# | Title | Journal | Year | Citations |
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1 | Regulation of endothelium-derived nitric oxide production by the protein kinase Akt | Nature | 1999 | 2,384 |
2 | Mechanisms of neurotransmitter release by amphetamines: A review | Progress in Neurobiology | 2005 | 1,075 |
3 | Ca2+-Induced Apoptosis Through Calcineurin Dephosphorylation of BAD | Science | 1999 | 1,073 |
4 | Hyperpolarization-Activated Cation Currents: From Molecules to Physiological Function | Annual Review of Physiology | 2003 | 1,059 |
5 | PI3K/Akt and apoptosis: size matters | Oncogene | 2003 | 1,051 |
6 | Advanced maturation of human cardiac tissue grown from pluripotent stem cells | Nature | 2018 | 921 |
7 | Structural Basis of Protein Kinase C Isoform Function | Physiological Reviews | 2008 | 735 |
8 | The hippocampal CA2 region is essential for social memory | Nature | 2014 | 729 |
9 | Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis | Nature Chemical Biology | 2016 | 671 |
10 | Requirement of a Macromolecular Signaling Complex for beta Adrenergic Receptor Modulation of the KCNQ1-KCNE1 Potassium Channel | Science | 2002 | 668 |
11 | Effects of Chronic Fluoxetine in Animal Models of Anxiety and Depression | Neuropsychopharmacology | 2004 | 572 |
12 | A Serotonin-Dependent Mechanism Explains the Leptin Regulation of Bone Mass, Appetite, and Energy Expenditure | Cell | 2009 | 565 |
13 | The histochemical localization of cholinesterases in the central nervous system of the rat | Journal of Comparative Neurology | 1954 | 561 |
14 | GTP Cyclohydrolase 1/Tetrahydrobiopterin Counteract Ferroptosis through Lipid Remodeling | ACS Central Science | 2020 | 551 |
15 | Variant of SCN5A Sodium Channel Implicated in Risk of Cardiac Arrhythmia | Science | 2002 | 506 |
16 | Akt/Protein Kinase B Promotes Organ Growth in Transgenic Mice | Molecular and Cellular Biology | 2002 | 481 |
17 | The role of Rab3A in neurotransmitter release | Nature | 1994 | 471 |
18 | FINO2 initiates ferroptosis through GPX4 inactivation and iron oxidation | Nature Chemical Biology | 2018 | 471 |
19 | Molecular mechanism of cAMP modulation of HCN pacemaker channels | Nature | 2001 | 456 |
20 | Postsynaptic induction and presynaptic expression of hippocampal long-term depression | Science | 1994 | 450 |
21 | Transposon-encoded CRISPR–Cas systems direct RNA-guided DNA integration | Nature | 2019 | 420 |
22 | Recent advances in animal models of chronic antidepressant effects: The novelty-induced hypophagia test | Neuroscience and Biobehavioral Reviews | 2005 | 374 |
23 | 5-HT1A Autoreceptor Levels Determine Vulnerability to Stress and Response to Antidepressants | Neuron | 2010 | 373 |
24 | COMPARTMENTATION OFG PROTEIN-COUPLEDSIGNALINGPATHWAYS INCARDIACMYOCYTES | Annual Review of Pharmacology and Toxicology | 2001 | 358 |
25 | Distinctive activation mechanisms and functions for protein kinase Cδ | Biochemical Journal | 2004 | 355 |
26 | Loss of cysteinyl-tRNA synthetase (CARS) induces the transsulfuration pathway and inhibits ferroptosis induced by cystine deprivation | Cell Death and Differentiation | 2016 | 346 |
27 | Regulation of hippocampal transmitter release during development and long-term potentiation | Science | 1995 | 340 |
28 | EFFECT OF MAGNESIUM ION ON THE RESPONSE OF THE RAT UTERUS TO NEUROHYPOPHYSIAL HORMONES AND ANALOGUES1 | Endocrinology | 1960 | 323 |
29 | Mutation of an A-kinase-anchoring protein causes long-QT syndrome | Proceedings of the National Academy of Sciences of the United States of America | 2007 | 309 |
30 | CaMKII tethers to L-type Ca2+ channels, establishing a local and dedicated integrator of Ca2+ signals for facilitation | Journal of Cell Biology | 2005 | 307 |
31 | Essential Roles in Synaptic Plasticity for Synaptogyrin I and Synaptophysin I | Neuron | 1999 | 289 |
32 | Interrelationships Between Automaticity and Conduction in Purkinje Fibers | Circulation Research | 1967 | 276 |
33 | Phosphorylation-Dependent Regulation of Ryanodine Receptors | Journal of Cell Biology | 2001 | 275 |
34 | Behavioral Effects of Chronic Fluoxetine in BALB/cJ Mice Do Not Require Adult Hippocampal Neurogenesis or the Serotonin 1A Receptor | Neuropsychopharmacology | 2008 | 275 |
35 | Targeted gene expression in dopamine and serotonin neurons of the mouse brain | Journal of Neuroscience Methods | 2005 | 265 |
36 | Slow Conduction and Reentry in the Ventricular Conducting System | Circulation Research | 1972 | 261 |
37 | Electrophysiological changes in heart failure and their relationship to arrhythmogenesis | Cardiovascular Research | 2004 | 259 |
38 | Mechanisms of Action of Antiarrhythmic Drugs | Circulation Research | 1973 | 257 |
39 | Dispersion of repolarization in canine ventricle and the electrocardiographic T wave: Tp-e interval does not reflect transmural dispersion | Heart Rhythm | 2007 | 244 |
40 | Folate, Homocysteine, and Arsenic Metabolism in Arsenic-Exposed Individuals in Bangladesh | Environmental Health Perspectives | 2005 | 236 |
41 | Novel cell lines derived from adult human ventricular cardiomyocytes | Journal of Molecular and Cellular Cardiology | 2005 | 236 |
42 | Properties of a nonjunctional current expressed from a rat connexin46 cDNA in Xenopus oocytes. | Journal of General Physiology | 1993 | 228 |
43 | Expression and Function of a Biological Pacemaker in Canine Heart | Circulation | 2003 | 228 |
44 | Regional Differences in Electrophysiological Properties of Epicardium, Midmyocardium, and Endocardium | Circulation | 1996 | 228 |
45 | Mechanisms of Digitalis Toxicity | Circulation | 1973 | 223 |
46 | Slow Conduction and Reentry in the Ventricular Conducting System | Circulation Research | 1972 | 222 |
47 | Caveolar Localization Dictates Physiologic Signaling of β2-Adrenoceptors in Neonatal Cardiac Myocytes | Journal of Biological Chemistry | 2002 | 219 |
48 | Cell-Line Selectivity Improves the Predictive Power of Pharmacogenomic Analyses and Helps Identify NADPH as Biomarker for Ferroptosis Sensitivity | Cell Chemical Biology | 2016 | 217 |
49 | Two components of transient outward current in canine ventricular myocytes. | Circulation Research | 1989 | 214 |
50 | Transient expansion of synaptically connected dendritic spines upon induction of hippocampal long-term potentiation | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 213 |