| # | Title | Journal | Year | Citations |
|---|
| 1 | Thymus and activation-regulated chemokine in atopic dermatitis: Serum thymus and activation-regulated chemokine level is closely related with disease activity | Journal of Allergy and Clinical Immunology | 2001 | 504 |
| 2 | Connective Tissue Growth Factor Gene Expression in Tissue Sections From Localized Scleroderma, Keloid, and Other Fibrotic Skin Disorders | Journal of Investigative Dermatology | 1996 | 402 |
| 3 | Characterization of SIS3, a Novel Specific Inhibitor of Smad3, and Its Effect on Transforming Growth Factor-β1-Induced Extracellular Matrix Expression | Molecular Pharmacology | 2006 | 390 |
| 4 | Common and Distinct Clinical Features in Adult Patients with Anti-Aminoacyl-tRNA Synthetase Antibodies: Heterogeneity within the Syndrome | PLoS ONE | 2013 | 306 |
| 5 | Pathogenesis of fibrosis: role of TGF-β and CTGF | Current Opinion in Rheumatology | 2002 | 290 |
| 6 | Regulatory B Cells (B10 Cells) Have a Suppressive Role in Murine Lupus: CD19 and B10 Cell Deficiency Exacerbates Systemic Autoimmunity | Journal of Immunology | 2010 | 274 |
| 7 | Significant Correlation Between Connective Tissue Growth Factor Gene Expression and Skin Sclerosis in Tissue Sections from Patients with Systemic Sclerosis | Journal of Investigative Dermatology | 1995 | 253 |
| 8 | Matrix/Integrin Interaction Activates the Mitogen-activated Protein Kinase, p44erk-1 and p42erk-2 | Journal of Biological Chemistry | 1995 | 237 |
| 9 | Estrogen enhances immunoglobulin production by human PBMCs | Journal of Allergy and Clinical Immunology | 1999 | 234 |
| 10 | Thymus and activation regulated chemokine (TARC)/CCL17 and skin diseases | Journal of Dermatological Science | 2006 | 233 |
| 11 | Guidelines for management of atopic dermatitis | Journal of Dermatology | 2009 | 215 |
| 12 | Testosterone inhibits immunoglobulin production by human peripheral blood mononuclear cells | Clinical and Experimental Immunology | 1996 | 213 |
| 13 | Increased Expression of Integrin αvβ3 Contributes to the Establishment of Autocrine TGF-β Signaling in Scleroderma Fibroblasts | Journal of Immunology | 2005 | 207 |
| 14 | Impaired Smad7-Smurf–mediated negative regulation of TGF-β signaling in scleroderma fibroblasts | Journal of Clinical Investigation | 2004 | 181 |
| 15 | Acquired, bilateral nevus of Ota-like macules | Journal of the American Academy of Dermatology | 1984 | 179 |
| 16 | Blockade of endogenous transforming growth factor ? signaling prevents up-regulated collagen synthesis in scleroderma fibroblasts: Association with increased expression of transforming growth factor ? receptors | Arthritis and Rheumatism | 2001 | 175 |
| 17 | Interleukin-12 p40 gene (IL12B) 3′-untranslated region polymorphism is associated with susceptibility to atopic dermatitis and psoriasis vulgaris | Journal of Dermatological Science | 2002 | 173 |
| 18 | IL-10–Producing Regulatory B10 Cells Inhibit Intestinal Injury in a Mouse Model | American Journal of Pathology | 2011 | 172 |
| 19 | Increased Expression of Integrin αvβ5 Induces the Myofibroblastic Differentiation of Dermal Fibroblasts | American Journal of Pathology | 2006 | 159 |
| 20 | Mutations in the rod domain of keratin 2e in patients with ichthyosis bullosa of Siemens | Nature Genetics | 1994 | 153 |
| 21 | Antihistone antibodies in patients with localized scleroderma | Arthritis and Rheumatism | 1993 | 150 |
| 22 | The role of IL-22 and Th22 cells in human skin diseases | Journal of Dermatological Science | 2013 | 147 |
| 23 | Mechanical Stretching In Vitro Regulates Signal Transduction Pathways and Cellular Proliferation in Human Epidermal Keratinocytes | Journal of Investigative Dermatology | 2004 | 143 |
| 24 | Thymus and activation-regulated chemokine (TARC/CCL17) in mycosis fungoides: Serum TARC levels reflect the disease activity of mycosis fungoides | Journal of the American Academy of Dermatology | 2003 | 142 |
| 25 | Increased serum cutaneous T cell-attracting chemokine (CCL27) levels in patients with atopic dermatitis and psoriasis vulgaris | Journal of Allergy and Clinical Immunology | 2003 | 139 |
| 26 | Serum macrophage-derived chemokine (MDC) levels are closely related with the disease activity of atopic dermatitis | Clinical and Experimental Immunology | 2002 | 134 |
| 27 | Disease-associated CIAS1 mutations induce monocyte death, revealing low-level mosaicism in mutation-negative cryopyrin-associated periodic syndrome patients | Blood | 2008 | 134 |
| 28 | Interplay between CXCR2 and BLT1 Facilitates Neutrophil Infiltration and Resultant Keratinocyte Activation in a Murine Model of Imiquimod-Induced Psoriasis | Journal of Immunology | 2014 | 132 |
| 29 | Adiponectin Regulates Cutaneous Wound Healing by Promoting Keratinocyte Proliferation and Migration via the ERK Signaling Pathway | Journal of Immunology | 2012 | 131 |
| 30 | Altered B lymphocyte function induces systemic autoimmunity in systemic sclerosis | Molecular Immunology | 2004 | 123 |
| 31 | Tenascin-C upregulation by transforming growth factor-β in human dermal fibroblasts involves Smad3, Sp1, and Ets1 | Oncogene | 2004 | 120 |
| 32 | Epidemiological study of patients with systemic sclerosis in Tokyo | Archives of Dermatological Research | 1991 | 117 |
| 33 | Serum IL-33 levels are raised in patients with systemic sclerosis: association with extent of skin sclerosis and severity of pulmonary fibrosis | Clinical Rheumatology | 2011 | 116 |
| 34 | Demonstration of interleukin-2, interleukin-4 and interleukin-6 in sera from patients with localized scleroderma | Archives of Dermatological Research | 1995 | 112 |
| 35 | Antihistone Antibodies in Systemic Sclerosis | Arthritis and Rheumatism | 1994 | 110 |
| 36 | LPA4 regulates blood and lymphatic vessel formation during mouse embryogenesis | Blood | 2010 | 109 |
| 37 | CD19 Expression in B Cells Is Important for Suppression of Contact Hypersensitivity | American Journal of Pathology | 2007 | 107 |
| 38 | Antagonistic Effects of TNF-α on TGF-β Signaling Through Down-Regulation of TGF-β Receptor Type II in Human Dermal Fibroblasts | Journal of Immunology | 2003 | 104 |
| 39 | Elevated levels of eotaxin and interleukin-5 in blister fluid of bullous pemphigoid: correlation with tissue eosinophilia | British Journal of Dermatology | 2000 | 103 |
| 40 | Significant elevation of serum levels of eotaxin-3/CCL26, but not of eotaxin-2/CCL24, in patients with atopic dermatitis: serum eotaxin-3/CCL26 levels reflect the disease activity of atopic dermatitis | Clinical and Experimental Immunology | 2003 | 98 |
| 41 | Future treatments in systemic sclerosis | Journal of Dermatology | 2010 | 98 |
| 42 | Global patterns of care in advanced stage mycosis fungoides/Sezary syndrome: a multicenter retrospective follow-up study from the Cutaneous Lymphoma International Consortium | Annals of Oncology | 2017 | 98 |
| 43 | Serum concentrations of vascular endothelial growth factor in collagen diseases | British Journal of Dermatology | 1998 | 96 |
| 44 | The Repeat Domain of the Melanosomal Matrix Protein PMEL17/GP100 Is Required for the Formation of Organellar Fibers | Journal of Biological Chemistry | 2006 | 96 |
| 45 | Anti-PD1 checkpoint inhibitor therapy in acral melanoma: a multicenter study of 193 Japanese patients | Annals of Oncology | 2020 | 96 |
| 46 | Promoter methylation profiling of 30 genes in human malignant melanoma | Cancer Science | 2004 | 95 |
| 47 | Chemoradiotherapy with taxane is superior to conventional surgery and radiotherapy in the management of cutaneous angiosarcoma: a multicentre, retrospective study | British Journal of Dermatology | 2014 | 93 |
| 48 | Tissue Inhibitor of Metalloproteinase 1 (TIMP-1) May Be an Autocrine Growth Factor in Scleroderma Fibroblasts. | Journal of Investigative Dermatology | 1997 | 91 |
| 49 | Novel Mechanism of Steroid Action in Skin through Glucocorticoid Receptor Monomers | Molecular and Cellular Biology | 2000 | 91 |
| 50 | Glycoprotein nonmetastatic melanoma protein b, a melanocytic cell marker, is a melanosome‐specific and proteolytically released protein | FASEB Journal | 2010 | 91 |
