| # | Title | Journal | Year | Citations |
|---|
| 1 | Immediate or delayed dissection of regional nodes in patients with melanoma of the trunk: a randomised trial | Lancet, The | 1998 | 625 |
| 2 | Nadroparin for the prevention of thromboembolic events in ambulatory patients with metastatic or locally advanced solid cancer receiving chemotherapy: a randomised, placebo-controlled, double-blind study | Lancet Oncology, The | 2009 | 538 |
| 3 | Prognostic Significance of Vascular Endothelial Growth Factor Protein in Node-Negative Breast Carcinoma | Journal of the National Cancer Institute | 1997 | 466 |
| 4 | Intratumoral microvessel density and L53 protein: Correlation with metastasis in head-and-neck squamous-cell carcinoma | International Journal of Cancer | 1993 | 302 |
| 5 | Interferon Adjuvant to Radical Nephrectomy in Robson Stages II and III Renal Cell Carcinoma: A Multicentric Randomized Study | Journal of Clinical Oncology | 2001 | 253 |
| 6 | In-stent restenosis in small coronary arteries | Journal of the American College of Cardiology | 2002 | 244 |
| 7 | Fifteen-year results of a randomized phase III trial of fenretinide to prevent second breast cancer | Annals of Oncology | 2006 | 187 |
| 8 | HYAFF 11-Based Autologous Dermal and Epidermal Grafts in the Treatment of Noninfected Diabetic Plantar and Dorsal Foot Ulcers: A prospective, multicenter, controlled, randomized clinical trial | Diabetes Care | 2003 | 180 |
| 9 | Response to Cyclophosphamide, Methotrexate, and Fluorouracil in Lymph Node–Positive Breast Cancer According to HER2 Overexpression and Other Tumor Biologic Variables | Journal of Clinical Oncology | 2001 | 147 |
| 10 | Pattern and quality of care of cancer pain management. Results from the Cancer Pain Outcome Research Study Group | British Journal of Cancer | 2009 | 141 |
| 11 | Maternal and fetal amino acid concentrations in normal pregnancies and in pregnancies with gestational diabetes mellitus | American Journal of Obstetrics and Gynecology | 2005 | 140 |
| 12 | Urinary Markers of Bone Turnover in Healthy Children and Adolescents: Age-Related Changes and Effect of Puberty | Calcified Tissue International | 1998 | 136 |
| 13 | Incidence of thrombotic complications in patients with haematological malignancies with central venous catheters: a prospective multicentre study | British Journal of Haematology | 2005 | 134 |
| 14 | Prognostic and predictive value of tumour angiogenesis in ovarian carcinomas | British Journal of Haematology | 1996 | 115 |
| 15 | High rates of hepatocellular carcinoma in cirrhotic patients with high liver cell proliferative activity | Hepatology | 2001 | 106 |
| 16 | Prognostic value of intratumoral microvessel density, a measure of tumor angiogenesis, in node-negative breast carcinoma ? results of a multiparametric study | Breast Cancer Research and Treatment | 1995 | 102 |
| 17 | HER2 Overexpression and Doxorubicin in Adjuvant Chemotherapy for Resectable Breast Cancer | Journal of Clinical Oncology | 2003 | 99 |
| 18 | Drug-Eluting Stent Restenosis | Journal of the American College of Cardiology | 2006 | 92 |
| 19 | Chemotherapy-associated thromboembolic risk in cancer outpatients and effect of nadroparin thromboprophylaxis: results of a retrospective analysis of the PROTECHT study | Journal of Translational Medicine | 2011 | 90 |
| 20 | First-trimester Down's syndrome screening using nuchal translucency: a prospective study in patients undergoing chorionic villus sampling | Ultrasound in Obstetrics and Gynecology | 1995 | 81 |
| 21 | Cell kinetics in human breast cancer: Comparison between the prognostic value of the cytofluorimetric S-phase fraction and that of the antibodies to Ki-67 and PCNA antigens detected by immunocytochemistry | International Journal of Cancer | 1994 | 75 |
| 22 | Randomized trial of fenretinide (4‐HPR) to prevent recurrences, new localizations and carcinomas in patients operated on for oral leukoplakia: Long‐term results | International Journal of Cancer | 2005 | 73 |
| 23 | EURAP: An International Registry of Antiepileptic Drugs and Pregnancy | Epilepsia | 2004 | 70 |
| 24 | Feasibility of Different Capillaroscopic Measures for Identifying Nailfold Microvascular Alterations | Seminars in Arthritis and Rheumatism | 2009 | 66 |
| 25 | 67-kDa laminin-receptor expression adds prognostic information to intra-tumoral microvessel density in node-negative breast cancer | International Journal of Cancer | 1995 | 65 |
| 26 | Ticlopidine versus aspirin after myocardial infarction (stami) trial | Journal of the American College of Cardiology | 2001 | 61 |
| 27 | Soy isoflavones and melatonin for the relief of climacteric symptoms: a multicenter, double-blind, randomized study | Maturitas | 2004 | 58 |
| 28 | Birthmarks and Transient Skin Lesions in Newborns and Their Relationship to Maternal Factors: A Preliminary Report from Northern Italy | Dermatology | 2007 | 58 |
| 29 | Epithelial cell polarity and tumorigenesis: new perspectives for cancer detection and treatment | Acta Pharmacologica Sinica | 2011 | 58 |
| 30 | A microcomputer program for probit analysis of interleukin-2 (IL-2) titration data | Journal of Immunological Methods | 1986 | 57 |
| 31 | Is axillary lymph node dissection necessary in elderly patients with breast carcinoma who have a clinically uninvolved axilla? | Cancer | 2003 | 56 |
| 32 | Clinically Overt Venous Thromboembolism after Urologic Cancer Surgery: Results from the @RISTOS Study | European Urology | 2007 | 55 |
| 33 | Menopause hormone replacement therapy and cancer risk: an Italian record linkage investigation | Annals of Oncology | 2008 | 55 |
| 34 | A methodology to identify consensus classes from clustering algorithms applied to immunohistochemical data from breast cancer patients | Computers in Biology and Medicine | 2010 | 55 |
| 35 | The Food Composition Database for an Italian Food Frequency Questionnaire | Journal of Food Composition and Analysis | 1996 | 54 |
| 36 | Lymphadenectomy in gastric cancer: prognostic role and therapeutic implications | European Journal of Surgical Oncology | 2002 | 53 |
| 37 | Ogenetic development of the 5α-reductase in the rat brain: cerebral cortex, hypothalamus, purified myelin and isolated oligodendrocytes | Developmental Brain Research | 1988 | 51 |
| 38 | Bone histomorphometric reference values in 88 normal Italian subjects | Bone and Mineral | 1990 | 42 |
| 39 | Angiogenesis Sustains Tumor Dormancy in Patients with Breast Cancer Treated with Adjuvant Chemotherapy | Breast Cancer Research and Treatment | 2001 | 39 |
| 40 | EQUAL-quant: An International External Quality Assessment Scheme for Real-Time PCR | Clinical Chemistry | 2006 | 39 |
| 41 | Allogeneic bone marrow transplantation versus chemotherapy in high-risk childhood acute lymphoblastic leukaemia in first remission | British Journal of Haematology | 1997 | 37 |
| 42 | Exploratory tools for disease mapping in geographical epidemiology | Statistics in Medicine | 1995 | 34 |
| 43 | Chemoprevention Trial of Contralateral Breast Cancer with Fenretinide. Rationale, Design, Methodology, Organization, Data Management, Statistics and Accrual | Tumori | 1997 | 32 |
| 44 | EVALUATION OF LONG-TERM SURVIVAL: USE OF DIAGNOSTICS AND ROBUST ESTIMATORS WITH COX'S PROPORTIONAL HAZARDS MODEL | Tumori | 1996 | 31 |
| 45 | A multiparametric study on the prognostic value of epidermal growth factor receptor in operable breast carcinoma | Breast Cancer Research and Treatment | 1994 | 30 |
| 46 | An immunohistochemically positive E-cadherin status is not always predictive for a good prognosis in human breast cancer | British Journal of Cancer | 2010 | 30 |
| 47 | Surgical resection plus tamoxifen as treatment of breast cancer in elderly patients: a retrospective study | European Journal of Cancer | 1993 | 29 |
| 48 | Acute Limb Ischemia in Elderly Patients: Can Iloprost be Useful as an Adjuvant to Surgery? Results from the ILAILL Study | European Journal of Vascular and Endovascular Surgery | 2007 | 28 |
| 49 | Flexible Modelling in Survival Analysis. Structuring Biological Complexity from the Information Provided by Tumor Markers | International Journal of Biological Markers | 1998 | 25 |
| 50 | Technical variability of bone histomorphometric measurements | Bone and Mineral | 1990 | 24 |
