| # | Title | Journal | Year | Citations |
|---|
| 1 | Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines | Journal of Extracellular Vesicles | 2018 | 6,961 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 3 | Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis | American Journal of Physiology - Lung Cellular and Molecular Physiology | 2015 | 570 |
| 4 | Congenital myasthenic syndromes: pathogenesis, diagnosis, and treatment | Lancet Neurology, The | 2015 | 413 |
| 5 | Targeting senescent cells alleviates obesity‐induced metabolic dysfunction | Aging Cell | 2019 | 395 |
| 6 | Charting cellular identity during human in vitro β-cell differentiation | Nature | 2019 | 358 |
| 7 | Sex Differences and Sex Steroids in Lung Health and Disease | Endocrine Reviews | 2012 | 320 |
| 8 | Senescent cells evade immune clearance via HLA-E-mediated NK and CD8+ T cell inhibition | Nature Communications | 2019 | 281 |
| 9 | Gut Microbiota-Produced Tryptamine Activates an Epithelial G-Protein-Coupled Receptor to Increase Colonic Secretion | Cell Host and Microbe | 2018 | 268 |
| 10 | Multiple-channel scaffolds to promote spinal cord axon regeneration | Biomaterials | 2006 | 262 |
| 11 | Tangential Flow Filtration for Highly Efficient Concentration of Extracellular Vesicles from Large Volumes of Fluid | Cells | 2018 | 262 |
| 12 | Sex and ageing differences in resting arterial pressure regulation: the role of the β‐adrenergic receptors | Journal of Physiology | 2011 | 258 |
| 13 | Cellular senescence and senolytics: the path to the clinic | Nature Medicine | 2022 | 257 |
| 14 | Ultrasound Elastography: The New Frontier in Direct Measurement of Muscle Stiffness | Archives of Physical Medicine and Rehabilitation | 2014 | 246 |
| 15 | Role of potassium in regulating blood flow and blood pressure | American Journal of Physiology - Regulatory Integrative and Comparative Physiology | 2006 | 232 |
| 16 | Longitudinal Multi-omics Reveals Subset-Specific Mechanisms Underlying Irritable Bowel Syndrome | Cell | 2020 | 217 |
| 17 | Adaptive nonlocal means filtering based on local noise level for CT denoising | Medical Physics | 2013 | 201 |
| 18 | Review of MR elastography applications and recent developments | Journal of Magnetic Resonance Imaging | 2012 | 200 |
| 19 | Exercise, cognitive function, and aging | American Journal of Physiology - Advances in Physiology Education | 2015 | 198 |
| 20 | Telomere dysfunction in ageing and age-related diseases | Nature Cell Biology | 2022 | 194 |
| 21 | Mitochondria-to-nucleus retrograde signaling drives formation of cytoplasmic chromatin and inflammation in senescence | Genes and Development | 2020 | 188 |
| 22 | Whole‐body senescent cell clearance alleviates age‐related brain inflammation and cognitive impairment in mice | Aging Cell | 2021 | 186 |
| 23 | Current Status of Developments and Applications of Micro-CT | Annual Review of Biomedical Engineering | 2011 | 185 |
| 24 | Evaluation of conventional imaging performance in a research whole-body CT system with a photon-counting detector array | Physics in Medicine and Biology | 2016 | 185 |
| 25 | Senolytics reduce coronavirus-related mortality in old mice | Science | 2021 | 184 |
| 26 | Measuring the effects of aging and sex on regional brain stiffness with MR elastography in healthy older adults | NeuroImage | 2015 | 183 |
| 27 | Methodology for isolation, identification and characterization of microvesicles in peripheral blood | Journal of Immunological Methods | 2012 | 182 |
| 28 | Functionalized Carbon Nanotube and Graphene Oxide Embedded Electrically Conductive Hydrogel Synergistically Stimulates Nerve Cell Differentiation | ACS Applied Materials & Interfaces | 2017 | 179 |
| 29 | Mitochondrial Dysfunction in Airway Disease | Chest | 2017 | 168 |
| 30 | Pharmacological clearance of senescent cells improves survival and recovery in aged mice following acute myocardial infarction | Aging Cell | 2019 | 156 |
| 31 | Post-inflammatory colonic afferent sensitisation: different subtypes, different pathways and different time courses | Gut | 2009 | 154 |
| 32 | Cigarette smoke-induced mitochondrial fragmentation and dysfunction in human airway smooth muscle | American Journal of Physiology - Lung Cellular and Molecular Physiology | 2014 | 150 |
| 33 | Unbiased Risk Estimates for Singular Value Thresholding and Spectral Estimators | IEEE Transactions on Signal Processing | 2013 | 148 |
| 34 | Human airway organoid engineering as a step toward lung regeneration and disease modeling | Biomaterials | 2017 | 146 |
| 35 | A Chronically Implantable Neural Coprocessor for Investigating the Treatment of Neurological Disorders | IEEE Transactions on Biomedical Circuits and Systems | 2018 | 138 |
| 36 | P300 Acetyltransferase Mediates Stiffness-Induced Activation of Hepatic Stellate Cells Into Tumor-Promoting Myofibroblasts | Gastroenterology | 2018 | 136 |
| 37 | Senescent human melanocytes drive skin ageing via paracrine telomere dysfunction | EMBO Journal | 2019 | 136 |
| 38 | Neurostimulation Devices for the Treatment of Neurologic Disorders | Mayo Clinic Proceedings | 2017 | 136 |
| 39 | Selective YAP/TAZ inhibition in fibroblasts via dopamine receptor D1 agonism reverses fibrosis | Science Translational Medicine | 2019 | 134 |
| 40 | Mechanical Stretch Increases Expression of CXCL1 in Liver Sinusoidal Endothelial Cells to Recruit Neutrophils, Generate Sinusoidal Microthombi, and Promote Portal Hypertension | Gastroenterology | 2019 | 134 |
| 41 | Low‐dose CT for the detection and classification of metastatic liver lesions: Results of the 2016 Low Dose CT Grand Challenge | Medical Physics | 2017 | 132 |
| 42 | Clostridioides difficile uses amino acids associated with gut microbial dysbiosis in a subset of patients with diarrhea | Science Translational Medicine | 2018 | 128 |
| 43 | Production of the gaseous signal molecule hydrogen sulfide in mouse tissues | Journal of Neurochemistry | 2008 | 127 |
| 44 | Sex steroid signaling: Implications for lung diseases | Journal of Neurochemistry | 2015 | 125 |
| 45 | Macrophages contribute to the pathogenesis of sclerosing cholangitis in mice | Journal of Hepatology | 2018 | 119 |
| 46 | Interstitial cells of Cajal in diabetic gastroenteropathy | Neurogastroenterology and Motility | 2008 | 118 |
| 47 | Hypercapnic Acidosis Impairs Plasma Membrane Wound Resealing in Ventilator-injured Lungs | American Journal of Respiratory and Critical Care Medicine | 2005 | 117 |
| 48 | Deep brain stimulation for treatment-resistant depression: Efficacy, safety and mechanisms of action | Neuroscience and Biobehavioral Reviews | 2012 | 117 |
| 49 | Kitlow Stem Cells Cause Resistance to Kit/Platelet-Derived Growth Factor α Inhibitors in Murine Gastrointestinal Stromal Tumors | Gastroenterology | 2010 | 112 |
| 50 | Integrin β1-enriched extracellular vesicles mediate monocyte adhesion and promote liver inflammation in murine NASH | Journal of Hepatology | 2019 | 112 |
