| # | Title | Journal | Year | Citations |
|---|
| 1 | Cyclosporine | New England Journal of Medicine | 1989 | 1,523 |
| 2 | The underappreciated role of muscle in health and disease | American Journal of Clinical Nutrition | 2006 | 1,081 |
| 3 | A genomic storm in critically injured humans | Journal of Experimental Medicine | 2011 | 1,040 |
| 4 | Clinical Practice Guidelines From the AABB | JAMA - Journal of the American Medical Association | 2016 | 871 |
| 5 | A high proportion of leucine is required for optimal stimulation of the rate of muscle protein synthesis by essential amino acids in the elderly | American Journal of Physiology - Endocrinology and Metabolism | 2006 | 734 |
| 6 | Stabilization of Snail by NF-κB Is Required for Inflammation-Induced Cell Migration and Invasion | Cancer Cell | 2009 | 719 |
| 7 | Reversal of Catabolism by Beta-Blockade after Severe Burns | New England Journal of Medicine | 2001 | 626 |
| 8 | Influence of cyclosporine pharmacokinetics, trough concentrations, and AUC monitoring on outcome after kidney transplantation | Clinical Pharmacology and Therapeutics | 1993 | 449 |
| 9 | REDUCTION OF THE OCCURRENCE OF ACUTE CELLULAR REJECTION AMONG RENAL ALLOGRAFT RECIPIENTS TREATED WITH BASILIXIMAB, A CHIMERIC ANTI-INTERLEUKIN-2-RECEPTOR MONOCLONAL ANTIBODY1,2 | Transplantation | 1999 | 447 |
| 10 | Testosterone administration to older men improves muscle function: molecular and physiological mechanisms | American Journal of Physiology - Endocrinology and Metabolism | 2002 | 445 |
| 11 | A Comparison of Conservative Versus Early Excision | Annals of Surgery | 1989 | 430 |
| 12 | Aging is associated with diminished accretion of muscle proteins after the ingestion of a small bolus of essential amino acids | American Journal of Clinical Nutrition | 2005 | 428 |
| 13 | Hypertrophic scarring: the greatest unmet challenge after burn injury | Lancet, The | 2016 | 415 |
| 14 | Testosterone administration in severe burns ameliorates muscle catabolism | Critical Care Medicine | 2001 | 412 |
| 15 | Timing of amino acid-carbohydrate ingestion alters anabolic response of muscle to resistance exercise | American Journal of Physiology - Endocrinology and Metabolism | 2001 | 411 |
| 16 | Human Muscle Protein Synthesis is Modulated by Extracellular, Not Intramuscular Amino Acid Availability: A Dose‐Response Study | Journal of Physiology | 2003 | 409 |
| 17 | Amino acid ingestion improves muscle protein synthesis in the young and elderly | American Journal of Physiology - Endocrinology and Metabolism | 2004 | 395 |
| 18 | Akt interacts directly with Smad3 to regulate the sensitivity to TGF-β-induced apoptosis | Nature Cell Biology | 2004 | 370 |
| 19 | Rapid Report | Journal of Physiology | 2001 | 355 |
| 20 | Essential amino acids and muscle protein recovery from resistance exercise | American Journal of Physiology - Endocrinology and Metabolism | 2002 | 346 |
| 21 | Age at acquisition of Helicobacter pylori infection: a follow-up study from infancy to adulthood | Lancet, The | 2002 | 341 |
| 22 | Exogenous amino acids stimulate net muscle protein synthesis in the elderly. | Journal of Clinical Investigation | 1998 | 340 |
| 23 | FOXO Proteins Regulate Tumor Necrosis Factor-related Apoptosis Inducing Ligand Expression | Journal of Biological Chemistry | 2002 | 329 |
| 24 | Effect of Delirium and Other Major Complications on Outcomes After Elective Surgery in Older Adults | JAMA Surgery | 2015 | 328 |
| 25 | Insulin resistance of muscle protein metabolism in aging | FASEB Journal | 2006 | 312 |
| 26 | Increasing use of gonadotropin-releasing hormone agonists for the treatment of localized prostate carcinoma | Cancer | 2005 | 309 |
| 27 | Determinants of Skeletal Muscle Catabolism After Severe Burn | Annals of Surgery | 2000 | 301 |
| 28 | Mortality Determinants in Massive Pediatric Burns | Annals of Surgery | 1997 | 301 |
| 29 | Bile duct injury after laparoscopic cholecystectomy | Surgical Endoscopy and Other Interventional Techniques | 1998 | 286 |
| 30 | PROTEIN ANDAMINOACIDMETABOLISMDURING ANDAFTEREXERCISE AND THEEFFECTS OFNUTRITION | Annual Review of Nutrition | 2000 | 282 |
| 31 | The leading causes of death after burn injury in a single pediatric burn center | Critical Care | 2009 | 274 |
| 32 | Surgeon Burnout: A Systematic Review | Journal of the American College of Surgeons | 2016 | 273 |
| 33 | Terephthalic acid: A dosimeter for the detection of hydroxyl radicals in vitro | Life Sciences | 1994 | 262 |
| 34 | The Surgically Induced Stress Response | Journal of Parenteral and Enteral Nutrition | 2013 | 262 |
| 35 | Circulating Catecholamines and Sympathetic Activity after Head Injury | Neurosurgery | 1981 | 260 |
| 36 | The side effect profile of sirolimus: A phase I study in quiescent cyclosporine-prednisone-treated renal transplant patients | Kidney International | 1996 | 241 |
| 37 | Anabolic Effects of Oxandrolone After Severe Burn | Annals of Surgery | 2001 | 240 |
| 38 | The Safety and Effect of Topically Applied Recombinant Basic Fibroblast Growth Factor on the Healing of Chronic Pressure Sores | Annals of Surgery | 1992 | 234 |
| 39 | Effect of amino acid supplementation on muscle mass, strength and physical function in elderly | Clinical Nutrition | 2008 | 229 |
| 40 | The metabolic stress response to burn trauma: current understanding and therapies | Lancet, The | 2016 | 224 |
| 41 | Progressive Loss of Pancreatic Function in Chronic Pancreatitis Is Delayed by Main Pancreatic Duct Decompression A Longitudinal Prospective Analysis of the Modified Puestow Procedure | Annals of Surgery | 1993 | 218 |
| 42 | Effects of Burn Wound Excision on Bacterial Colonization and Invasion | Plastic and Reconstructive Surgery | 2003 | 215 |
| 43 | The role of the gut in the development of sepsis in acute pancreatitis | Journal of Surgical Research | 1991 | 213 |
| 44 | A Submaximal Dose of Insulin Promotes Net Skeletal Muscle Protein Synthesis in Patients With Severe Burns | Annals of Surgery | 1999 | 210 |
| 45 | Response rates and pathologic complete response by breast cancer molecular subtype following neoadjuvant chemotherapy | Breast Cancer Research and Treatment | 2018 | 207 |
| 46 | Protein and amino acids for athletes | Journal of Sports Sciences | 2004 | 205 |
| 47 | Novel Expression Patterns of PI3K/Akt/mTOR Signaling Pathway Components in Colorectal Cancer | Journal of the American College of Surgeons | 2010 | 203 |
| 48 | Establishment and characterization of a human carcinoid in nude mice and effect of various agents on tumor growth | Gastroenterology | 1991 | 200 |
| 49 | The Therapeutic Potential of Cystathionine β-Synthetase/Hydrogen Sulfide Inhibition in Cancer | Antioxidants and Redox Signaling | 2015 | 198 |
| 50 | Current Treatment of Severely Burned Patients | Annals of Surgery | 1996 | 195 |
