| # | Title | Journal | Year | Citations |
|---|
| 1 | New insights into the genetic etiology of Alzheimer’s disease and related dementias | Nature Genetics | 2022 | 700 |
| 2 | International consensus statement on the peri‐operative management of anaemia and iron deficiency | Anaesthesia | 2017 | 571 |
| 3 | An update on iron physiology | World Journal of Gastroenterology | 2009 | 277 |
| 4 | Inverse association between habitual polyphenol intake and incidence of cardiovascular events in the PREDIMED study | Nutrition, Metabolism and Cardiovascular Diseases | 2014 | 265 |
| 5 | Transgenic expression and activation of PGC-1α protect dopaminergic neurons in the MPTP mouse model of Parkinson’s disease | Cellular and Molecular Life Sciences | 2012 | 260 |
| 6 | Components of the mediterranean-type food pattern and serum inflammatory markers among patients at high risk for cardiovascular disease | European Journal of Clinical Nutrition | 2008 | 249 |
| 7 | Disorders of iron metabolism. Part II: iron deficiency and iron overload | Journal of Clinical Pathology | 2011 | 229 |
| 8 | A comparative study of the physicochemical properties of iron isomaltoside 1000 (Monofer®), a new intravenous iron preparation and its clinical implications | European Journal of Pharmaceutics and Biopharmaceutics | 2011 | 220 |
| 9 | Receptor–receptor interactions within receptor mosaics. Impact on neuropsychopharmacology | Brain Research Reviews | 2008 | 192 |
| 10 | ‘Fit to fly’: overcoming barriers to preoperative haemoglobin optimization in surgical patients | British Journal of Anaesthesia | 2015 | 181 |
| 11 | Patient Blood Management Bundles to Facilitate Implementation | Transfusion Medicine Reviews | 2017 | 181 |
| 12 | An international consensus statement on the management of postoperative anaemia after major surgical procedures | Anaesthesia | 2018 | 164 |
| 13 | Disorders of iron metabolism. Part 1: molecular basis of iron homoeostasis | Journal of Clinical Pathology | 2011 | 155 |
| 14 | Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores | Nature Communications | 2021 | 140 |
| 15 | Effects of dietary fibre intake on risk factors for cardiovascular disease in subjects at high risk | Journal of Epidemiology and Community Health | 2009 | 138 |
| 16 | Impact of highly active antiretroviral therapy on blood pressure in HIV-infected patients. A prospective study in a cohort of naive patients | HIV Medicine | 2006 | 133 |
| 17 | Essential Role of Patient Blood Management in a Pandemic: A Call for Action | Anesthesia and Analgesia | 2020 | 131 |
| 18 | Associations of the FTO rs9939609 and the MC4R rs17782313 polymorphisms with type 2 diabetes are modulated by diet, being higher when adherence to the Mediterranean diet pattern is low | Cardiovascular Diabetology | 2012 | 129 |
| 19 | Pre-operative anaemia: prevalence, consequences and approaches to management | Blood Transfusion | 2015 | 129 |
| 20 | Adherence to a Mediterranean-type diet and reduced prevalence of clustered cardiovascular risk factors in a cohort of 3204 high-risk patients | European Journal of Cardiovascular Prevention and Rehabilitation | 2008 | 126 |
| 21 | Fibroblast Growth Factor Receptor 1– 5-Hydroxytryptamine 1A Heteroreceptor Complexes and Their Enhancement of Hippocampal Plasticity | Biological Psychiatry | 2012 | 118 |
| 22 | Neuroprotective effect of hydroxytyrosol and hydroxytyrosol acetate in rat brain slices subjected to hypoxia–reoxygenation | Neuroscience Letters | 2008 | 116 |
| 23 | Genome‐wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project | Alzheimer's and Dementia | 2019 | 111 |
| 24 | G Protein–Coupled Receptor Heterodimerization in the Brain | Methods in Enzymology | 2013 | 110 |
| 25 | Perioperative stimulation of erythropoiesis with intravenous iron and erythropoietin reduces transfusion requirements in patients with hip fracture. A prospective observational study | Vox Sanguinis | 2005 | 109 |
| 26 | Efficacy and safety of intravenous iron therapy as an alternative/adjunct to allogeneic blood transfusion | Vox Sanguinis | 2008 | 102 |
| 27 | Perioperative anemia management in colorectal cancer patients: A pragmatic approach | World Journal of Gastroenterology | 2014 | 95 |
| 28 | Characterization of the A2AR–D2R interface: Focus on the role of the C-terminal tail and the transmembrane helices | Biochemical and Biophysical Research Communications | 2010 | 93 |
| 29 | Role of parenteral iron in the management of anaemia in the elderly patient undergoing displaced subcapital hip fracture repair: preliminary data | Archives of Orthopaedic and Trauma Surgery | 2005 | 92 |
| 30 | Inhibition of ferrous-induced lipid peroxidation by pyrimido-pyrimidine derivatives in human liver membranes | Lipids | 1992 | 90 |
| 31 | On the role of P2X7 receptors in dopamine nerve cell degeneration in a rat model of Parkinson’s disease: studies with the P2X7 receptor antagonist A-438079 | Journal of Neural Transmission | 2010 | 89 |
| 32 | Essential requirement of reduced glutathione (GSH) for the anti-oxidant effect of the flavonoid quercetin | Free Radical Research | 2005 | 87 |
| 33 | Low Doses of Insulin-Like Growth Factor I Improve Insulin Resistance, Lipid Metabolism, and Oxidative Damage in Aging Rats | Endocrinology | 2008 | 87 |
| 34 | Oxidative stress in fibroblasts from patients with pseudoxanthoma elasticum: possible role in the pathogenesis of clinical manifestations | Journal of Pathology | 2006 | 85 |
| 35 | Low-fat dairy products and blood pressure: follow-up of 2290 older persons at high cardiovascular risk participating in the PREDIMED study | British Journal of Nutrition | 2009 | 85 |
| 36 | Current misconceptions in diagnosis and management of iron deficiency | Blood Transfusion | 2017 | 83 |
| 37 | Hallucinogenic 5-HT2AR agonists LSD and DOI enhance dopamine D2R protomer recognition and signaling of D2-5-HT2A heteroreceptor complexes | Biochemical and Biophysical Research Communications | 2014 | 78 |
| 38 | Pharmacological approach to diabetic retinopathy | Diabetes/Metabolism Research and Reviews | 2004 | 76 |
| 39 | Patient blood management during the COVID–19 pandemic: a narrative review | Anaesthesia | 2020 | 76 |
| 40 | Effects ofS-adenosyl-L-methionine on hepatic and renal oxidative stress in an experimental model of acute biliary obstruction in rats | Hepatology | 1997 | 74 |
| 41 | Multicenter hospital study on prescribing patterns for prophylaxis and treatment of complications of cirrhosis | European Journal of Clinical Pharmacology | 2002 | 72 |
| 42 | State of the iron: How to diagnose and efficiently treat iron deficiency anemia in inflammatory bowel disease | Journal of Crohn's and Colitis | 2013 | 71 |
| 43 | Exercise, Manual Therapy, and Education with or Without High-Intensity Deep-Water Running for Nonspecific Chronic Low Back Pain | American Journal of Physical Medicine and Rehabilitation | 2011 | 69 |
| 44 | A serine point mutation in the adenosine A2AR C-terminal tail reduces receptor heteromerization and allosteric modulation of the dopamine D2R | Biochemical and Biophysical Research Communications | 2010 | 68 |
| 45 | Fernblock (Polypodium leucotomos Extract): Molecular Mechanisms and Pleiotropic Effects in Light-Related Skin Conditions, Photoaging and Skin Cancers, a Review | International Journal of Molecular Sciences | 2016 | 64 |
| 46 | Statistical and Biological Gene-Lifestyle Interactions of MC4R and FTO with Diet and Physical Activity on Obesity: New Effects on Alcohol Consumption | PLoS ONE | 2012 | 63 |
| 47 | Use of the fluorescent dye 10-N-nonyl acridine orange in quantitative and location assays of cardiolipin: a study on different experimental models | Analytical Biochemistry | 2004 | 62 |
| 48 | Management of Perioperative Iron Deficiency Anemia | Acta Haematologica | 2019 | 62 |
| 49 | Patient dose in radiologically guided interventional vascular procedures: conventional versus digital systems. | Radiology | 1997 | 61 |
| 50 | Dietary Virgin Olive Oil Reduces Oxidative Stress and Cellular Damage in Rat Brain Slices Subjected to Hypoxia–Reoxygenation | Lipids | 2007 | 60 |
