1.1K(top 0.1%)
papers
49.7K(top 0.1%)
citations
108(top 0.1%)
h-index
170(top 0.1%)
g-index
1.2K
all documents
53.5K
doc citations
4.3K
citing journals

Top Articles

#TitleJournalYearCitations
1DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune responseNature20071,437
2Oncogenic mechanisms of the Helicobacter pylori CagA proteinNature Reviews Cancer2004660
3Tumor-infiltrating DCs suppress nucleic acid–mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1Nature Immunology2012649
4Transgenic expression of Helicobacter pylori CagA induces gastrointestinal and hematopoietic neoplasms in mouseProceedings of the National Academy of Sciences of the United States of America2008525
5Biological activity of the Helicobacter pylori virulence factor CagA is determined by variation in the tyrosine phosphorylation sitesProceedings of the National Academy of Sciences of the United States of America2002522
6The oestrogen receptor alpha-regulated lncRNA NEAT1 is a critical modulator of prostate cancerNature Communications2014522
7How COVID-19 induces cytokine storm with high mortalityInflammation and Regeneration2020481
8Attenuated fusogenicity and pathogenicity of SARS-CoV-2 Omicron variantNature2022447
9A regenerative approach to the treatment of multiple sclerosisNature2013436
10Helicobacter pylori CagA targets PAR1/MARK kinase to disrupt epithelial cell polarityNature2007435
11Functional Domains of NEAT1 Architectural lncRNA Induce Paraspeckle Assembly through Phase SeparationMolecular Cell2018429
12Enhanced fusogenicity and pathogenicity of SARS-CoV-2 Delta P681R mutationNature2022428
13Clinical significance of macrophage heterogeneity in human malignant tumorsCancer Science2014425
14Tumor-associated macrophages regulate tumorigenicity and anticancer drug responses of cancer stem/initiating cellsProceedings of the National Academy of Sciences of the United States of America2011409
15Helicobacter pylori CagA interacts with E-cadherin and deregulates the β-catenin signal that promotes intestinal transdifferentiation in gastric epithelial cellsOncogene2007401
16p53 induces formation of NEAT1 lncRNA-containing paraspeckles that modulate replication stress response and chemosensitivityNature Medicine2016372
17The RNA Sensor RIG-I Dually Functions as an Innate Sensor and Direct Antiviral Factor for Hepatitis B VirusImmunity2015353
18Paraspeckles: Where Long Noncoding RNA Meets Phase SeparationTrends in Biochemical Sciences2018315
19Activation of DNA Methyltransferase 1 by EBV Latent Membrane Protein 2A Leads to Promoter Hypermethylation of PTEN Gene in Gastric CarcinomaCancer Research2009314
20CD24 Expression Causes the Acquisition of Multiple Cellular Properties Associated with Tumor Growth and MetastasisCancer Research2005292
21EB virus-encoded RNAs are recognized by RIG-I and activate signaling to induce type I IFNEMBO Journal2006275
22Exosomes Derived from Epstein-Barr Virus-Infected Cells Are Internalized via Caveola-Dependent Endocytosis and Promote Phenotypic Modulation in Target CellsJournal of Virology2013273
23Virological characteristics of the SARS-CoV-2 Omicron BA.2 spikeCell2022273
24Mutant p53 gain-of-function induces epithelial–mesenchymal transition through modulation of the miR-130b–ZEB1 axisOncogene2013270
25Prion-like domains in RNA binding proteins are essential for building subnuclear paraspecklesJournal of Cell Biology2015269
26Epstein-Barr virus (EBV)–encoded small RNA is released from EBV-infected cells and activates signaling from toll-like receptor 3Journal of Experimental Medicine2009265
27Structural, super-resolution microscopy analysis of paraspeckle nuclear body organizationJournal of Cell Biology2016262
28Attenuation of Helicobacter pylori CagA·SHP-2 Signaling by Interaction between CagA and C-terminal Src KinaseJournal of Biological Chemistry2003260
29Constitutive expression of hypoxia-inducible factor-1alpha renders pancreatic cancer cells resistant to apoptosis induced by hypoxia and nutrient deprivationCancer Research2001259
30Helicobacter pylori CagA Induces Ras-independent Morphogenetic Response through SHP-2 Recruitment and ActivationJournal of Biological Chemistry2004250
31Prior Immunization with Severe Acute Respiratory Syndrome (SARS)-Associated Coronavirus (SARS-CoV) Nucleocapsid Protein Causes Severe Pneumonia in Mice Infected with SARS-CoVJournal of Immunology2008236
32Epstein-Barr virus RNA confers resistance to interferon-alpha-induced apoptosis in Burkitt's lymphomaEMBO Journal2002235
33Tumor endothelial cells accelerate tumor metastasisCancer Science2017230
34The lncRNA Neat1 is required for corpus luteum formation and the establishment of pregnancy in a subpopulation of miceDevelopment (Cambridge)2014229
35Gelsolin Inhibits Apoptosis by Blocking Mitochondrial Membrane Potential Loss and Cytochrome c ReleaseJournal of Biological Chemistry2000226
36TDAG8 Is a Proton-sensing and Psychosine-sensitive G-protein-coupled ReceptorJournal of Biological Chemistry2004210
37The interface between innate and acquired immunity: glycolipid antigen presentation by CD1d-expressing dendritic cells to NKT cells induces the differentiation of antigen-specific cytotoxic T lymphocytesInternational Immunology2000208
38Local Radiation Therapy Inhibits Tumor Growth through the Generation of Tumor-Specific CTL: Its Potentiation by Combination with Th1 Cell TherapyCancer Research2010206
39MicroRNA-194 inhibits epithelial to mesenchymal transition of endometrial cancer cells by targeting oncogene BMI-1Molecular Cancer2011206
40A potential function for neuronal exosomes: Sequestering intracerebral amyloid‐β peptideFEBS Letters2015204
41Tumor‐infiltrating IL‐17‐producing γδ T cells support the progression of tumor by promoting angiogenesisEuropean Journal of Immunology2010200
42Editing of Epstein-Barr Virus-encoded BART6 MicroRNAs Controls Their Dicer Targeting and Consequently Affects Viral Latency*Journal of Biological Chemistry2010200
43Interleukin‐6/STAT3 signaling as a promising target to improve the efficacy of cancer immunotherapyCancer Science2017189
44Osteopontin as a Mediator of NKT Cell Function in T Cell-Mediated Liver DiseasesImmunity2004186
45The critical role of Th1-dominant immunity in tumor immunologyCancer Chemotherapy and Pharmacology2000184
46Constitutive aryl hydrocarbon receptor signaling constrains type I interferon–mediated antiviral innate defenseNature Immunology2016182
47Contribution of Tumor Endothelial Cells in Cancer ProgressionInternational Journal of Molecular Sciences2018182
48Natural killer T cells accelerate atherogenesis in miceBlood2004179
49Neat1 is a p53-inducible lincRNA essential for transformation suppressionGenes and Development2017179
50Osteopontin Deficiency Attenuates Atherosclerosis in Female Apolipoprotein E–Deficient MiceArteriosclerosis, Thrombosis, and Vascular Biology2003178