# | Title | Journal | Year | Citations |
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1 | Site-directed mutagenesis by overlap extension using the polymerase chain reaction | Gene | 1989 | 7,939 |
2 | Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion | Nature Medicine | 2002 | 4,217 |
3 | Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension | Gene | 1989 | 2,982 |
4 | Heterogeneity of multiple sclerosis lesions: Implications for the pathogenesis of demyelination | Annals of Neurology | 2000 | 2,892 |
5 | B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion | Nature Medicine | 1999 | 2,200 |
6 | Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response | Nature | 2018 | 1,836 |
7 | Blockade of B7-H1 improves myeloid dendritic cell–mediated antitumor immunity | Nature Medicine | 2003 | 1,157 |
8 | Diagnosis and management of adult coeliac disease: guidelines from the British Society of Gastroenterology | Gut | 2014 | 870 |
9 | B7-H3: A costimulatory molecule for T cell activation and IFN-γ production | Nature Immunology | 2001 | 856 |
10 | Blockade of B7-H1 and PD-1 by Monoclonal Antibodies Potentiates Cancer Therapeutic Immunity | Cancer Research | 2005 | 819 |
11 | Isolation of a Protein Target of the FKBP12-Rapamycin Complex in Mammalian Cells | Journal of Biological Chemistry | 1995 | 764 |
12 | Blockade of B7-H1 and PD-1 by monoclonal antibodies potentiates cancer therapeutic immunity | Cancer Research | 2005 | 687 |
13 | The eosinophil and bronchial asthma: Current understanding | Journal of Allergy and Clinical Immunology | 1990 | 659 |
14 | B7-H4, a Molecule of the B7 Family, Negatively Regulates T Cell Immunity | Immunity | 2003 | 623 |
15 | Receptor-Mediated Monitoring of Tissue Well-Being Via Detection of Soluble Heparan Sulfate by Toll-Like Receptor 4 | Journal of Immunology | 2002 | 605 |
16 | Calcium-Channel Antibodies in the Lambert–Eaton Syndrome and Other Paraneoplastic Syndromes | New England Journal of Medicine | 1995 | 600 |
17 | A direct linkage between the phosphoinositide 3-kinase-AKT signaling pathway and the mammalian target of rapamycin in mitogen-stimulated and transformed cells | Cancer Research | 2000 | 570 |
18 | CRMP-5 neuronal autoantibody: Marker of lung cancer and thymoma-related autoimmunity | Annals of Neurology | 2001 | 528 |
19 | Paraneoplastic and oncologic profiles of patients seropositive for type 1 antineuronal nuclear autoantibodies | Neurology | 1998 | 490 |
20 | EPSTEIN-BARR VIRUS-INDUCED POSTTRANSPLANT LYMPHOPROLIFERATIVE DISORDERS | Transplantation | 1999 | 489 |
21 | Expression of BCMA, TACI, and BAFF-R in multiple myeloma: a mechanism for growth and survival | Blood | 2004 | 474 |
22 | Airway Memory CD4 + T Cells Mediate Protective Immunity against Emerging Respiratory Coronaviruses | Immunity | 2016 | 468 |
23 | A FAM21-Containing WASH Complex Regulates Retromer-Dependent Sorting | Developmental Cell | 2009 | 447 |
24 | A novel IL-1 family cytokine, IL-33, potently activates human eosinophils | Journal of Allergy and Clinical Immunology | 2008 | 436 |
25 | Toxicity of Eosinophil Cationic Proteins for Guinea Pig Tracheal EpitheliumIn Vitro | The American Review of Respiratory Disease | 1989 | 425 |
26 | Tumor-Infiltrating Dendritic Cells in Cancer Pathogenesis | Journal of Immunology | 2015 | 369 |
27 | LIGHT, a TNF-Like Molecule, Costimulates T Cell Proliferation and Is Required for Dendritic Cell-Mediated Allogeneic T Cell Response | Journal of Immunology | 2000 | 355 |
28 | Activation of IκB Kinase β by Protein Kinase C Isoforms | Molecular and Cellular Biology | 1999 | 354 |
29 | NKG2D-DAP10 triggers human NK cell–mediated killing via a Syk-independent regulatory pathway | Nature Immunology | 2003 | 335 |
30 | Pembrolizumab in patients with CLL and Richter transformation or with relapsed CLL | Blood | 2017 | 335 |
31 | Structural and Functional Analysis of the Costimulatory Receptor Programmed Death-1 | Immunity | 2004 | 331 |
32 | Major Histocompatibility Complex Class I–Recognizing Receptors Are Disease Risk Genes in Rheumatoid Arthritis | Journal of Experimental Medicine | 2001 | 316 |
33 | VAV proteins as signal integrators for multi-subunit immune-recognition receptors | Nature Reviews Immunology | 2002 | 312 |
34 | Upregulation of Fas ligand expression by human immunodeficiency virus in human macrophages mediates apoptosis of uninfected T lymphocytes | Journal of Virology | 1996 | 307 |
35 | The eosinophil as a mediator of damage to respiratory epithelium: A model for bronchial hyperreactivity | Journal of Allergy and Clinical Immunology | 1988 | 300 |
36 | The Microbiome of Aseptically Collected Human Breast Tissue in Benign and Malignant Disease | Scientific Reports | 2016 | 299 |
37 | Modulation of T-cell-mediated immunity in tumor and graft-versus-host disease models through the LIGHT co-stimulatory pathway | Nature Medicine | 2000 | 293 |
38 | Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade | Science Translational Medicine | 2018 | 288 |
39 | Biological implications of cell fusion | Nature Reviews Molecular Cell Biology | 2005 | 284 |
40 | Molecular outcomes of neuromyelitis optica (NMO)-IgG binding to aquaporin-4 in astrocytes | Proceedings of the National Academy of Sciences of the United States of America | 2012 | 281 |
41 | H-2 haplotypes, genes and antigens: Second listing | Immunogenetics | 1983 | 261 |
42 | Molecular Modeling and Functional Mapping of B7-H1 and B7-DC Uncouple Costimulatory Function from PD-1 Interaction | Journal of Experimental Medicine | 2003 | 259 |
43 | B7-H1 pathway and its role in the evasion of tumor immunity | Journal of Molecular Medicine | 2003 | 249 |
44 | Interferon-β enhances monocyte and dendritic cell expression of B7-H1 (PD-L1), a strong inhibitor of autologous T-cell activation: relevance for the immune modulatory effect in multiple sclerosis | Journal of Neuroimmunology | 2004 | 249 |
45 | Genetic Evidence for Differential Coupling of Syk Family Kinases to the T-Cell Receptor: Reconstitution Studies in a ZAP-70-Deficient Jurkat T-Cell Line | Molecular and Cellular Biology | 1998 | 248 |
46 | Retriever is a multiprotein complex for retromer-independent endosomal cargo recycling | Nature Cell Biology | 2017 | 243 |
47 | AXL induces epithelial-to-mesenchymal transition and regulates the function of breast cancer stem cells | Oncogene | 2014 | 235 |
48 | Genomic Organization and Expression Analysis of B7-H4, an Immune Inhibitory Molecule of the B7 Family | Journal of Immunology | 2003 | 233 |
49 | Neuronal nicotinic ACh receptor antibody in subacute autonomic neuropathy and cancer‐related syndromes | Neurology | 1998 | 229 |
50 | Increased expression of BubR1 protects against aneuploidy and cancer and extends healthy lifespan | Nature Cell Biology | 2013 | 229 |