# | Title | Journal | Year | Citations |
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1 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
2 | Role of Macrophage Targeting in the Antitumor Activity of Trabectedin | Cancer Cell | 2013 | 721 |
3 | Paclitaxel is incorporated by mesenchymal stromal cells and released in exosomes that inhibit in vitro tumor growth: A new approach for drug delivery | Journal of Controlled Release | 2014 | 697 |
4 | iPSC-derived neurons from GBA1-associated Parkinson’s disease patients show autophagic defects and impaired calcium homeostasis | Nature Communications | 2014 | 436 |
5 | The trans-ancestral genomic architecture of glycemic traits | Nature Genetics | 2021 | 341 |
6 | Exome-wide Rare Variant Analysis Identifies TUBA4A Mutations Associated with Familial ALS | Neuron | 2014 | 308 |
7 | Tivantinib for second-line treatment of MET-high, advanced hepatocellular carcinoma (METIV-HCC): a final analysis of a phase 3, randomised, placebo-controlled study | Lancet Oncology, The | 2018 | 285 |
8 | Insulin resistance in obesity: an overview of fundamental alterations | Eating and Weight Disorders | 2018 | 218 |
9 | Folate, folic acid and 5-methyltetrahydrofolate are not the same thing | Xenobiotica | 2014 | 200 |
10 | Membrane domains and the "lipid raft" concept | Current Medicinal Chemistry | 2013 | 187 |
11 | Active endocannabinoids are secreted on extracellular membrane vesicles | EMBO Reports | 2015 | 182 |
12 | European Academy of Neurology/Peripheral Nerve Society guideline on diagnosis and treatment of chronic inflammatory demyelinating polyradiculoneuropathy: Report of a joint Task Force—Second revision | Journal of the Peripheral Nervous System | 2021 | 176 |
13 | New Oral Anticoagulants: Comparative Pharmacology with Vitamin K Antagonists | Clinical Pharmacokinetics | 2013 | 172 |
14 | Pharmacotherapy for Neuropathic Pain: A Review | Pain and Therapy | 2017 | 166 |
15 | Phase behavior and critical activated dynamics of limited-valence DNA nanostars | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 156 |
16 | European Academy of Neurology/Peripheral Nerve Society guideline on diagnosis and treatment of chronic inflammatory demyelinating polyradiculoneuropathy: Report of a joint Task Force—Second revision | European Journal of Neurology | 2021 | 153 |
17 | ATP-Gated Ionotropic P2X7 Receptor Controls Follicular T Helper Cell Numbers in Peyer’s Patches to Promote Host-Microbiota Mutualism | Immunity | 2014 | 152 |
18 | Single Cell T Cell Receptor Sequencing: Techniques and Future Challenges | Frontiers in Immunology | 2018 | 143 |
19 | Exercise Training Induces Mitochondrial Biogenesis and Glucose Uptake in Subcutaneous Adipose Tissue Through eNOS-Dependent Mechanisms | Diabetes | 2014 | 139 |
20 | Guillain-Barré syndrome and COVID-19: an observational multicentre study from two Italian hotspot regions | Journal of Neurology, Neurosurgery and Psychiatry | 2021 | 135 |
21 | Adipocyte cannabinoid receptor CB1 regulates energy homeostasis and alternatively activated macrophages | Journal of Clinical Investigation | 2017 | 128 |
22 | SNAP-25, a Known Presynaptic Protein with Emerging Postsynaptic Functions | Frontiers in Synaptic Neuroscience | 2016 | 122 |
23 | Infections after T‐replete haploidentical transplantation and high‐dose cyclophosphamide as graft‐versus‐host disease prophylaxis | Transplant Infectious Disease | 2015 | 118 |
24 | Applications of Lysozyme, an Innate Immune Defense Factor, as an Alternative Antibiotic | Antibiotics | 2021 | 118 |
25 | Unjamming overcomes kinetic and proliferation arrest in terminally differentiated cells and promotes collective motility of carcinoma | Nature Materials | 2019 | 117 |
26 | Phosphorylation of neuronal Lysine‐Specific Demethylase 1LSD1/KDM1A impairs transcriptional repression by regulating interaction with CoREST and histone deacetylases HDAC1/2 | Journal of Neurochemistry | 2014 | 112 |
27 | GM1 Ganglioside: Past Studies and Future Potential | Molecular Neurobiology | 2016 | 112 |
28 | Ellagitannins from Rubus Berries for the Control of Gastric Inflammation: In Vitro and In Vivo Studies | PLoS ONE | 2013 | 109 |
29 | Vitamin D Status and SARS-CoV-2 Infection and COVID-19 Clinical Outcomes | Frontiers in Public Health | 2021 | 108 |
30 | Branched‐chain amino acids differently modulate catabolic and anabolic states in mammals: a pharmacological point of view | British Journal of Pharmacology | 2017 | 107 |
31 | Developmental vulnerability of synapses and circuits associated with neuropsychiatric disorders | Journal of Neurochemistry | 2013 | 106 |
32 | Lipid membrane domains in the brain | Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids | 2015 | 106 |
33 | Neuromelanin organelles are specialized autolysosomes that accumulate undegraded proteins and lipids in aging human brain and are likely involved in Parkinson’s disease | Npj Parkinson's Disease | 2018 | 101 |
34 | Exercise training boosts eNOS-dependent mitochondrial biogenesis in mouse heart: role in adaptation of glucose metabolism | American Journal of Physiology - Endocrinology and Metabolism | 2014 | 96 |
35 | The light and the dark sides of Interleukin-10 in immune-mediated diseases and cancer. | Cytokine and Growth Factor Reviews | 2016 | 95 |
36 | The glucose and lipid metabolism reprogramming is grade-dependent in clear cell renal cell carcinoma primary cultures and is targetable to modulate cell viability and proliferation | Oncotarget | 2017 | 95 |
37 | Sphingolipids: Key Regulators of Apoptosis and Pivotal Players in Cancer Drug Resistance | International Journal of Molecular Sciences | 2014 | 94 |
38 | Human Leukocyte Antigen Complex and Other Immunogenetic and Clinical Factors Influence Susceptibility or Protection to SARS-CoV-2 Infection and Severity of the Disease Course. The Sardinian Experience | Frontiers in Immunology | 2020 | 92 |
39 | Human umbilical endothelial cells (HUVECs) have a sex: characterisation of the phenotype of male and female cells | Biology of Sex Differences | 2014 | 91 |
40 | Mesenchymal stem cells: potential for therapy and treatment of chronic non-healing skin wounds | Organogenesis | 2015 | 91 |
41 | GM1 Ganglioside Is A Key Factor in Maintaining the Mammalian Neuronal Functions Avoiding Neurodegeneration | International Journal of Molecular Sciences | 2020 | 91 |
42 | Lipid rafts and neurodegeneration: structural and functional roles in physiologic aging and neurodegenerative diseases | Journal of Lipid Research | 2020 | 88 |
43 | miR-128-3p Is a Novel Regulator of Vascular Smooth Muscle Cell Phenotypic Switch and Vascular Diseases | Circulation Research | 2020 | 88 |
44 | Extracellular vesicle-packaged miRNA release after short-term exposure to particulate matter is associated with increased coagulation | Particle and Fibre Toxicology | 2017 | 85 |
45 | LRRK2 kinase activity regulates synaptic vesicle trafficking and neurotransmitter release through modulation of LRRK2 macro-molecular complex | Frontiers in Molecular Neuroscience | 2014 | 82 |
46 | A carnosine analog mitigates metabolic disorders of obesity by reducing carbonyl stress | Journal of Clinical Investigation | 2018 | 80 |
47 | Membrane Domains and the “Lipid Raft” Concept | Current Medicinal Chemistry | 2012 | 80 |
48 | Intestinal IFN-γ–producing type 1 regulatory T cells coexpress CCR5 and programmed cell death protein 1 and downregulate IL-10 in the inflamed guts of patients with inflammatory bowel disease | Journal of Allergy and Clinical Immunology | 2018 | 79 |
49 | Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer’s disease-like pathology in human cerebral organoids | Molecular Psychiatry | 2021 | 79 |
50 | Clinical and molecular characterization of Rubinstein‐Taybi syndrome patients carrying distinct novel mutations of the EP300 gene | Clinical Genetics | 2015 | 75 |