| # | Title | Journal | Year | Citations |
|---|
| 1 | A blood RNA signature for tuberculosis disease risk: a prospective cohort study | Lancet, The | 2016 | 678 |
| 2 | Evolutionary history and global spread of the Mycobacterium tuberculosis Beijing lineage | Nature Genetics | 2015 | 466 |
| 3 | The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis | Lancet Respiratory Medicine,the | 2017 | 459 |
| 4 | Immunological biomarkers of tuberculosis | Nature Reviews Immunology | 2011 | 455 |
| 5 | Bioactive Compounds and Biological Functions of Garlic (Allium sativum L.) | Foods | 2019 | 399 |
| 6 | Genomic analysis identifies targets of convergent positive selection in drug-resistant Mycobacterium tuberculosis | Nature Genetics | 2013 | 393 |
| 7 | Evolution and expansion of the Mycobacterium tuberculosis PE and PPE multigene families and their association with the duplication of the ESAT-6 (esx) gene cluster regions | BMC Evolutionary Biology | 2006 | 388 |
| 8 | Genital Inflammation and the Risk of HIV Acquisition in Women | Clinical Infectious Diseases | 2015 | 354 |
| 9 | Association of LRRK2 exonic variants with susceptibility to Parkinson's disease: a case–control study | Lancet Neurology, The | 2011 | 294 |
| 10 | Human gene expression profiles of susceptibility and resistance in tuberculosis | Genes and Immunity | 2011 | 288 |
| 11 | A standardised method for interpreting the association between mutations and phenotypic drug resistance inMycobacterium tuberculosis | European Respiratory Journal | 2017 | 273 |
| 12 | Genome-wide analysis of multi- and extensively drug-resistant Mycobacterium tuberculosis | Nature Genetics | 2018 | 271 |
| 13 | The X chromosome and sex-specific effects in infectious disease susceptibility | Human Genomics | 2019 | 271 |
| 14 | A Dose-Ranging Trial to Optimize the Dose of Rifampin in the Treatment of Tuberculosis | American Journal of Respiratory and Critical Care Medicine | 2015 | 260 |
| 15 | Mycobacterium bovis at the animal–human interface: A problem, or not? | Veterinary Microbiology | 2010 | 248 |
| 16 | Global control of tuberculosis: from extensively drug-resistant to untreatable tuberculosis | Lancet Respiratory Medicine,the | 2014 | 237 |
| 17 | Whole genome sequencing of Mycobacterium tuberculosis: current standards and open issues | Nature Reviews Microbiology | 2019 | 237 |
| 18 | PPE and PE_PGRS proteins of Mycobacterium marinum are transported via the type VII secretion system ESX‐5 | Molecular Microbiology | 2009 | 233 |
| 19 | Toxic Metal Implications on Agricultural Soils, Plants, Animals, Aquatic life and Human Health | International Journal of Environmental Research and Public Health | 2020 | 225 |
| 20 | Distinct Phases of Blood Gene Expression Pattern Through Tuberculosis Treatment Reflect Modulation of the Humoral Immune Response | Journal of Infectious Diseases | 2013 | 218 |
| 21 | Four-Gene Pan-African Blood Signature Predicts Progression to Tuberculosis | American Journal of Respiratory and Critical Care Medicine | 2018 | 217 |
| 22 | A Balancing Act: Efflux/Influx in Mycobacterial Drug Resistance | Antimicrobial Agents and Chemotherapy | 2009 | 212 |
| 23 | Long-term outcomes of patients with extensively drug-resistant tuberculosis in South Africa: a cohort study | Lancet, The | 2014 | 211 |
| 24 | Phylogeny to function: PE/PPE protein evolution and impact on Mycobacterium tuberculosis pathogenicity | Molecular Microbiology | 2015 | 198 |
| 25 | Antioxidant effects of curcumin in models of neurodegeneration, aging, oxidative and nitrosative stress: A review | Neuroscience | 2019 | 194 |
| 26 | Whole-genome sequencing to establish relapse or re-infection with Mycobacterium tuberculosis: a retrospective observational study | Lancet Respiratory Medicine,the | 2013 | 184 |
| 27 | Putative Compensatory Mutations in the rpoC Gene of Rifampin-Resistant Mycobacterium tuberculosis Are Associated with Ongoing Transmission | Antimicrobial Agents and Chemotherapy | 2013 | 184 |
| 28 | Mixed-Strain Mycobacterium tuberculosis Infections and the Implications for Tuberculosis Treatment and Control | Clinical Microbiology Reviews | 2012 | 172 |
| 29 | COVID-19 cough classification using machine learning and global smartphone recordings | Computers in Biology and Medicine | 2021 | 171 |
| 30 | The South African Tuberculosis Care Cascade: Estimated Losses and Methodological Challenges | Journal of Infectious Diseases | 2017 | 170 |
| 31 | The human immune response to tuberculosis and its treatment: a view from the blood | Immunological Reviews | 2015 | 168 |
| 32 | Brain-Derived Neurotrophic Factor (BDNF) protein levels in anxiety disorders: systematic review and meta-regression analysis | Frontiers in Integrative Neuroscience | 2013 | 166 |
| 33 | Rifampicin Reduces Susceptibility to Ofloxacin in Rifampicin-resistant Mycobacterium tuberculosis through Efflux | American Journal of Respiratory and Critical Care Medicine | 2011 | 149 |
| 34 | A New Phylogenetic Framework for the Animal-Adapted Mycobacterium tuberculosis Complex | Frontiers in Microbiology | 2018 | 145 |
| 35 | An Unexpectedly Complex Architecture for Skin Pigmentation in Africans | Cell | 2017 | 134 |
| 36 | Genetic Determinants of Drug Resistance in Mycobacterium tuberculosis and Their Diagnostic Value | American Journal of Respiratory and Critical Care Medicine | 2016 | 131 |
| 37 | Drug-Penetration Gradients Associated with Acquired Drug Resistance in Patients with Tuberculosis | American Journal of Respiratory and Critical Care Medicine | 2018 | 130 |
| 38 | Metabolite changes in blood predict the onset of tuberculosis | Nature Communications | 2018 | 129 |
| 39 | Optimization and Interpretation of Serial QuantiFERON Testing to Measure Acquisition of Mycobacterium tuberculosis Infection | American Journal of Respiratory and Critical Care Medicine | 2017 | 124 |
| 40 | Development of a Novel Lead that Targets M. tuberculosis Polyketide Synthase 13 | Cell | 2017 | 124 |
| 41 | Systematic review of mutations associated with resistance to the new and repurposedMycobacterium tuberculosisdrugs bedaquiline, clofazimine, linezolid, delamanid and pretomanid | Journal of Antimicrobial Chemotherapy | 2020 | 124 |
| 42 | Mutation rate and the emergence of drug resistance in Mycobacterium tuberculosis | Journal of Antimicrobial Chemotherapy | 2014 | 123 |
| 43 | Impact of Nonlinear Interactions of Pharmacokinetics and MICs on Sputum Bacillary Kill Rates as a Marker of Sterilizing Effect in Tuberculosis | Antimicrobial Agents and Chemotherapy | 2015 | 123 |
| 44 | Efflux pump inhibitors: targeting mycobacterial efflux systems to enhance TB therapy | Journal of Antimicrobial Chemotherapy | 2016 | 123 |
| 45 | The Temporal Dynamics of Relapse and Reinfection Tuberculosis After Successful Treatment: A Retrospective Cohort Study | Clinical Infectious Diseases | 2014 | 119 |
| 46 | Therapeutic host-directed strategies to improve outcome in tuberculosis | Mucosal Immunology | 2020 | 117 |
| 47 | Xpert MTB/RIF Results in Patients With Previous Tuberculosis: Can We Distinguish True From False Positive Results? | Clinical Infectious Diseases | 2016 | 112 |
| 48 | Safety and Immunogenicity of the Recombinant Mycobacterium bovis BCG Vaccine VPM1002 in HIV-Unexposed Newborn Infants in South Africa | Vaccine Journal | 2017 | 112 |
| 49 | Mutations in ppe38 block PE_PGRS secretion and increase virulence of Mycobacterium tuberculosis | Nature Microbiology | 2018 | 112 |
| 50 | Energy Metabolism and Drug Efflux in Mycobacterium tuberculosis | Antimicrobial Agents and Chemotherapy | 2014 | 109 |
