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Systems Biology Institute
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top-articles
Systems Biology Institute
85
(top 1%)
papers
4.0K
(top 1%)
citations
30
(top 1%)
h
-index
63
(top 1%)
g
-index
109
all documents
4.8K
doc citations
935
citing journals
Top Articles
#
Title
Journal
Year
Citations
1
Genomically Recoded Organisms Expand Biological Functions
Science
2013
721
2
Forcing cells into shape: the mechanics of actomyosin contractility
Nature Reviews Molecular Cell Biology
2015
487
3
Recoded organisms engineered to depend on synthetic amino acids
Nature
2015
288
4
The real cost of sequencing: scaling computation to keep pace with data generation
Genome Biology
2016
264
5
Evolution of translation machinery in recoded bacteria enables multi-site incorporation of nonstandard amino acids
Nature Biotechnology
2015
234
6
Guanylate-binding proteins convert cytosolic bacteria into caspase-4 signaling platforms
Nature Immunology
2020
182
7
Cell-free protein synthesis from genomically recoded bacteria enables multisite incorporation of noncanonical amino acids
Nature Communications
2018
165
8
Hydrogel-based biocontainment of bacteria for continuous sensing and computation
Nature Chemical Biology
2021
110
9
Robust production of recombinant phosphoproteins using cell-free protein synthesis
Nature Communications
2015
106
10
Rapid editing and evolution of bacterial genomes using libraries of synthetic DNA
Nature Protocols
2014
101
11
Protein Aggregation Caused by Aminoglycoside Action Is Prevented by a Hydrogen Peroxide Scavenger
Molecular Cell
2012
98
12
Crystal Structure of an Insect Antifreeze Protein and Its Implications for Ice Binding
Journal of Biological Chemistry
2013
96
13
Precise Editing at DNA Replication Forks Enables Multiplex Genome Engineering in Eukaryotes
Cell
2017
93
14
A flexible codon in genomically recoded Escherichia coli permits programmable protein phosphorylation
Nature Communications
2015
86
15
Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression
Proceedings of the National Academy of Sciences of the United States of America
2014
83
16
The mammalian decidual cell evolved from a cellular stress response
PLoS Biology
2018
79
17
The polycystins are modulated by cellular oxygen-sensing pathways and regulate mitochondrial function
Molecular Biology of the Cell
2017
73
18
Chemical Evolution of a Bacterial Proteome
Angewandte Chemie - International Edition
2015
71
19
Repurposing the translation apparatus for synthetic biology
Current Opinion in Chemical Biology
2015
69
20
Hyperosmotic stress alters the RNA polymerase II interactome and induces readthrough transcription despite widespread transcriptional repression
Molecular Cell
2021
61
21
Next-generation genetic code expansion
Current Opinion in Chemical Biology
2018
57
22
Two interferon-independent double-stranded RNA-induced host defense strategies suppress the common cold virus at warm temperature
Proceedings of the National Academy of Sciences of the United States of America
2016
54
23
Wound healing coordinates actin architectures to regulate mechanical work
Nature Physics
2019
52
24
The statistical geometry of transcriptome divergence in cell-type evolution and cancer
Nature Communications
2015
49
25
Translation system engineering in
Escherichia coli
enhances non‐canonical amino acid incorporation into proteins
Biotechnology and Bioengineering
2017
49
26
Entropy production rate is maximized in non-contractile actomyosin
Nature Communications
2018
48
27
Recombineering and MAGE
Nature Reviews Methods Primers
2021
47
28
Co-stimulation with opposing macrophage polarization cues leads to orthogonal secretion programs in individual cells
Nature Communications
2021
45
29
Precise manipulation of bacterial chromosomes by conjugative assembly genome engineering
Nature Protocols
2014
43
30
Escherichia coli chemotaxis is information limited
Nature Physics
2021
42
31
Genomes by design
Nature Reviews Genetics
2015
41
32
Character identity mechanisms: a conceptual model for comparative-mechanistic biology
Biology and Philosophy
2020
37
33
MS-READ: Quantitative measurement of amino acid incorporation
Biochimica Et Biophysica Acta - General Subjects
2017
35
34
Fundamental Characteristics of Single-Cell Aging in Diploid Yeast
IScience
2018
33
35
Spatial Manipulation with Microfluidics
Frontiers in Bioengineering and Biotechnology
2015
31
36
Encoding human serine phosphopeptides in bacteria for proteome-wide identification of phosphorylation-dependent interactions
Nature Biotechnology
2018
30
37
Cis-Regulatory Evolution of Forkhead Box O1 (FOXO1), a Terminal Selector Gene for Decidual Stromal Cell Identity
Molecular Biology and Evolution
2016
29
38
Noise reduction as an emergent property of single-cell aging
Nature Communications
2017
29
39
A High-Throughput Screen for Yeast Replicative Lifespan Identifies Lifespan-Extending Compounds
Cell Reports
2017
25
40
Surface densities prewet a near-critical membrane
Proceedings of the National Academy of Sciences of the United States of America
2021
24
41
Comparative Proteomics Enables Identification of Nonannotated Cold Shock Proteins in
E. coli
Journal of Proteome Research
2017
23
42
Single-cell analysis of prostaglandin E2-induced human decidual cell in vitro differentiation: a minimal ancestral deciduogenic signal
Biology of Reproduction
2022
23
43
Rapid propagation of membrane tension at retinal bipolar neuron presynaptic terminals
Science Advances
2022
22
44
F-actin cross-linking enhances the stability of force generation in disordered actomyosin networks
Computational Particle Mechanics
2015
21
45
Single-cell secretion analysis reveals a dual role for IL-10 in restraining and resolving the TLR4-induced inflammatory response
Cell Reports
2021
21
46
Alanyl-tRNA Synthetase Quality Control Prevents Global Dysregulation of the Escherichia coli Proteome
MBio
2019
20
47
The Coevolution of Placentation and Cancer
Annual Review of Animal Biosciences
2022
20
48
Balance between Force Generation and Relaxation Leads to Pulsed Contraction of Actomyosin Networks
Biophysical Journal
2018
18
49
Noise reduction facilitated by dosage compensation in gene networks
Nature Communications
2016
17
50
Evidence against tetrapod-wide digit identities and for a limited frame shift in bird wings
Nature Communications
2019
17
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