| # | Title | Journal | Year | Citations |
|---|
| 1 | Rapid Whole-Genome Sequencing for Genetic Disease Diagnosis in Neonatal Intensive Care Units | Science Translational Medicine | 2012 | 534 |
| 2 | STS-ACC TVT Registry of Transcatheter Aortic Valve Replacement | Journal of the American College of Cardiology | 2020 | 511 |
| 3 | Relationship of Obesity with Osteoporosis | Journal of Clinical Endocrinology and Metabolism | 2007 | 494 |
| 4 | Valve Academic Research Consortium 3: Updated Endpoint Definitions for Aortic Valve Clinical Research | Journal of the American College of Cardiology | 2021 | 416 |
| 5 | Correlation of Obesity and Osteoporosis: Effect of Fat Mass on the Determination of Osteoporosis | Journal of Bone and Mineral Research | 2008 | 408 |
| 6 | Mouse model of Parkinsonism: a comparison between subacute MPTP and chronic MPTP/probenecid treatment | Neuroscience | 2001 | 288 |
| 7 | American Society of Hematology 2018 guidelines for management of venous thromboembolism: diagnosis of venous thromboembolism | Blood Advances | 2018 | 271 |
| 8 | MCP-induced protein 1 deubiquitinates TRAF proteins and negatively regulates JNK and NF-κB signaling | Journal of Experimental Medicine | 2010 | 260 |
| 9 | Comparative evaluation of implant designs: influence of diameter, length, and taper on strains in the alveolar crest | Clinical Oral Implants Research | 2005 | 259 |
| 10 | RNA-binding proteins in immune regulation: a focus on CCCH zinc finger proteins | Nature Reviews Immunology | 2017 | 258 |
| 11 | IgE allergy diagnostics and other relevant tests in allergy, a World Allergy Organization position paper | World Allergy Organization Journal | 2020 | 245 |
| 12 | Cleavage of roquin and regnase-1 by the paracaspase MALT1 releases their cooperatively repressed targets to promote TH17 differentiation | Nature Immunology | 2014 | 238 |
| 13 | Modulation of D2R-NR2B Interactions in Response to Cocaine | Neuron | 2006 | 235 |
| 14 | Regulation of mitogen-activated protein kinases by glutamate receptors | Journal of Neurochemistry | 2007 | 230 |
| 15 | The Scaffold Protein Homer1b/c Links Metabotropic Glutamate Receptor 5 to Extracellular Signal-Regulated Protein Kinase Cascades in Neurons | Journal of Neuroscience | 2005 | 218 |
| 16 | Genome-wide Copy-Number-Variation Study Identified a Susceptibility Gene, UGT2B17, for Osteoporosis | American Journal of Human Genetics | 2008 | 209 |
| 17 | Connections between the human gut microbiome and gestational diabetes mellitus | GigaScience | 2017 | 204 |
| 18 | Benefits of aspirin and beta-blockade after myocardial infarction in patients with chronic kidney disease | American Heart Journal | 2002 | 195 |
| 19 | Lysosomal malfunction accompanies alpha-synuclein aggregation in a progressive mouse model of Parkinson’s disease | Brain Research | 2002 | 195 |
| 20 | Genome-wide association scans identified CTNNBL1 as a novel gene for obesity | Human Molecular Genetics | 2008 | 168 |
| 21 | FGF23 is a novel regulator of intracellular calcium and cardiac contractility in addition to cardiac hypertrophy | American Journal of Physiology - Endocrinology and Metabolism | 2013 | 162 |
| 22 | Global and Regional Burden of Infective Endocarditis, 1990–2010: A Systematic Review of the Literature | Global Heart | 2014 | 162 |
| 23 | The ERK Pathway: Molecular Mechanisms and Treatment of Depression | Molecular Neurobiology | 2019 | 159 |
| 24 | Brain-derived neurotrophic factor expression is increased in the rat amygdala, piriform cortex and hypothalamus following repeated amphetamine administration | Brain Research | 2002 | 152 |
| 25 | Clinical Pharmacogenetics Implementation Consortium Guideline for Cytochrome P450 (CYP)2D6 Genotype and Atomoxetine Therapy | Clinical Pharmacology and Therapeutics | 2019 | 152 |
| 26 | Voltage-Gated Ion Channels in Cancer Cell Proliferation | Cancers | 2015 | 149 |
| 27 | Phenotypic integration of neurocranium and brain | Journal of Experimental Zoology Part B: Molecular and Developmental Evolution | 2006 | 143 |
| 28 | Meta-Analysis of Effect of Dipeptidyl Peptidase-4 Inhibitors on Cardiovascular Risk in Type 2 Diabetes Mellitus | American Journal of Cardiology | 2012 | 141 |
| 29 | FGF23 directly impairs endothelium-dependent vasorelaxation by increasing superoxide levels and reducing nitric oxide bioavailability | American Journal of Physiology - Endocrinology and Metabolism | 2014 | 138 |
| 30 | Extended Swimming Exercise Reduces Inflammatory and Peripheral Neuropathic Pain in Rodents | Journal of Pain | 2007 | 137 |
| 31 | Role of anthocyanin-enriched purple-fleshed sweet potato p40 in colorectal cancer prevention | Molecular Nutrition and Food Research | 2013 | 137 |
| 32 | Genome Partitioning of Genetic Variation for Height from 11,214 Sibling Pairs | American Journal of Human Genetics | 2007 | 135 |
| 33 | Polarizing Macrophages In Vitro | Methods in Molecular Biology | 2018 | 135 |
| 34 | American Association of Clinical Endocrinology Clinical Practice Guideline: The Use of Advanced Technology in the Management of Persons With Diabetes Mellitus | Endocrine Practice | 2021 | 135 |
| 35 | MiR-9 promotes microglial activation by targeting MCPIP1 | Nature Communications | 2014 | 133 |
| 36 | Recreational marijuana use and acute ischemic stroke: A population-based analysis of hospitalized patients in the United States | Journal of the Neurological Sciences | 2016 | 131 |
| 37 | β-aminoisobutyric Acid, l-BAIBA, Is a Muscle-Derived Osteocyte Survival Factor | Cell Reports | 2018 | 131 |
| 38 | Resveratrol inhibits estrogen-induced breast carcinogenesis through induction of NRF2-mediated protective pathways | Carcinogenesis | 2014 | 128 |
| 39 | Phosphorylation of AMPA Receptors: Mechanisms and Synaptic Plasticity | Molecular Neurobiology | 2005 | 125 |
| 40 | A Novel Ca2+-Independent Signaling Pathway to Extracellular Signal-Regulated Protein Kinase by Coactivation of NMDA Receptors and Metabotropic Glutamate Receptor 5 in Neurons | Journal of Neuroscience | 2004 | 122 |
| 41 | Ontogeny of Hepatic Drug Transporters as Quantified by LC‐MS/MS Proteomics | Clinical Pharmacology and Therapeutics | 2016 | 122 |
| 42 | Analyses and Comparison of Accuracy of Different Genotype Imputation Methods | PLoS ONE | 2008 | 117 |
| 43 | The relationship in neonates between clinically measured head circumference and brain volume estimated from head CT-scans | Early Human Development | 1999 | 116 |
| 44 | 3-Year Outcomes of Transcatheter Mitral Valve Repair in Patients With Heart Failure | Journal of the American College of Cardiology | 2021 | 113 |
| 45 | Impact of radiotherapy dose on dentition breakdown in head and neck cancer patients | Practical Radiation Oncology | 2011 | 111 |
| 46 | Ten Years’ Experience with the CYP2D6 Activity Score: A Perspective on Future Investigations to Improve Clinical Predictions for Precision Therapeutics | Journal of Personalized Medicine | 2018 | 110 |
| 47 | PharmVar GeneFocus: CYP2B6 | Clinical Pharmacology and Therapeutics | 2021 | 108 |
| 48 | Stability of surface NMDA receptors controls synaptic and behavioral adaptations to amphetamine | Nature Neuroscience | 2009 | 106 |
| 49 | The Evolution of PharmVar | Clinical Pharmacology and Therapeutics | 2019 | 106 |
| 50 | TRIM59 Promotes the Proliferation and Migration of Non-Small Cell Lung Cancer Cells by Upregulating Cell Cycle Related Proteins | PLoS ONE | 2015 | 105 |
