2008 | 593 |
36 | High-Resolution Microtubule Structures Reveal the Structural Transitions in αβ-Tubulin upon GTP Hydrolysis | Cell | 2014 | 582 |
37 | Physical fitness and activity as separate heart disease risk factors: a meta-analysis | Medicine and Science in Sports and Exercise | 2001 | 572 |
38 | Tissue Geometry Determines Sites of Mammary Branching Morphogenesis in Organotypic Cultures | Science | 2006 | 545 |
39 | The organizing principle: microenvironmental influences in the normal and malignant breast | Differentiation | 2002 | 542 |
40 | The Carnegie Protein Trap Library: A Versatile Tool for Drosophila Developmental Studies | Genetics | 2007 | 529 |
41 | Stromal-epithelial interactions in aging and cancer: senescent fibroblasts alter epithelial cell differentiation | Journal of Cell Science | 2005 | 517 |
42 | Genetic evidence for three unique components in primary cell-wall cellulose synthase complexes in Arabidopsis | Proceedings of the National Academy of Sciences of the United States of America | 2007 | 506 |
43 | Molecular Characterization of the Cytotoxic Mechanism of Multiwall Carbon Nanotubes and Nano-Onions on Human Skin Fibroblast | Nano Letters | 2005 | 499 |
44 | Chromosome Instability and Defective Recombinational Repair in Knockout Mutants of the Five Rad51 Paralogs | Molecular and Cellular Biology | 2001 | 495 |
45 | Structural visualization of key steps in human transcription initiation | Nature | 2013 | 490 |
46 | XRCC2 and XRCC3, New Human Rad51-Family Members, Promote Chromosome Stability and Protect against DNA Cross-Links and Other Damages | Molecular Cell | 1998 | 488 |
47 | Negative Feedback Regulation of TGF-β Signaling by the SnoN Oncoprotein | Science | 1999 | 480 |
48 | Cancer and ageing: rival demons? | Nature Reviews Cancer | 2003 | 465 |
49 | Structural Mechanism of Abscisic Acid Binding and Signaling by Dimeric PYR1 | Science | 2009 | 457 |
50 | Characterizing flexible and intrinsically unstructured biological macromolecules by SAS using the Porod‐Debye law | Biopolymers | 2011 | 440 |