Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease | Neuron | 2006 | 950 |
Obesity-associated improvements in metabolic profile through expansion of adipose tissue | Journal of Clinical Investigation | 2007 | 938 |
Selective ablation of proliferating microglial cells exacerbates ischemic injury in the brain | Journal of Neuroscience | 2007 | 700 |
Regulation of innate immune responses in the brain | Nature Reviews Immunology | 2009 | 618 |
Cardiovascular risk and events in 17 low-, middle-, and high-income countries | New England Journal of Medicine | 2014 | 499 |
Two isoforms of glutamate decarboxylase: why? | Trends in Pharmacological Sciences | 1998 | 492 |
Stem and progenitor cells in skeletal muscle development, maintenance, and therapy | Molecular Therapy | 2007 | 471 |
A transgenic mouse with a deletion in the collagenous domain of adiponectin displays elevated circulating adiponectin and improved insulin sensitivity | Endocrinology | 2004 | 436 |
Increased activation of the mammalian target of rapamycin pathway in liver and skeletal muscle of obese rats: possible involvement in obesity-linked insulin resistance | Endocrinology | 2005 | 427 |
Proinflammatory cytokine synthesis in the injured mouse spinal cord: multiphasic expression pattern and identification of the cell types involved | Journal of Comparative Neurology | 2007 | 416 |
Targeted disruption of inducible nitric oxide synthase protects against obesity-linked insulin resistance in muscle | Nature Medicine | 2001 | 414 |
Toll-like receptor 4: the missing link of the cerebral innate immune response triggered by circulating gram-negative bacterial cell wall components | FASEB Journal | 2001 | 411 |
Amino acid and insulin signaling via the mTOR/p70 S6 kinase pathway. A negative feedback mechanism leading to insulin resistance in skeletal muscle cells | Journal of Biological Chemistry | 2001 | 407 |
Pleasure: the common currency | Journal of Theoretical Biology | 1992 | 400 |
Chemokine expression by glial cells directs leukocytes to sites of axonal injury in the CNS | Journal of Neuroscience | 2003 | 388 |
Molecular insights on the cerebral innate immune system | Brain, Behavior, and Immunity | 2003 | 345 |
Identification of IRS-1 Ser-1101 as a target of S6K1 in nutrient- and obesity-induced insulin resistance | Proceedings of the National Academy of Sciences of the United States of America | 2007 | 336 |
Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis | Nature Neuroscience | 2006 | 327 |
Activation of PKC-delta and SHP-1 by hyperglycemia causes vascular cell apoptosis and diabetic retinopathy | Nature Medicine | 2009 | 308 |
Ionic mechanisms underlying synchronized oscillations and propagating waves in a model of ferret thalamic slices | Journal of Neurophysiology | 1996 | 296 |
Bone marrow stem cells have the ability to populate the entire central nervous system into fully differentiated parenchymal microglia | FASEB Journal | 2004 | 289 |
Overactivation of S6 kinase 1 as a cause of human insulin resistance during increased amino acid availability | Diabetes | 2005 | 288 |
Poly(ADP-ribose) (PAR) binding to apoptosis-inducing factor is critical for PAR polymerase-1-dependent cell death (parthanatos) | Science Signaling | 2011 | 286 |
Circulating endocannabinoid levels, abdominal adiposity and related cardiometabolic risk factors in obese men | International Journal of Obesity | 2007 | 282 |
Comparative gene expression analysis of blood and brain provides concurrent validation of SELENBP1 up-regulation in schizophrenia | Proceedings of the National Academy of Sciences of the United States of America | 2005 | 271 |