| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 2 | Comparison of Metabolic Pathways between Cancer Cells and Stromal Cells in Colorectal Carcinomas: a Metabolic Survival Role for Tumor-Associated Stroma | Cancer Research | 2006 | 406 |
| 3 | Lactate dehydrogenase-5 (LDH-5) overexpression in non-small-cell lung cancer tissues is linked to tumour hypoxia, angiogenic factor production and poor prognosis | British Journal of Cancer | 2003 | 328 |
| 4 | Hypoxia-inducible factor (HIF1A and HIF2A), angiogenesis, and chemoradiotherapy outcome of squamous cell head-and-neck cancer | International Journal of Radiation Oncology Biology Physics | 2002 | 311 |
| 5 | Endogenous Markers of Two Separate Hypoxia Response Pathways (hypoxia inducible factor 2 alpha and carbonic anhydrase 9) Are Associated With Radiotherapy Failure in Head and Neck Cancer Patients Recruited in the CHART Randomized Trial | Journal of Clinical Oncology | 2006 | 276 |
| 6 | Expression of hypoxia-inducible carbonic anhydrase-9 relates to angiogenic pathways and independently to poor outcome in non-small cell lung cancer | Cancer Research | 2001 | 249 |
| 7 | VEGF gene sequence variation defines VEGF gene expression status and angiogenic activity in non-small cell lung cancer | Lung Cancer | 2004 | 246 |
| 8 | Hypoxia-regulated carbonic anhydrase-9 (CA9) relates to poor vascularization and resistance of squamous cell head and neck cancer to chemoradiotherapy | Clinical Cancer Research | 2001 | 147 |
| 9 | Beclin 1 over- and underexpression in colorectal cancer: distinct patterns relate to prognosis and tumour hypoxia | British Journal of Cancer | 2010 | 141 |
| 10 | Cancer stem cell phenotype relates to radio-chemotherapy outcome in locally advanced squamous cell head–neck cancer | British Journal of Cancer | 2012 | 122 |
| 11 | The CD44+/CD24− phenotype relates to ‘triple-negative’ state and unfavorable prognosis in breast cancer patients | Medical Oncology | 2011 | 120 |
| 12 | Lactate Dehydrogenase Isoenzymes 1 and 5: Differential Expression by Neoplastic and Stromal Cells in Non-Small Cell Lung Cancer and Other Epithelial Malignant Tumors | Tumor Biology | 2003 | 100 |
| 13 | The presence of tumor-infiltrating FOXP3+ lymphocytes correlates with intratumoral angiogenesis in endometrial cancer | Gynecologic Oncology | 2008 | 98 |
| 14 | Prognostic relevance of light chain 3 (LC3A) autophagy patterns in colorectal adenocarcinomas | Journal of Clinical Pathology | 2010 | 83 |
| 15 | The Notch Pathway in Breast Cancer Progression | Scientific World Journal, The | 2018 | 83 |
| 16 | Increased expression of transcription factor EB (TFEB) is associated with autophagy, migratory phenotype and poor prognosis in non-small cell lung cancer | Lung Cancer | 2015 | 79 |
| 17 | The angiogenic ?vascular endothelial growth factor/flk-1(KDR) receptor? pathway in patients with endometrial carcinoma | Cancer | 2001 | 73 |
| 18 | Lactate dehydrogenase 5 isoenzyme overexpression defines resistance of prostate cancer to radiotherapy | British Journal of Cancer | 2014 | 69 |
| 19 | High Beclin 1 expression defines a poor prognosis in endometrial adenocarcinomas | Gynecologic Oncology | 2011 | 64 |
| 20 | Therapeutic interactions of autophagy with radiation and temozolomide in glioblastoma: evidence and issues to resolve | British Journal of Cancer | 2016 | 61 |
| 21 | The vascular network of tumours ? what is it not for? | Journal of Pathology | 2003 | 59 |
| 22 | The metabolic interactions between tumor cells and tumor-associated stroma (TAS) in prostatic cancer | Cancer Biology and Therapy | 2012 | 55 |
| 23 | Hypoxia-inducible proteins HIF1α and lactate dehydrogenase LDH5, key markers of anaerobic metabolism, relate with stem cell markers and poor post-radiotherapy outcome in bladder cancer | International Journal of Radiation Biology | 2016 | 55 |
| 24 | Endogenous markers of hypoxia/anaerobic metabolism and anemia in primary colorectal cancer | Cancer Science | 2006 | 53 |
| 25 | Autophagy proteins in prostate cancer: Relation with anaerobic metabolism and Gleason score11The study was financially supported by the Tumor and Angiogenesis Research Group. | Urologic Oncology: Seminars and Original Investigations | 2014 | 52 |
| 26 | Loss of expression and nuclear/cytoplasmic localization of the FOXP1 forkhead transcription factor are common events in early endometrial cancer: relationship with estrogen receptors and HIF-1α expression | Modern Pathology | 2006 | 51 |
| 27 | Hypoxia inducible factor (HIF1α and HIF2α) and carbonic anhydrase 9 (CA9) expression and response of head-neck cancer to hypofractionated and accelerated radiotherapy | International Journal of Radiation Biology | 2008 | 42 |
| 28 | Postmastectomy Hypofractionated and Accelerated Radiation Therapy With (and Without) Subcutaneous Amifostine Cytoprotection | International Journal of Radiation Oncology Biology Physics | 2013 | 42 |
| 29 | Fever-Range Hyperthermia vs. Hypothermia Effect on Cancer Cell Viability, Proliferation and HSP90 Expression | PLoS ONE | 2015 | 42 |
| 30 | Hypoxia-activated tumor pathways of angiogenesis and pH regulation independent of anemia in head-and-neck cancer | International Journal of Radiation Oncology Biology Physics | 2004 | 39 |
| 31 | Patterns of episialin/MUC1 expression in endometrial carcinomas and prognostic relevance | Histopathology | 2002 | 37 |
| 32 | Metabolic cooperation between co-cultured lung cancer cells and lung fibroblasts | Laboratory Investigation | 2017 | 37 |
| 33 | Programmed death-1 receptor (PD-1) and PD-ligand-1 (PD-L1) expression in non-small cell lung cancer and the immune-suppressive effect of anaerobic glycolysis | Medical Oncology | 2019 | 36 |
| 34 | C2028T polymorphism in exon 12 and dinucleotide repeat polymorphism in intron 13 of the HIF-1α gene define HIF-1α protein expression in non-small cell lung cancer | Lung Cancer | 2006 | 35 |
| 35 | Effect of Amifostine on Response Rates in Locally Advanced Non–Small-Cell Lung Cancer Patients Treated on Randomized Controlled Trials: A Meta-Analysis | International Journal of Radiation Oncology Biology Physics | 2007 | 35 |
| 36 | Thymidine phosphorylase expression in normal, hyperplastic and neoplastic prostates: correlation with tumour associated macrophages, infiltrating lymphocytes, and angiogenesis | British Journal of Cancer | 2002 | 34 |
| 37 | Ectonucleotidase CD73 and CD39 expression in non-small cell lung cancer relates to hypoxia and immunosuppressive pathways | Life Sciences | 2020 | 34 |
| 38 | Delta-like ligand 4 (DLL4) in the plasma and neoplastic tissues from breast cancer patients: correlation with metastasis | Medical Oncology | 2014 | 31 |
| 39 | Radiochemotherapy With Cetuximab, Cisplatin, and Amifostine for Locally Advanced Head and Neck Cancer: A Feasibility Study | International Journal of Radiation Oncology Biology Physics | 2010 | 29 |
| 40 | LC3A, LC3B and Beclin-1 Expression in Gastric Cancer | Anticancer Research | 2018 | 29 |
| 41 | Bevacizumab, Capecitabine, Amifostine, and Preoperative Hypofractionated Accelerated Radiotherapy (HypoArc) for Rectal Cancer: A Phase II Study | International Journal of Radiation Oncology Biology Physics | 2011 | 28 |
| 42 | Intensified autophagy compromises the efficacy of radiotherapy against prostate cancer | Biochemical and Biophysical Research Communications | 2015 | 28 |
| 43 | Repression of the autophagic response sensitises lung cancer cells to radiation and chemotherapy | British Journal of Cancer | 2016 | 28 |
| 44 | Serum VEGF levels and tissue activation of VEGFR2/KDR receptors in patients with breast and gynecologic cancer | Cytokine | 2011 | 27 |
| 45 | Important Role of Autophagy in Endothelial Cell Response to Ionizing Radiation | PLoS ONE | 2014 | 27 |
| 46 | Normal tissue radioprotection by amifostine via Warburg-type effects | Scientific Reports | 2016 | 27 |
| 47 | Serum C-reactive Protein (CRP) Levels in Cancer Patients are Linked with Tumor Burden and are Reduced by Anti-hypertensive Medication | Inflammation | 2009 | 26 |
| 48 | Hypofractionated Accelerated Radiotherapy With Cytoprotection Combined With Trastuzumab, Liposomal Doxorubicine, and Docetaxel in c-erbB-2???Positive Breast Cancer | American Journal of Clinical Oncology: Cancer Clinical Trials | 2005 | 25 |
| 49 | FOXP3 infiltrating lymphocyte density and PD-L1 expression in operable non-small cell lung carcinoma | Experimental Lung Research | 2019 | 24 |
| 50 | Carbonic anhydrase 9 (CA9) expression in non-small-cell lung cancer: correlation with regulatory FOXP3+T-cell tumour stroma infiltration | British Journal of Cancer | 2020 | 24 |
