| # | Title | Journal | Year | Citations |
|---|
| 1 | Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society | Clinical Infectious Diseases | 2016 | 2,405 |
| 2 | Sphingolipids and their metabolism in physiology and disease | Nature Reviews Molecular Cell Biology | 2018 | 1,197 |
| 3 | The Surviving Sepsis Campaign: results of an international guideline-based performance improvement program targeting severe sepsis | Intensive Care Medicine | 2010 | 1,180 |
| 4 | von Willebrand disease (VWD): evidence‐based diagnosis and management guidelines, the National Heart, Lung, and Blood Institute (NHLBI) Expert Panel report (USA)1 | Haemophilia | 2008 | 815 |
| 5 | LRP/Amyloid β-Peptide Interaction Mediates Differential Brain Efflux of Aβ Isoforms | Neuron | 2004 | 752 |
| 6 | Aerosolized antibiotics and ventilator-associated tracheobronchitis in the intensive care unit* | Critical Care Medicine | 2008 | 729 |
| 7 | Risk of Venous Thromboembolism With the Angiogenesis Inhibitor Bevacizumab in Cancer Patients | JAMA - Journal of the American Medical Association | 2008 | 683 |
| 8 | Organoid Profiling Identifies Common Responders to Chemotherapy in Pancreatic Cancer | Cancer Discovery | 2018 | 676 |
| 9 | Device Selection and Outcomes of Aerosol Therapy: Evidence-Based Guidelines | Chest | 2005 | 659 |
| 10 | A feasibility study evaluating the role of cerebral oximetry in predicting return of spontaneous circulation in cardiac arrest | Resuscitation | 2012 | 631 |
| 11 | Platelets and Thrombolytic Therapy | New England Journal of Medicine | 1990 | 483 |
| 12 | Inhibition of growth factor-induced differentiation of PC12 cells by microinjection of antibody to ras p21 | Nature | 1986 | 428 |
| 13 | Cell type-specific gene expression patterns associated with posttraumatic stress disorder in World Trade Center responders | Translational Psychiatry | 2019 | 383 |
| 14 | Krüppel-like factor 4 (KLF4): What we currently know | Gene | 2017 | 369 |
| 15 | Expression profiles for macrophage alternative activation genes in AD and in mouse models of AD | Journal of Neuroinflammation | 2006 | 358 |
| 16 | Rapamycin and mTOR kinase inhibitors | Journal of Chemical Biology | 2008 | 354 |
| 17 | Aristolochic acid-associated urothelial cancer in Taiwan | Proceedings of the National Academy of Sciences of the United States of America | 2012 | 347 |
| 18 | Executive Summary: Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society | Clinical Infectious Diseases | 2016 | 334 |
| 19 | Cell adaptation to a physiologically relevant ECM mimic with different viscoelastic properties | Biomaterials | 2007 | 331 |
| 20 | Anaphylaxis in America: The prevalence and characteristics of anaphylaxis in the United States | Journal of Allergy and Clinical Immunology | 2014 | 319 |
| 21 | Early-onset and Robust Cerebral Microvascular Accumulation of Amyloid β-Protein in Transgenic Mice Expressing Low Levels of a Vasculotropic Dutch/Iowa Mutant Form of Amyloid β-Protein Precursor | Journal of Biological Chemistry | 2004 | 315 |
| 22 | Increased Hypothalamic Content of Preproneuropeptide Y Messenger Ribonucleic Acid in Genetically Obese Zucker Rats and Its Regulation by Food Deprivation* | Endocrinology | 1990 | 313 |
| 23 | Practice Guidelines for the Treatment of Lyme Disease | Clinical Infectious Diseases | 2000 | 308 |
| 24 | Collagen-platelet interactions: evidence for a direct interaction of collagen with platelet GPIa/IIa and an indirect interaction with platelet GPIIb/IIIa mediated by adhesive proteins | Blood | 1989 | 301 |
| 25 | Direct demonstration of insulin-like growth factor-I-induced nitric oxide production by endothelial cells | Kidney International | 1994 | 292 |
| 26 | Significance of the fractional excretion of urea in the differential diagnosis of acute renal failure | Kidney International | 2002 | 289 |
| 27 | Risk of hypertension and renal dysfunction with an angiogenesis inhibitor sunitinib: Systematic review and meta-analysis | Acta Oncológica | 2009 | 287 |
| 28 | Cellular Entry of Hantaviruses Which Cause Hemorrhagic Fever with Renal Syndrome Is Mediated by β3Integrins | Journal of Virology | 1999 | 279 |
| 29 | Endothelial dysfunction in ischemic acute renal failure: rescue by transplanted endothelial cells | American Journal of Physiology - Renal Physiology | 2002 | 269 |
| 30 | Prevalence and Functional Role of Anti-IgE Autoantibodies in Urticarial Syndromes | Journal of Investigative Dermatology | 1988 | 267 |
| 31 | gC1q-R/p32, a C1q-binding protein, is a receptor for the InlB invasion protein of Listeria monocytogenes | EMBO Journal | 2000 | 265 |
| 32 | Automatic Real Time Detection of Atrial Fibrillation | Annals of Biomedical Engineering | 2009 | 264 |
| 33 | Four Clones of Borrelia burgdorferi Sensu Stricto Cause Invasive Infection in Humans | Infection and Immunity | 1999 | 260 |
| 34 | Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 257 |
| 35 | Persistence of multiple illnesses in World Trade Center rescue and recovery workers: a cohort study | Lancet, The | 2011 | 255 |
| 36 | Severe Babesiosis in Long Island: Review of 34 Cases and Their Complications | Clinical Infectious Diseases | 2001 | 254 |
| 37 | Angiogenic factors stimulate mast-cell migration | Blood | 1995 | 249 |
| 38 | Abolition of in vivo platelet thrombus formation in primates with monoclonal antibodies to the platelet GPIIb/IIIa receptor. Correlation with bleeding time, platelet aggregation, and blockade of GPIIb/IIIa receptors. | Circulation | 1989 | 242 |
| 39 | Assessment of autoimmunity in patients with chronic urticaria | Journal of Allergy and Clinical Immunology | 1997 | 238 |
| 40 | SRF and myocardin regulate LRP-mediated amyloid-β clearance in brain vascular cells | Nature Cell Biology | 2009 | 237 |
| 41 | Trajectories of PTSD risk and resilience in World Trade Center responders: an 8-year prospective cohort study | Psychological Medicine | 2014 | 237 |
| 42 | Tissue distribution of somatostatin receptor subtype messenger ribonucleic acid in the rat. | Endocrinology | 1993 | 235 |
| 43 | Candidiasis and Mechanisms of Antifungal Resistance | Antibiotics | 2020 | 231 |
| 44 | The World Trade Center Disaster and the Health of Workers: Five-Year Assessment of a Unique Medical Screening Program | Environmental Health Perspectives | 2006 | 229 |
| 45 | Doxycycline inhibits neutrophil (PMN)‐type matrix metalloproteinases in human adult periodontitis gingiva | Journal of Clinical Periodontology | 1995 | 224 |
| 46 | Quantitative Deposition of Aerosolized Gentamicin in Cystic Fibrosis | The American Review of Respiratory Disease | 1987 | 222 |
| 47 | Enduring Mental Health Morbidity and Social Function Impairment in World Trade Center Rescue, Recovery, and Cleanup Workers: The Psychological Dimension of an Environmental Health Disaster | Environmental Health Perspectives | 2008 | 215 |
| 48 | Inflammatory Bowel Diseases Phenotype, C. difficile and NOD2 Genotype Are Associated with Shifts in Human Ileum Associated Microbial Composition | PLoS ONE | 2012 | 207 |
| 49 | The Absence of ABCA1 Decreases Soluble ApoE Levels but Does Not Diminish Amyloid Deposition in Two Murine Models of Alzheimer Disease | Journal of Biological Chemistry | 2005 | 203 |
| 50 | Tumor Vesicle—Associated CD147 Modulates the Angiogenic Capability of Endothelial Cells | Neoplasia | 2007 | 203 |
