| # | Title | Journal | Year | Citations |
|---|
| 1 | Oxidative stress, aging, and diseases | Clinical Interventions in Aging | 2018 | 2,366 |
| 2 | COVID-19 Pandemic and Lockdown Measures Impact on Mental Health Among the General Population in Italy | Frontiers in Psychiatry | 2020 | 976 |
| 3 | Essential versus accessory aspects of cell death: recommendations of the NCCD 2015 | Cell Death and Differentiation | 2015 | 811 |
| 4 | Mental Health Outcomes Among Frontline and Second-Line Health Care Workers During the Coronavirus Disease 2019 (COVID-19) Pandemic in Italy | JAMA Network Open | 2020 | 610 |
| 5 | Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women | Nature Medicine | 2018 | 465 |
| 6 | Gut Microbiota and Cancer: From Pathogenesis to Therapy | Cancers | 2019 | 378 |
| 7 | The influence of illness-related variables, personal resources and context-related factors on real-life functioning of people with schizophrenia | World Psychiatry | 2014 | 346 |
| 8 | Design and Control of the MINDWALKER Exoskeleton | IEEE Transactions on Neural Systems and Rehabilitation Engineering | 2015 | 287 |
| 9 | Orexinergic System Dysregulation, Sleep Impairment, and Cognitive Decline in Alzheimer Disease | JAMA Neurology | 2014 | 262 |
| 10 | Immune Activation, Inflammation, and Non-AIDS Co-Morbidities in HIV-Infected Patients under Long-Term ART | Viruses | 2019 | 262 |
| 11 | Patterned control of human locomotion | Journal of Physiology | 2012 | 258 |
| 12 | Metabolically healthy versus metabolically unhealthy obesity | Metabolism: Clinical and Experimental | 2019 | 251 |
| 13 | Health Effects of Phenolic Compounds Found in Extra-Virgin Olive Oil, By-Products, and Leaf of Olea europaea L. | Nutrients | 2019 | 244 |
| 14 | Effects on the incidence of cardiovascular events of the addition of pioglitazone versus sulfonylureas in patients with type 2 diabetes inadequately controlled with metformin (TOSCA.IT): a randomised, multicentre trial | Lancet Diabetes and Endocrinology,the | 2017 | 231 |
| 15 | Impact of Mediterranean diet on metabolic syndrome, cancer and longevity | Oncotarget | 2017 | 231 |
| 16 | A Novel Pharmacologic Inhibitor of the NLRP3 Inflammasome Limits Myocardial Injury After Ischemia–Reperfusion in the Mouse | Journal of Cardiovascular Pharmacology | 2014 | 215 |
| 17 | Interplay Among Psychopathologic Variables, Personal Resources, Context-Related Factors, and Real-life Functioning in Individuals With Schizophrenia | JAMA Psychiatry | 2018 | 214 |
| 18 | Does SARS‐Cov‐2 invade the brain? Translational lessons from animal models | European Journal of Neurology | 2020 | 214 |
| 19 | Klinefelter syndrome (KS): genetics, clinical phenotype and hypogonadism | Journal of Endocrinological Investigation | 2017 | 210 |
| 20 | EGFR heterogeneity and implications for therapeutic intervention in glioblastoma | Neuro-Oncology | 2018 | 210 |
| 21 | A Systematic Review With Meta-Analysis of Dual Bronchodilation With LAMA/LABA for the Treatment of Stable COPD | Chest | 2016 | 206 |
| 22 | Sperm recovery and ICSI outcomes in Klinefelter syndrome: a systematic review and meta-analysis | Human Reproduction Update | 2017 | 200 |
| 23 | Sarcopenia: assessment of disease burden and strategies to improve outcomes | Clinical Interventions in Aging | 2018 | 198 |
| 24 | Genetic deficiency of indoleamine 2,3-dioxygenase promotes gut microbiota-mediated metabolic health | Nature Medicine | 2018 | 193 |
| 25 | Experimental Evidence of the Antitumor, Antimetastatic and Antiangiogenic Activity of Ellagic Acid | Nutrients | 2018 | 178 |
| 26 | Update on the Impact, Diagnosis and Management of Cardiovascular Autonomic Neuropathy in Diabetes: What Is Defined, What Is New, and What Is Unmet | Diabetes and Metabolism Journal | 2019 | 174 |
| 27 | Influence of Mediterranean Diet on Human Gut Microbiota | Nutrients | 2021 | 166 |
| 28 | Role of BRCA Mutations in Cancer Treatment with Poly(ADP-ribose) Polymerase (PARP) Inhibitors | Cancers | 2018 | 154 |
| 29 | Tumor Necrosis Factor and Interleukin-1β Modulate Synaptic Plasticity during Neuroinflammation | Neural Plasticity | 2018 | 149 |
| 30 | Control of reaching movements by muscle synergy combinations | Frontiers in Computational Neuroscience | 2013 | 146 |
| 31 | Fecal and Mucosal Microbiota Profiling in Irritable Bowel Syndrome and Inflammatory Bowel Disease | Frontiers in Microbiology | 2019 | 146 |
| 32 | Dysbiosis of gut microbiota in a selected population of Parkinson's patients | Parkinsonism and Related Disorders | 2019 | 144 |
| 33 | Effects of mutations in Wnt/β-catenin, hedgehog, Notch and PI3K pathways on GSK-3 activity—Diverse effects on cell growth, metabolism and cancer | Biochimica Et Biophysica Acta - Molecular Cell Research | 2016 | 137 |
| 34 | Bowel Ultrasonography in the Management of Crohnʼs Disease. A Review with Recommendations of an International Panel of Experts | Inflammatory Bowel Diseases | 2016 | 137 |
| 35 | Disease Evolution and Response to Rapamycin in Activated Phosphoinositide 3-Kinase δ Syndrome: The European Society for Immunodeficiencies-Activated Phosphoinositide 3-Kinase δ Syndrome Registry | Frontiers in Immunology | 2018 | 137 |
| 36 | The effect of N -acetylcysteine on biofilms: Implications for the treatment of respiratory tract infections | Respiratory Medicine | 2016 | 136 |
| 37 | Metabolomics signature improves the prediction of cardiovascular events in elderly subjects | Atherosclerosis | 2014 | 133 |
| 38 | Optimizing drug delivery in COPD: The role of inhaler devices | Respiratory Medicine | 2017 | 131 |
| 39 | HLA allele frequencies and susceptibility to COVID‐19 in a group of 99 Italian patients | Hla | 2020 | 130 |
| 40 | EFSUMB Recommendations and Clinical Guidelines for Intestinal Ultrasound (GIUS) in Inflammatory Bowel Diseases | Ultraschall in Der Medizin | 2018 | 128 |
| 41 | Hippo Pathway Effectors Control Cardiac Progenitor Cell Fate by Acting as Dynamic Sensors of Substrate Mechanics and Nanostructure | ACS Nano | 2014 | 127 |
| 42 | Role of VEGFs/VEGFR-1 Signaling and Its Inhibition in Modulating Tumor Invasion: Experimental Evidence in Different Metastatic Cancer Models | International Journal of Molecular Sciences | 2020 | 127 |
| 43 | Therapeutic implication of vascular endothelial growth factor receptor-1 (VEGFR-1) targeting in cancer cells and tumor microenvironment by competitive and non-competitive inhibitors | Pharmacological Research | 2018 | 126 |
| 44 | Phase angle as bioelectrical marker to identify elderly patients at risk of sarcopenia | Experimental Gerontology | 2014 | 125 |
| 45 | Sarcopenia and Heart Failure | Nutrients | 2020 | 124 |
| 46 | Benefits of Sexual Activity on Psychological, Relational, and Sexual Health During the COVID-19 Breakout | Journal of Sexual Medicine | 2021 | 120 |
| 47 | The International Society for Sexual Medicine's Process of Care for the Assessment and Management of Testosterone Deficiency in Adult Men | Journal of Sexual Medicine | 2015 | 119 |
| 48 | Biomarkers of conversion to α-synucleinopathy in isolated rapid-eye-movement sleep behaviour disorder | Lancet Neurology, The | 2021 | 116 |
| 49 | High circulating irisin levels are associated with insulin resistance and vascular atherosclerosis in a cohort of nondiabetic adult subjects | Acta Diabetologica | 2014 | 115 |
| 50 | Pirfenidone, nintedanib and N-acetylcysteine for the treatment of idiopathic pulmonary fibrosis: A systematic review and meta-analysis | Pulmonary Pharmacology and Therapeutics | 2016 | 112 |
