| # | Title | Journal | Year | Citations |
|---|
| 1 | ESPEN guidelines on nutrition in cancer patients | Clinical Nutrition | 2017 | 1,855 |
| 2 | Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS) | Clinical Neurophysiology | 2014 | 1,647 |
| 3 | EULAR recommendations for the use of imaging in large vessel vasculitis in clinical practice | Annals of the Rheumatic Diseases | 2018 | 753 |
| 4 | New insights into the genetic etiology of Alzheimer’s disease and related dementias | Nature Genetics | 2022 | 700 |
| 5 | Adenosine as a neuromodulator and as a homeostatic regulator in the nervous system: different roles, different sources and different receptors | Neurochemistry International | 2001 | 554 |
| 6 | Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis | Nature Genetics | 2016 | 494 |
| 7 | ESPEN practical guideline: Clinical Nutrition in cancer | Clinical Nutrition | 2021 | 472 |
| 8 | Dietary Counseling Improves Patient Outcomes: A Prospective, Randomized, Controlled Trial in Colorectal Cancer Patients Undergoing Radiotherapy | Journal of Clinical Oncology | 2005 | 464 |
| 9 | Adenosine receptors in the nervous system: pathophysiological implications | Progress in Neurobiology | 2002 | 452 |
| 10 | To be or not to be in the nucleolus | Nature Cell Biology | 2000 | 346 |
| 11 | Mental health outcomes in times of economic recession: a systematic literature review | BMC Public Health | 2015 | 345 |
| 12 | Prognosis for patients with amyotrophic lateral sclerosis: development and validation of a personalised prediction model | Lancet Neurology, The | 2018 | 342 |
| 13 | miR-34a/SIRT1/p53 is suppressed by ursodeoxycholic acid in the rat liver and activated by disease severity in human non-alcoholic fatty liver disease | Journal of Hepatology | 2013 | 300 |
| 14 | The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates | Rna | 2000 | 298 |
| 15 | Summary of the recommendations of the EFNS/MDS‐ES review on therapeutic management of Parkinson's disease | European Journal of Neurology | 2013 | 290 |
| 16 | Quantitative wearable sensors for objective assessment of Parkinson's disease | Movement Disorders | 2013 | 287 |
| 17 | Prevalence and prognosis of Alzheimer’s disease at the mild cognitive impairment stage | Brain | 2015 | 284 |
| 18 | A prospective survey in European Society of Cardiology member countries of atrial fibrillation management: baseline results of EURObservational Research Programme Atrial Fibrillation (EORP-AF) Pilot General Registry | Europace | 2014 | 280 |
| 19 | Cancer: disease and nutrition are key determinants of patients? quality of life | Supportive Care in Cancer | 2004 | 274 |
| 20 | A Pan‐European Study of theC9orf72Repeat Associated withFTLD: Geographic Prevalence, Genomic Instability, and Intermediate Repeats | Human Mutation | 2013 | 247 |
| 21 | Dbp5, a DEAD-box protein required for mRNA export, is recruited to the cytoplasmic fibrils of nuclear pore complex via a conserved interaction with CAN/Nup159p | EMBO Journal | 1999 | 244 |
| 22 | Dynamic association of RNA-editing enzymes with the nucleolus | Journal of Cell Science | 2003 | 231 |
| 23 | Nuclear inclusions in oculopharyngeal muscular dystrophy consist of poly(A) binding protein 2 aggregates which sequester poly(A) RNA | Human Molecular Genetics | 2000 | 226 |
| 24 | Vesicular Stomatitis Virus Matrix Protein Inhibits Host Cell Gene Expression by Targeting the Nucleoporin Nup98 | Molecular Cell | 2000 | 226 |
| 25 | DYSBOT: A single-blind, randomized parallel study to determine whether any differences can be detected in the efficacy and tolerability of two formulations of botulinum toxin type A—Dysport and Botox—assuming a ratio of 4:1 | Movement Disorders | 1997 | 220 |
| 26 | Global interim guidance on coronavirus disease 2019 (COVID‐19) during pregnancy and puerperium from FIGO and allied partners: Information for healthcare professionals | International Journal of Gynecology and Obstetrics | 2020 | 220 |
| 27 | Opicapone as an adjunct to levodopa in patients with Parkinson's disease and end-of-dose motor fluctuations: a randomised, double-blind, controlled trial | Lancet Neurology, The | 2016 | 219 |
| 28 | Awaji Criteria for the Diagnosis of Amyotrophic Lateral Sclerosis | Archives of Neurology | 2012 | 211 |
| 29 | TAP (NXF1) Belongs to a Multigene Family of Putative RNA Export Factors with a Conserved Modular Architecture | Molecular and Cellular Biology | 2000 | 210 |
| 30 | Risk of pneumonia associated with use of angiotensin converting enzyme inhibitors and angiotensin receptor blockers: systematic review and meta-analysis | BMJ, The | 2012 | 206 |
| 31 | The Spinal Muscular Atrophy Disease Gene Product, Smn | Journal of Cell Biology | 1999 | 205 |
| 32 | Depression and coronary heart disease: 2018 position paper of the ESC working group on coronary pathophysiology and microcirculation | European Heart Journal | 2020 | 203 |
| 33 | Adenosine A2A receptor facilitation of hippocampal synaptic transmission is dependent on tonic A1 receptor inhibition | Neuroscience | 2002 | 201 |
| 34 | Developments in medical education in response to the COVID-19 pandemic: A rapid BEME systematic review: BEME Guide No. 63 | Medical Teacher | 2020 | 201 |
| 35 | Effectiveness of needle and syringe Programmes in people who inject drugs – An overview of systematic reviews | BMC Public Health | 2017 | 200 |
| 36 | Caffeine Exposure and the Risk of Parkinson's Disease: A Systematic Review and Meta-Analysis of Observational Studiess | Journal of Alzheimer's Disease | 2010 | 196 |
| 37 | Inefficient processing impairs release of RNA from the site of transcription | EMBO Journal | 1999 | 194 |
| 38 | Exosomes secreted by cardiomyocytes subjected to ischaemia promote cardiac angiogenesis | Cardiovascular Research | 2017 | 193 |
| 39 | Boronic acids as building blocks for the construction of therapeutically useful bioconjugates | Chemical Society Reviews | 2019 | 191 |
| 40 | Nutritional Deterioration in Cancer: The Role of Disease and Diet | Clinical Oncology | 2003 | 187 |
| 41 | The coiled body | Trends in Cell Biology | 1993 | 185 |
| 42 | Intracellular Macromolecular Mobility Measured by Fluorescence Recovery after Photobleaching with Confocal Laser Scanning Microscopes | Molecular Biology of the Cell | 2004 | 184 |
| 43 | Performance and complications of lumbar puncture in memory clinics: Results of the multicenter lumbar puncture feasibility study | Alzheimer's and Dementia | 2016 | 179 |
| 44 | Cross Talk Between A1 and A2A Adenosine Receptors in the Hippocampus and Cortex of Young Adult and Old Rats | Journal of Neurophysiology | 1999 | 177 |
| 45 | Is the OSCE a feasible tool to assess competencies in undergraduate medical education? | Medical Teacher | 2013 | 177 |
| 46 | Non-alcoholic steatohepatitis: From cell biology to clinical practice | Journal of Hepatology | 2006 | 176 |
| 47 | Consensus statement on the definition of neurogenic supine hypertension in cardiovascular autonomic failure by the American Autonomic Society (AAS) and the European Federation of Autonomic Societies (EFAS) | Clinical Autonomic Research | 2018 | 176 |
| 48 | Necroptosis is a key pathogenic event in human and experimental murine models of non-alcoholic steatohepatitis | Clinical Science | 2015 | 175 |
| 49 | Age at symptom onset and death and disease duration in genetic frontotemporal dementia: an international retrospective cohort study | Lancet Neurology, The | 2020 | 175 |
| 50 | ATP as a presynaptic modulator | Life Sciences | 2000 | 174 |
