| # | Title | Journal | Year | Citations |
|---|
| 1 | The Immune Landscape of Cancer | Immunity | 2018 | 3,706 |
| 2 | Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017 | JAMA Oncology | 2019 | 1,691 |
| 3 | Metalloproteinases in biology and pathology of the nervous system | Nature Reviews Neuroscience | 2001 | 946 |
| 4 | Nivolumab plus ipilimumab versus sunitinib in first-line treatment for advanced renal cell carcinoma: extended follow-up of efficacy and safety results from a randomised, controlled, phase 3 trial | Lancet Oncology, The | 2019 | 594 |
| 5 | Mindfulness-based stress reduction in relation to quality of life, mood, symptoms of stress and levels of cortisol, dehydroepiandrosterone sulfate (DHEAS) and melatonin in breast and prostate cancer outpatients | Psychoneuroendocrinology | 2004 | 580 |
| 6 | Clinical practice guidelines on the evidence‐based use of integrative therapies during and after breast cancer treatment | Ca-A Cancer Journal for Clinicians | 2017 | 488 |
| 7 | Impact of mindfulness-based stress reduction (MBSR) on sleep, mood, stress and fatigue symptoms in cancer outpatients | International Journal of Behavioral Medicine | 2005 | 451 |
| 8 | Guidance on the use of bisphosphonates in solid tumours: recommendations of an international expert panel | Annals of Oncology | 2008 | 410 |
| 9 | Exploring self‐compassion and empathy in the context of mindfulness‐based stress reduction (MBSR) | Stress and Health | 2010 | 410 |
| 10 | Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas | Cancer Cell | 2018 | 396 |
| 11 | REAP: A two minute cell fractionation method | BMC Research Notes | 2010 | 389 |
| 12 | The report of Task Group 100 of the AAPM: Application of risk analysis methods to radiation therapy quality management | Medical Physics | 2016 | 352 |
| 13 | Quality of life in brain tumor patients: the relative contributions of depression, fatigue, emotional distress, and existential issues | Journal of Neuro-Oncology | 2002 | 305 |
| 14 | Cancer distress screening | Journal of Psychosomatic Research | 2003 | 304 |
| 15 | The SPFH domain-containing proteins: more than lipid raft markers | Trends in Cell Biology | 2007 | 303 |
| 16 | Tremelimumab plus Durvalumab in Unresectable Hepatocellular Carcinoma | | 2022 | 298 |
| 17 | Contemplative/emotion training reduces negative emotional behavior and promotes prosocial responses. | Emotion | 2012 | 283 |
| 18 | Emotional distress: the sixth vital sign—future directions in cancer care | Psycho-Oncology | 2006 | 272 |
| 19 | Sympathy, empathy, and compassion: A grounded theory study of palliative care patients’ understandings, experiences, and preferences | Palliative Medicine | 2017 | 272 |
| 20 | Compassion: a scoping review of the healthcare literature | BMC Palliative Care | 2016 | 268 |
| 21 | Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort | Lancet Oncology, The | 2018 | 268 |
| 22 | Dose-Response Association of CD8+ Tumor-Infiltrating Lymphocytes and Survival Time in High-Grade Serous Ovarian Cancer | JAMA Oncology | 2017 | 260 |
| 23 | A systematic review and meta-analysis of randomized controlled trials of cognitive behavior therapy for insomnia (CBT-I) in cancer survivors | Sleep Medicine Reviews | 2016 | 250 |
| 24 | Management of Bleeding in Patients with Advanced Cancer | Oncologist | 2004 | 249 |
| 25 | A Phase I Trial of Intratumoral Administration of Reovirus in Patients With Histologically Confirmed Recurrent Malignant Gliomas | Molecular Therapy | 2008 | 243 |
| 26 | Mutation of the calcium channel gene Cacna1f disrupts calcium signaling, synaptic transmission and cellular organization in mouse retina | Human Molecular Genetics | 2005 | 235 |
| 27 | Phase 3 randomized, open-label, multicenter study of tremelimumab (T) and durvalumab (D) as first-line therapy in patients (pts) with unresectable hepatocellular carcinoma (uHCC): HIMALAYA. | Journal of Clinical Oncology | 2022 | 235 |
| 28 | Efficacy and medical cost offset of psychosocial interventions in cancer care: Making the case for economic analyses | Psycho-Oncology | 2004 | 233 |
| 29 | PTEN functions to 'prioritize' chemotactic cues and prevent 'distraction' in migrating neutrophils | Nature Immunology | 2008 | 229 |
| 30 | Emotional Distress: The Sixth Vital Sign in Cancer Care | Journal of Clinical Oncology | 2005 | 228 |
| 31 | The worldwide incidence and prevalence of primary brain tumors: a systematic review and meta-analysis | Neuro-Oncology | 2015 | 228 |
| 32 | Matrix Metalloproteinase-9 Facilitates Remyelination in Part by Processing the Inhibitory NG2 Proteoglycan | Journal of Neuroscience | 2003 | 228 |
| 33 | Lipid rafts and little caves | FEBS Journal | 2002 | 215 |
| 34 | Clinical Practice Guidelines on the Use of Integrative Therapies as Supportive Care in Patients Treated for Breast Cancer | Journal of the National Cancer Institute Monographs | 2014 | 207 |
| 35 | Vulnerability of Human Neurons to T Cell-Mediated Cytotoxicity | Journal of Immunology | 2003 | 198 |
| 36 | Differential In situ cytokine profiles of Langerhans-like cells and T cells in Langerhans cell histiocytosis: abundant expression of cytokines relevant to disease and treatment | Blood | 1999 | 189 |
| 37 | A non-randomized comparison of mindfulness-based stress reduction and healing arts programs for facilitating post-traumatic growth and spirituality in cancer outpatients | Supportive Care in Cancer | 2007 | 187 |
| 38 | Real-world data: towards achieving the achievable in cancer care | Nature Reviews Clinical Oncology | 2019 | 187 |
| 39 | Interleukin-1 is a key regulator of matrix metalloproteinase-9 expression in human neurons in culture and following mouse brain trauma in vivo | Journal of Neuroscience Research | 2000 | 173 |
| 40 | Meta-analysis in metastatic uveal melanoma to determine progression free and overall survival benchmarks: an international rare cancers initiative (IRCI) ocular melanoma study | Annals of Oncology | 2019 | 171 |
| 41 | Physical activity for men receiving androgen deprivation therapy for prostate cancer: benefits from a 16-week intervention | Supportive Care in Cancer | 2010 | 170 |
| 42 | Exploitation of Astrocytes by Glioma Cells to Facilitate Invasiveness: A Mechanism Involving Matrix Metalloproteinase-2 and the Urokinase-Type Plasminogen Activator–Plasmin Cascade | Journal of Neuroscience | 2003 | 163 |
| 43 | Sleeping well with cancer: a systematic review of cognitive behavioral therapy for insomnia in cancer patients | Neuropsychiatric Disease and Treatment | 2014 | 161 |
| 44 | Implementation of Enhanced Recovery After Surgery (ERAS) Across a Provincial Healthcare System: The ERAS Alberta Colorectal Surgery Experience | World Journal of Surgery | 2016 | 159 |
| 45 | The Anchoring Protein RACK1 Links Protein Kinase Cε to Integrin β Chains | Journal of Biological Chemistry | 2002 | 157 |
| 46 | Benefits of psychosocial oncology care: improved quality of life and medical cost offset | Health and Quality of Life Outcomes | 2003 | 154 |
| 47 | Nab-paclitaxel plus gemcitabine in patients with locally advanced pancreatic cancer (LAPACT): a multicentre, open-label phase 2 study | The Lancet Gastroenterology and Hepatology | 2020 | 152 |
| 48 | Safety and efficacy of nivolumab in combination with sunitinib or pazopanib in advanced or metastatic renal cell carcinoma: the CheckMate 016 study | | 2018 | 151 |
| 49 | The p75 Neurotrophin Receptor Is a Central Regulator of Glioma Invasion | PLoS Biology | 2007 | 150 |
| 50 | A randomized controlled trial of a brief psychoeducational support group for partners of early stage breast cancer patients | Psycho-Oncology | 2000 | 148 |
