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Top Articles

#TitleJournalYearCitations
1Fusobacterium nucleatum Promotes Chemoresistance to Colorectal Cancer by Modulating AutophagyCell20171,377
2LncRNA GClnc1 Promotes Gastric Carcinogenesis and May Act as a Modular Scaffold of WDR5 and KAT2A Complexes to Specify the Histone Modification PatternCancer Discovery2016339
3Emerging views of mitophagy in immunity and autoimmune diseasesAutophagy2020280
4Inhibiting PD-L1 palmitoylation enhances T-cell immune responses against tumoursNature Biomedical Engineering2019279
5Effect of modulation of PPAR-γ activity on Kupffer cells M1/M2 polarization in the development of non-alcoholic fatty liver diseaseScientific Reports2017194
6HIP1R targets PD-L1 to lysosomal degradation to alter T cell–mediated cytotoxicityNature Chemical Biology2019189
7Enterotoxigenic Bacteroides fragilis Promotes Intestinal Inflammation and Malignancy by Inhibiting Exosome-Packaged miR-149-3pGastroenterology2021130
8Prognosis and personalized treatment prediction in TP53-mutant hepatocellular carcinoma: an in silico strategy towards precision oncologyBriefings in Bioinformatics2021126
9The c-Myc/miR-27b-3p/ATG10 regulatory axis regulates chemoresistance in colorectal cancerTheranostics2020100
10Hepatic cyclooxygenase-2 overexpression induced spontaneous hepatocellular carcinoma formation in miceOncogene201785
11Exosomal miR-208b related with oxaliplatin resistance promotes Treg expansion in colorectal cancerMolecular Therapy202185
12Protecting mitochondria via inhibiting VDAC1 oligomerization alleviates ferroptosis in acetaminophen-induced acute liver injuryCell Biology and Toxicology202272
13Emperipolesis Mediated by CD8 T Cells Is a Characteristic Histopathologic Feature of Autoimmune HepatitisClinical Reviews in Allergy and Immunology201571
14Fecal Microbiota Transplantation for the Treatment of Inflammatory Bowel Disease: An UpdateFrontiers in Pharmacology202070
15TRIM47 is up-regulated in colorectal cancer, promoting ubiquitination and degradation of SMAD4Journal of Experimental and Clinical Cancer Research201969
16<p>Exosome-Delivered c-Met siRNA Could Reverse Chemoresistance to Cisplatin in Gastric Cancer</p>International Journal of Nanomedicine202067
17Proton Pump Inhibitors Do Not Reduce the Risk of Esophageal Adenocarcinoma in Patients with Barrett’s Esophagus: A Systematic Review and Meta-AnalysisPLoS ONE201763
18The immunobiology and clinical features of type 1 autoimmune polyglandular syndrome (APS-1)Autoimmunity Reviews201862
19The risk predictive values of UK‐PBC and GLOBE scoring system in Chinese patients with primary biliary cholangitis: the additional effect of anti‐gp210Alimentary Pharmacology and Therapeutics201761
20Overexpression of NOX4 predicts poor prognosis and promotes tumor progression in human colorectal cancerOncotarget201759
21MOVICS: an R package for multi-omics integration and visualization in cancer subtypingBioinformatics202157
22Low-dose penicillin exposure in early life decreases Th17 and the susceptibility to DSS colitis in mice through gut microbiota modificationScientific Reports201755
23LRG1 promotes proliferation and inhibits apoptosis in colorectal cancer cells via RUNX1 activationPLoS ONE201755
24NPTX2 promotes colorectal cancer growth and liver metastasis by the activation of the canonical Wnt/β-catenin pathway via FZD6Cell Death and Disease201955
25The Natural History and Prognosis of Primary Biliary Cirrhosis with Clinical Features of Autoimmune HepatitisClinical Reviews in Allergy and Immunology201653
26Itraconazole induces apoptosis and cell cycle arrest via inhibiting Hedgehog signaling in gastric cancer cellsJournal of Experimental and Clinical Cancer Research201753
27Differentially Expressed lncRNAs in Gastric Cancer Patients: A Potential Biomarker for Gastric Cancer PrognosisJournal of Cancer201753
28Recurrence‐associated gene signature optimizes recurrence‐free survival prediction of colorectal cancerMolecular Oncology201752
29NOX4-driven ROS formation regulates proliferation and apoptosis of gastric cancer cells through the GLI1 pathwayCellular Signalling201852
30Evaluation of transient elastography in assessing liver fibrosis in patients with autoimmune hepatitisJournal of Gastroenterology and Hepatology (Australia)201750
31RING-Finger Protein 6 Amplification Activates JAK/STAT3 Pathway by Modifying SHP-1 Ubiquitylation and Associates with Poor Outcome in Colorectal CancerClinical Cancer Research201849
32Fecal Fusobacterium nucleatum for the diagnosis of colorectal tumor: A systematic review and meta‐analysisCancer Medicine201948
33Immune response drives outcomes in prostate cancer: implications for immunotherapyMolecular Oncology202148
34Identification of high-risk carotid plaque with MRI-based radiomics and machine learningEuropean Radiology202146
35RAB31 Targeted by MiR-30c-2-3p Regulates the GLI1 Signaling Pathway, Affecting Gastric Cancer Cell Proliferation and ApoptosisFrontiers in Oncology201844
36Personalized CT‐based radiomics nomogram preoperative predicting Ki‐67 expression in gastrointestinal stromal tumors: a multicenter development and validation cohortClinical and Translational Medicine202044
37Turnover of bile acids in liver, serum and caecal content by high-fat diet feeding affects hepatic steatosis in ratsBiochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids201942
38Rational Design of Ratiometric Near-Infrared Aza-BODIPY-Based Fluorescent Probe for in Vivo Imaging of Endogenous Hydrogen PeroxideACS Applied Bio Materials202042
39Loss of Optineurin Drives Cancer Immune Evasion via Palmitoylation-Dependent IFNGR1 Lysosomal Sorting and DegradationCancer Discovery202142
40Epithelial–mesenchymal transition in Crohn's diseaseMucosal Immunology201841
41Comprehensive Analysis of Prognostic Value and Immune Infiltration of Chromobox Family Members in Colorectal CancerFrontiers in Oncology202040
42Bismuth improves efficacy of proton‐pump inhibitor clarithromycin, metronidazole triple Helicobacter pylori therapy despite a high prevalence of antimicrobial resistanceHelicobacter201839
43Down-regulation of long non-coding RNA RP11-708H21.4 is associated with poor prognosis for colorectal cancer and promotes tumorigenesis through regulating AKT/mTOR pathwayOncotarget201739
44Tumor immune microenvironment-based classifications of bladder cancer for enhancing the response rate of immunotherapyMolecular Therapy - Oncolytics202138
45Jumonji domain-containing protein 2B silencing induces DNA damage response via STAT3 pathway in colorectal cancerBritish Journal of Cancer201437
46The roles and functions of Paneth cells in Crohn’s disease: A critical reviewCell Proliferation202137
47Gastric cancer derived exosomes mediate the delivery of circRNA to promote angiogenesis by targeting miR-29a/VEGF axis in endothelial cellsBiochemical and Biophysical Research Communications202137
48The Clinical Significance of GP73 in Immunologically Mediated Chronic Liver Diseases: Experimental Data and Literature ReviewClinical Reviews in Allergy and Immunology201836
49A New Metastatic Lymph Node Classification-based Survival Predicting Model in Patients With Small Bowel Adenocarcinoma: A Derivation and Validation StudyEBioMedicine201836
50TMEFF2 Deregulation Contributes to Gastric Carcinogenesis and Indicates Poor Survival OutcomeClinical Cancer Research201435