| # | Title | Journal | Year | Citations |
|---|
| 1 | COVID-19 infection: Emergence, transmission, and characteristics of human coronaviruses | Journal of Advanced Research | 2020 | 2,521 |
| 2 | Emerging coronaviruses: Genome structure, replication, and pathogenesis | Journal of Medical Virology | 2020 | 2,439 |
| 3 | Aerodynamic analysis of SARS-CoV-2 in two Wuhan hospitals | Nature | 2020 | 1,517 |
| 4 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 5 | Coronavirus infections and immune responses | Journal of Medical Virology | 2020 | 1,371 |
| 6 | The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation | Immunity | 2008 | 1,209 |
| 7 | Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients | Emerging Microbes and Infections | 2020 | 994 |
| 8 | Prominent changes in blood coagulation of patients with SARS-CoV-2 infection | Clinical Chemistry and Laboratory Medicine | 2020 | 942 |
| 9 | Mechanisms and regulation of cholesterol homeostasis | Nature Reviews Molecular Cell Biology | 2020 | 899 |
| 10 | Profiling serum cytokines in COVID-19 patients reveals IL-6 and IL-10 are disease severity predictors | Emerging Microbes and Infections | 2020 | 877 |
| 11 | Potentiating the antitumour response of CD8+ T cells by modulating cholesterol metabolism | Nature | 2016 | 648 |
| 12 | Broad host range of SARS-CoV-2 predicted by comparative and structural analysis of ACE2 in vertebrates | Proceedings of the National Academy of Sciences of the United States of America | 2020 | 517 |
| 13 | Direct Conversion of Fibroblasts to Neurons by Reprogramming PTB-Regulated MicroRNA Circuits | Cell | 2013 | 508 |
| 14 | The Histone Mark H3K36me3 Regulates Human DNA Mismatch Repair through Its Interaction with MutSα | Cell | 2013 | 504 |
| 15 | RNA based mNGS approach identifies a novel human coronavirus from two individual pneumonia cases in 2019 Wuhan outbreak | Emerging Microbes and Infections | 2020 | 471 |
| 16 | Identification and characterization of Bph14 , a gene conferring resistance to brown planthopper in rice | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 437 |
| 17 | Genome-wide Analysis of PTB-RNA Interactions Reveals a Strategy Used by the General Splicing Repressor to Modulate Exon Inclusion or Skipping | Molecular Cell | 2009 | 429 |
| 18 | Cholesterol metabolism in cancer: mechanisms and therapeutic opportunities | Nature Metabolism | 2020 | 411 |
| 19 | MicroRNA Directly Enhances Mitochondrial Translation during Muscle Differentiation | Cell | 2014 | 385 |
| 20 | The Ubiquitin Ligase RNF5 Regulates Antiviral Responses by Mediating Degradation of the Adaptor Protein MITA | Immunity | 2009 | 378 |
| 21 | Functional screen reveals SARS coronavirus nonstructural protein nsp14 as a novel cap N7 methyltransferase | Proceedings of the National Academy of Sciences of the United States of America | 2009 | 376 |
| 22 | Transcription factor AtMYB103 is required for anther development by regulating tapetum development, callose dissolution and exine formation in Arabidopsis | Plant Journal | 2007 | 339 |
| 23 | ddPCR: a more accurate tool for SARS-CoV-2 detection in low viral load specimens | Emerging Microbes and Infections | 2020 | 333 |
| 24 | Clinical Characteristics and Outcomes of Patients With Diabetes and COVID-19 in Association With Glucose-Lowering Medication | Diabetes Care | 2020 | 323 |
| 25 | Cholesterol Transport through Lysosome-Peroxisome Membrane Contacts | Cell | 2015 | 314 |
| 26 | TRIM32 Protein Modulates Type I Interferon Induction and Cellular Antiviral Response by Targeting MITA/STING Protein for K63-linked Ubiquitination | Journal of Biological Chemistry | 2012 | 313 |
| 27 | Ultrasmall Near-Infrared Ag2Se Quantum Dots with Tunable Fluorescence for in Vivo Imaging | Journal of the American Chemical Society | 2012 | 313 |
| 28 | Salt Stress Reduces Root Meristem Size by Nitric Oxide-Mediated Modulation of Auxin Accumulation and Signaling in Arabidopsis | Plant Physiology | 2015 | 310 |
| 29 | Chemical composition and antimicrobial activity of the essential oils of Chrysanthemum indicum | Journal of Ethnopharmacology | 2005 | 303 |
| 30 | Knockdown of Midgut Genes by dsRNA-Transgenic Plant-Mediated RNA Interference in the Hemipteran Insect Nilaparvata lugens | PLoS ONE | 2011 | 290 |
| 31 | TTDN1 is a Plk1-interacting protein involved in maintenance of cell cycle integrity | Cellular and Molecular Life Sciences | 2007 | 287 |
| 32 | Biochemical and Structural Insights into the Mechanisms of SARS Coronavirus RNA Ribose 2′-O-Methylation by nsp16/nsp10 Protein Complex | PLoS Pathogens | 2011 | 287 |
| 33 | SARS-CoV-2 N protein promotes NLRP3 inflammasome activation to induce hyperinflammation | Nature Communications | 2021 | 281 |
| 34 | SR Proteins Collaborate with 7SK and Promoter-Associated Nascent RNA to Release Paused Polymerase | Cell | 2013 | 279 |
| 35 | The metabolic ER stress sensor IRE1α suppresses alternative activation of macrophages and impairs energy expenditure in obesity | Nature Immunology | 2017 | 279 |
| 36 | Herbivore-Induced Callose Deposition on the Sieve Plates of Rice: An Important Mechanism for Host Resistance | Plant Physiology | 2008 | 266 |
| 37 | MIWI and piRNA-mediated cleavage of messenger RNAs in mouse testes | Cell Research | 2015 | 266 |
| 38 | R-ChIP Using Inactive RNase H Reveals Dynamic Coupling of R-loops with Transcriptional Pausing at Gene Promoters | Molecular Cell | 2017 | 263 |
| 39 | Human Telomeric DNA Forms Parallel-Stranded Intramolecular G-Quadruplex in K+ Solution under Molecular Crowding Condition | Journal of the American Chemical Society | 2007 | 261 |
| 40 | Genome-wide Analysis Reveals SR Protein Cooperation and Competition in Regulated Splicing | Molecular Cell | 2013 | 261 |
| 41 | The Rice Pentatricopeptide Repeat Protein RF5 Restores Fertility in Hong-Lian Cytoplasmic Male-Sterile Lines via a Complex with the Glycine-Rich Protein GRP162 | Plant Cell | 2012 | 260 |
| 42 | A triallelic system of S5 is a major regulator of the reproductive barrier and compatibility of indica–japonica hybrids in rice | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 257 |
| 43 | Sumoylation Promotes the Stability of the DNA Sensor cGAS and the Adaptor STING to Regulate the Kinetics of Response to DNA Virus | Immunity | 2016 | 256 |
| 44 | The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer’s disease | Journal of Neurochemistry | 2009 | 245 |
| 45 | NLRC3, a Member of the NLR Family of Proteins, Is a Negative Regulator of Innate Immune Signaling Induced by the DNA Sensor STING | Immunity | 2014 | 245 |
| 46 | Genome sequence of Gossypium herbaceum and genome updates of Gossypium arboreum and Gossypium hirsutum provide insights into cotton A-genome evolution | Nature Genetics | 2020 | 240 |
| 47 | Guidelines for Genome-Scale Analysis of Biological Rhythms | Journal of Biological Rhythms | 2017 | 237 |
| 48 | Abnormal mitochondrial dynamics and neurodegenerative diseases | Biochimica Et Biophysica Acta - Molecular Basis of Disease | 2010 | 229 |
| 49 | Rice UDP-Glucose Pyrophosphorylase1 Is Essential for Pollen Callose Deposition and Its Cosuppression Results in a New Type of Thermosensitive Genic Male Sterility | Plant Cell | 2007 | 219 |
| 50 | Physicochemical characterization and antioxidant activity of quercetin‐loaded chitosan nanoparticles | Journal of Applied Polymer Science | 2008 | 218 |
