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Top Articles

#TitleJournalYearCitations
1The genome of the domesticated apple (Malus × domestica Borkh.)Nature Genetics20101,891
2Protein carbonyl groups as biomarkers of oxidative stressClinica Chimica Acta20031,888
3Biomarkers of Oxidative Damage in Human DiseaseClinical Chemistry20061,395
4Protein carbonylation in human diseasesTrends in Molecular Medicine2003813
5Protein carbonylation, cellular dysfunction, and disease progressionJournal of Cellular and Molecular Medicine2006691
6Genetic structure and domestication history of the grapeProceedings of the National Academy of Sciences of the United States of America2011684
7Extinction debt of high-mountain plants under twenty-first-century climate changeNature Climate Change2012582
8Protein S-glutathionylation: a regulatory device from bacteria to humansTrends in Biochemical Sciences2009557
9S-glutathionylation in protein redox regulationFree Radical Biology and Medicine2007422
10Proteins as biomarkers of oxidative/nitrosative stress in diseases: The contribution of redox proteomicsMass Spectrometry Reviews2005392
11The actin cytoskeleton response to oxidants: from small heat shock protein phosphorylation to changes in the redox state of actin itselfFree Radical Biology and Medicine2001353
12Oxidative stress and human diseases: Origin, link, measurement, mechanisms, and biomarkersCritical Reviews in Clinical Laboratory Sciences2009348
13Molecular Mechanisms and Potential Clinical Significance ofS-GlutathionylationAntioxidants and Redox Signaling2008275
14Nitrite and Nitrate Measurement by Griess Reagent in Human Plasma: Evaluation of Interferences and StandardizationMethods in Enzymology2008272
15S-Glutathionylation: from redox regulation of protein functions to human diseasesJournal of Cellular and Molecular Medicine2004265
16Intervention strategies to inhibit protein carbonylation by lipoxidation-derived reactive carbonylsMedicinal Research Reviews2007256
17Blood Glutathione Disulfide: In Vivo Factor or in Vitro Artifact?Clinical Chemistry2002227
18The Impact of the Absence of Aliphatic Glucosinolates on Insect Herbivory in ArabidopsisPLoS ONE2008223
19Specific hypomethylation of DNA is induced by heavy metals in white clover and industrial hempPhysiologia Plantarum2004221
20Amphibians in a human-dominated landscape: the community structure is related to habitat features and isolationBiological Conservation2004207
21Growth factors, CD34 positive cells, and fibrin network analysis in concentrated growth factors fractionMicroscopy Research and Technique2011205
22Inflammatory and alternatively activated human macrophages attract vessel-associated stem cells, relying on separate HMGB1- and MMP-9-dependent pathwaysJournal of Leukocyte Biology2009194
23Evidence of epigenetic changes affecting the chromatin state of the retinoic acid receptor β2 promoter in breast cancer cellsOncogene2000188
24Evidence of a secondary grapevine domestication centre detected by SSR analysisTheoretical and Applied Genetics2003178
25Reversible S-glutathionylation of Cys374 regulates actin filament formation by inducing structural changes in the actin moleculeFree Radical Biology and Medicine2003178
26In vivo experiments for the evaluation of genotoxic and cytotoxic effects of Triclosan in Zebra mussel hemocytesAquatic Toxicology2009175
27Impact of tire debris on in vitro and in vivo systemsParticle and Fibre Toxicology2005161
28The Wnt/β-catenin pathway regulates Gli-mediated Myf5expression during somitogenesisDevelopment (Cambridge)2006159
29Engineered cobalt oxide nanoparticles readily enter cellsToxicology Letters2009149
30Actin carbonylation: from a simple marker of protein oxidation to relevant signs of severe functional impairmentFree Radical Biology and Medicine2001148
31Mesenchymal Stromal Cells Primed with Paclitaxel Provide a New Approach for Cancer TherapyPLoS ONE2011146
32Two and three-color fluorescence flow cytometric analysis of immunoidentified viable bacteriaCytometry2000141
33An improved HPLC measurement for GSH and GSSG in human bloodFree Radical Biology and Medicine2003140
34Autophagy precedes apoptosis during the remodeling of silkworm larval midgutApoptosis: an International Journal on Programmed Cell Death2012140
35Analysis of the petunia MADS-box transcription factor familyMolecular Genetics and Genomics2003132
36Molecular phylogeny of the Caryophyllaceae (Caryophyllales) inferred from chloroplast matK and nuclear rDNA ITS sequencesAmerican Journal of Botany2006131
37S-Nitrosation versus S-Glutathionylation of Protein Sulfhydryl Groups by S-NitrosoglutathioneAntioxidants and Redox Signaling2005127
38Methionine oxidation as a major cause of the functional impairment of oxidized actinFree Radical Biology and Medicine2002126
39Impaired Adult Neurogenesis Associated with Short-Term Memory Defects in NF-κB p50-Deficient MiceJournal of Neuroscience2008126
40Oxidized Forms of Glutathione in Peripheral Blood as Biomarkers of Oxidative StressClinical Chemistry2006125
41Chronic effects induced by ibuprofen on the freshwater bivalve Dreissena polymorphaEcotoxicology and Environmental Safety2011123
42Clathrin-dependent and independent endocytic pathways in tobacco protoplasts revealed by labelling with charged nanogoldJournal of Experimental Botany2008121
43Detection of S-nitrosothiols in biological fluids: A comparison among the most widely applied methodologiesJournal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences2007120
44Bone morphogenic protein antagonist Drm/gremlin is a novel proangiogenic factorBlood2007118
45Multi-biomarker approach for the evaluation of the cyto-genotoxicity of paracetamol on the zebra mussel (Dreissena polymorpha)Chemosphere2010118
46Nitric oxide and S-nitrosothiols in human bloodClinica Chimica Acta2003117
47Vaccine antigen production in transgenic plants: strategies, gene constructs and perspectivesVaccine2003117
48Structure of the genetic diversity in black poplar (Populus nigra L.) populations across European river systems: Consequences for conservation and restorationForest Ecology and Management2008116
49The timing and the mode of evolution of wild grapes (Vitis)Molecular Phylogenetics and Evolution2012114
50Preparation of immobilized pH gradients spanning 2-6 pH units with two-chamber mixers: Evaluation of two experimental approachesElectrophoresis1984113