| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 2 | 2013 Classification Criteria for Systemic Sclerosis: An American College of Rheumatology/European League Against Rheumatism Collaborative Initiative | Arthritis and Rheumatism | 2013 | 2,359 |
| 3 | Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017 | JAMA Oncology | 2019 | 1,691 |
| 4 | Probability of stroke: a risk profile from the Framingham Study. | Stroke | 1991 | 1,589 |
| 5 | Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation | Nature | 1995 | 1,485 |
| 6 | The clinical implications of endothelial dysfunction | Journal of the American College of Cardiology | 2003 | 1,444 |
| 7 | Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes | Nature Medicine | 2018 | 1,224 |
| 8 | Definition of organ involvement and treatment response in immunoglobulin light chain amyloidosis (AL): A consensus opinion from the 10th International Symposium on Amyloid and Amyloidosis | American Journal of Hematology | 2005 | 1,179 |
| 9 | 50 year trends in atrial fibrillation prevalence, incidence, risk factors, and mortality in the Framingham Heart Study: a cohort study | Lancet, The | 2015 | 1,148 |
| 10 | Wound bed preparation: a systematic approach to wound management | Wound Repair and Regeneration | 2003 | 1,045 |
| 11 | The Framingham Heart Study and the epidemiology of cardiovascular disease: a historical perspective | Lancet, The | 2014 | 1,024 |
| 12 | Measures of knee function: International Knee Documentation Committee (IKDC) Subjective Knee Evaluation Form, Knee Injury and Osteoarthritis Outcome Score (KOOS), Knee Injury and Osteoarthritis Outcome Score Physical Function Short Form (KOOS‐PS), Knee Outcome Survey Activities of Daily Living Scale (KOS‐ADL), Lysholm Knee Scoring Scale, Oxford Knee Score (OKS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Activity Rating Scale (ARS), and Tegner Activity Score (TAS) | Arthritis Care and Research | 2011 | 897 |
| 13 | Dose-response associations between accelerometry measured physical activity and sedentary time and all cause mortality: systematic review and harmonised meta-analysis | BMJ: British Medical Journal | 2019 | 856 |
| 14 | AIMS2. The Content and Properties of a Revised and Expanded Arthritis Impact Measurement Scales Health Status Questionnaire | Arthritis and Rheumatism | 1992 | 816 |
| 15 | Incidence of symptomatic hand, hip, and knee osteoarthritis among patients in a health maintenance organization | Arthritis and Rheumatism | 1995 | 736 |
| 16 | Risk Stratification for Postoperative Cardiovascular Events via Noninvasive Assessment of Endothelial Function | Circulation | 2002 | 726 |
| 17 | Effect of Clopidogrel on Early Failure of Arteriovenous Fistulas for Hemodialysis | JAMA - Journal of the American Medical Association | 2008 | 700 |
| 18 | Plasma oxytocin levels in autistic children | Biological Psychiatry | 1998 | 696 |
| 19 | Adverse Events Associated With Testosterone Replacement in Middle-Aged and Older Men: A Meta-Analysis of Randomized, Placebo-Controlled Trials | Journals of Gerontology - Series A Biological Sciences and Medical Sciences | 2005 | 635 |
| 20 | Sex differences in human adipose tissues – the biology of pear shape | Biology of Sex Differences | 2012 | 626 |
| 21 | The Lifetime Risk of Stroke | Stroke | 2006 | 614 |
| 22 | Cross-Sectional Relations of Digital Vascular Function to Cardiovascular Risk Factors in the Framingham Heart Study | Circulation | 2008 | 607 |
| 23 | Adipose tissue heterogeneity: Implication of depot differences in adipose tissue for obesity complications | Molecular Aspects of Medicine | 2013 | 590 |
| 24 | Induction of Peroxisome Proliferator-Activated Receptor γ during the Conversion of 3T3 Fibroblasts into Adipocytes Is Mediated by C/EBPβ, C/EBPδ, and Glucocorticoids | Molecular and Cellular Biology | 1996 | 553 |
| 25 | Anatomical Differences in the Mirror Neuron System and Social Cognition Network in Autism | Cerebral Cortex | 2006 | 549 |
| 26 | Neuropsychological Criteria for Mild Cognitive Impairment Improves Diagnostic Precision, Biomarker Associations, and Progression Rates | Journal of Alzheimer's Disease | 2014 | 493 |
| 27 | Conditional ectopic expression of C/EBP beta in NIH-3T3 cells induces PPAR gamma and stimulates adipogenesis. | Genes and Development | 1995 | 483 |
| 28 | The Alzheimer's Disease Neuroimaging Initiative: Progress report and future plans | Alzheimer's and Dementia | 2010 | 443 |
| 29 | Violence during pregnancy and substance use. | American Journal of Public Health | 1990 | 442 |
| 30 | Trends in Incidence, Lifetime Risk, Severity, and 30-Day Mortality of Stroke Over the Past 50 Years | JAMA - Journal of the American Medical Association | 2006 | 425 |
| 31 | Factors predicting response to treatment in rheumatoid arthritis: The importance of disease duration | Arthritis and Rheumatism | 2000 | 421 |
| 32 | Recombinant human anti–transforming growth factor β1 antibody therapy in systemic sclerosis: A multicenter, randomized, placebo-controlled phase I/II trial of CAT-192 | Arthritis and Rheumatism | 2007 | 415 |
| 33 | Transforming growth factor beta (TGF‐β) isoforms in wound healing and fibrosis | Wound Repair and Regeneration | 2016 | 395 |
| 34 | 2015 Gout Classification Criteria: An American College of Rheumatology/European League Against Rheumatism Collaborative Initiative | Arthritis and Rheumatology | 2015 | 393 |
| 35 | Correlation of the development of knee pain with enlarging bone marrow lesions on magnetic resonance imaging | Arthritis and Rheumatism | 2007 | 392 |
| 36 | Distinctions Between Diagnostic and Classification Criteria? | Arthritis Care and Research | 2015 | 386 |
| 37 | The causal pathways linking health literacy to health outcomes | American Journal of Health Behavior | 2007 | 386 |
| 38 | Targeting Plasmodium PI(4)K to eliminate malaria | Nature | 2013 | 377 |
| 39 | The insulin receptor: structure, function, and signaling | American Journal of Physiology - Cell Physiology | 1994 | 364 |
| 40 | Nutrients Suppress Phosphatidylinositol 3-Kinase/Akt Signaling via Raptor-Dependent mTOR-Mediated Insulin Receptor Substrate 1 Phosphorylation | Molecular and Cellular Biology | 2006 | 362 |
| 41 | Cardiovascular side effects of cancer therapies: a position statement from the Heart Failure Association of the European Society of Cardiology | European Journal of Heart Failure | 2011 | 350 |
| 42 | Determination of Brain Death/Death by Neurologic Criteria | JAMA - Journal of the American Medical Association | 2020 | 346 |
| 43 | Use of Sunscreen, Sunburning Rates, and Tanning Bed Use Among More Than 10 000 US Children and Adolescents | Pediatrics | 2002 | 339 |
| 44 | Primary Care Validation of a Single-Question Alcohol Screening Test | Journal of General Internal Medicine | 2009 | 330 |
| 45 | Relation of Brachial and Digital Measures of Vascular Function in the Community | Hypertension | 2011 | 330 |
| 46 | General Cortical and Special Prefrontal Connections: Principles from Structure to Function | Annual Review of Neuroscience | 2015 | 328 |
| 47 | Inverse association between cancer and Alzheimer's disease: results from the Framingham Heart Study | BMJ: British Medical Journal | 2012 | 324 |
| 48 | Sepsis: Multiple Abnormalities, Heterogeneous Responses, and Evolving Understanding | Physiological Reviews | 2013 | 324 |
| 49 | RELATION BETWEEN SMOKING AND AGE OF NATURAL MENOPAUSE | Lancet, The | 1977 | 320 |
| 50 | Elevated glucose promotes generation of endothelium-derived vasoconstrictor prostanoids in rabbit aorta. | Journal of Clinical Investigation | 1990 | 320 |
