| # | Title | Journal | Year | Citations |
|---|
| 1 | The Coagulopathy of Chronic Liver Disease | New England Journal of Medicine | 2011 | 1,171 |
| 2 | Evolving Consensus in Portal Hypertension Report of the Baveno IV Consensus Workshop on methodology of diagnosis and therapy in portal hypertension | Journal of Hepatology | 2005 | 988 |
| 3 | Outcome of patients with obscure gastrointestinal bleeding after capsule endoscopy: Report of 100 consecutive cases | Gastroenterology | 2004 | 892 |
| 4 | The management of ascites in cirrhosis: Report on the consensus conference of the International Ascites Club | Hepatology | 2003 | 744 |
| 5 | Upper digestive bleeding in cirrhosis. Post-therapeutic outcome and prognostic indicators | Hepatology | 2003 | 732 |
| 6 | The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Belgian Diabetes Registry | Human Molecular Genetics | 1996 | 686 |
| 7 | Risk of severe liver disease in nonalcoholic fatty liver disease with normal aminotransferase levels: A role for insulin resistance and diabetes | Hepatology | 2008 | 600 |
| 8 | APOE and Alzheimer disease: a major gene with semi-dominant inheritance | Molecular Psychiatry | 2011 | 529 |
| 9 | Updating Consensus in Portal Hypertension: Report of the Baveno III Consensus Workshop on definitions, methodology and therapeutic strategies in portal hypertension | Journal of Hepatology | 2000 | 527 |
| 10 | Diagnosis, prevention and treatment of hepatorenal syndrome in cirrhosis | Postgraduate Medical Journal | 2008 | 504 |
| 11 | Transjugular Intrahepatic Portosystemic Shunt for Refractory Ascites: A Meta-analysis of Individual Patient Data | Gastroenterology | 2007 | 494 |
| 12 | Pathogenesis of antiphospholipid syndrome: understanding the antibodies | Nature Reviews Rheumatology | 2011 | 482 |
| 13 | ANA screening: an old test with new recommendations | Annals of the Rheumatic Diseases | 2010 | 425 |
| 14 | Expression of the potent inflammatory cytokines, granulocyte-macrophage-colony-stimulating factor and interleukin-6 and interleukin-8, in bronchial epithelial cells of patients with asthma | Journal of Allergy and Clinical Immunology | 1992 | 377 |
| 15 | NATURAL HISTORY OF PORTAL HYPERTENSION IN PATIENTS WITH CIRRHOSIS | Clinics in Liver Disease | 2001 | 332 |
| 16 | Survival and Disease Complications in Thalassemia Major | Annals of the New York Academy of Sciences | 1998 | 312 |
| 17 | Role of the MyD88 transduction signaling pathway in endothelial activation by antiphospholipid antibodies | Blood | 2003 | 290 |
| 18 | Iron in fatty liver and in the metabolic syndrome: A promising therapeutic target | Journal of Hepatology | 2011 | 279 |
| 19 | Ecallantide for the Treatment of Acute Attacks in Hereditary Angioedema | New England Journal of Medicine | 2010 | 266 |
| 20 | Frequency of monosomy X in women with primary biliary cirrhosis | Lancet, The | 2004 | 252 |
| 21 | Natural history of portal hypertensive gastropathy in patients with liver cirrhosis | Gastroenterology | 2000 | 248 |
| 22 | MELD score is better than Child–Pugh score in predicting 3-month survival of patients undergoing transjugular intrahepatic portosystemic shunt | Journal of Hepatology | 2002 | 248 |
| 23 | HFE Genotype, Parenchymal Iron Accumulation, and Liver Fibrosis in Patients With Nonalcoholic Fatty Liver Disease | Gastroenterology | 2010 | 246 |
| 24 | Clinical Pharmacokinetics of Atypical Antipsychotics | Clinical Pharmacokinetics | 2007 | 217 |
| 25 | Short sleep duration and cardiometabolic risk: from pathophysiology to clinical evidence | Nature Reviews Cardiology | 2019 | 211 |
| 26 | C1-inhibitor deficiency and angioedema: molecular mechanisms and clinical progress | Trends in Molecular Medicine | 2009 | 207 |
| 27 | The systemic inflammatory response syndrome in cirrhotic patients: Relationship with their in-hospital outcome | Journal of Hepatology | 2009 | 205 |
| 28 | Bradykinin and the pathophysiology of angioedema | International Immunopharmacology | 2003 | 197 |
| 29 | Incidence and risk factors for non-alcoholic steatohepatitis: prospective study of 5408 women enrolled in Italian tamoxifen chemoprevention trial | BMJ: British Medical Journal | 2005 | 196 |
| 30 | Diastolic dysfunction is associated with poor survival in patients with cirrhosis with transjugular intrahepatic portosystemic shunt | Gut | 2007 | 195 |
| 31 | Cellular and biochemical characteristics of bronchoalveolar lavage fluid in symptomatic nonallergic asthma | Journal of Allergy and Clinical Immunology | 1991 | 194 |
| 32 | Early Impairment of Gut Function and Gut Flora Supporting a Role for Alteration of Gastrointestinal Mucosa in Human Immunodeficiency Virus Pathogenesis | Journal of Clinical Microbiology | 2008 | 191 |
| 33 | Optimal management of β thalassaemia intermedia | British Journal of Haematology | 2011 | 187 |
| 34 | Angioedema Associated With Angiotensin-Converting Enzyme Inhibitor Use | Archives of Internal Medicine | 2004 | 184 |
| 35 | Toll-like receptor and antiphospholipid mediated thrombosis: in vivo studies | Annals of the Rheumatic Diseases | 2007 | 184 |
| 36 | Insulin VNTR allele-specific effect in type 1 diabetes depends on identity of untransmitted paternal allele | Nature Genetics | 1997 | 183 |
| 37 | cDNA Cloning and Functional Characterization of the Mouse Ca2+-gated K+ Channel, mIK1 | Journal of Biological Chemistry | 1998 | 183 |
| 38 | Molecular bases of defective signal transduction in the platelet P2Y12 receptor of a patient with congenital bleeding | Proceedings of the National Academy of Sciences of the United States of America | 2003 | 183 |
| 39 | Hereditary angiodema: a current state-of-the-art review, VII: Canadian Hungarian 2007 International Consensus Algorithm for the Diagnosis, Therapy, and Management of Hereditary Angioedema | Annals of Allergy, Asthma and Immunology | 2008 | 181 |
| 40 | Chronic unexplained hypertransaminasemia may be caused by occult celiac disease | Hepatology | 1999 | 179 |
| 41 | Risk factors for a first thrombotic event in antiphospholipid antibody carriers: a prospective multicentre follow-up study | Annals of the Rheumatic Diseases | 2011 | 178 |
| 42 | Specific prebiotics modulate gut microbiota and immune activation in HAART-naive HIV-infected adults: results of the “COPA” pilot randomized trial | Mucosal Immunology | 2011 | 177 |
| 43 | Risk Factors in Venous Thromboembolism | Thrombosis and Haemostasis | 2001 | 176 |
| 44 | Aminopeptidase P in individuals with a history of angio-oedema on ACE inhibitors | Lancet, The | 2002 | 173 |
| 45 | Activity Assays and Immunoassays for Plasma Renin and Prorenin: Information Provided and Precautions Necessary for Accurate Measurement | Clinical Chemistry | 2009 | 172 |
| 46 | Angioedema without urticaria: a large clinical survey | Cmaj | 2006 | 170 |
| 47 | Local bradykinin generation in hereditary angioedema☆☆☆★ | Journal of Allergy and Clinical Immunology | 1999 | 168 |
| 48 | How I treat transfusional iron overload | Blood | 2012 | 168 |
| 49 | An update on iron chelation therapy | Blood Transfusion | 2012 | 164 |
| 50 | Increased Expression and Activity of the Transcription Factor FOXO1 in Nonalcoholic Steatohepatitis | Diabetes | 2008 | 163 |
