| # | Title | Journal | Year | Citations |
|---|
| 1 | Sex differences in the functional organization of the brain for language | Nature | 1995 | 1,332 |
| 2 | Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4 | Science | 2014 | 745 |
| 3 | Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID | Science | 1994 | 645 |
| 4 | The Disease Spectrum ofHelicobacter Pylori: The Immunopathogenesis of Gastroduodenal Ulcer and Gastric Cancer | Annual Review of Microbiology | 2000 | 518 |
| 5 | Corticotropin-releasing activity of monokines | Science | 1985 | 505 |
| 6 | Prevalence of Various Respiratory Viruses in the Middle Ear during Acute Otitis Media | New England Journal of Medicine | 1999 | 480 |
| 7 | A recurrent mutation in the tyrosine kinase domain of fibroblast growth factor receptor 3 causes hypochondroplasia | Nature Genetics | 1995 | 443 |
| 8 | 1,25-dihydroxyvitamin D3 prevents the in vivo induction of murine experimental autoimmune encephalomyelitis. | Journal of Clinical Investigation | 1991 | 436 |
| 9 | Persistence of Dyslexia: The Connecticut Longitudinal Study at Adolescence | Pediatrics | 1999 | 382 |
| 10 | Viral Upper Respiratory Tract Infection and Otitis Media Complication in Young Children | Clinical Infectious Diseases | 2008 | 356 |
| 11 | Corticotropin releasing factor induction of leukocyte-derived immunoreactive ACTH and endorphins | Nature | 1986 | 352 |
| 12 | Linkage of an important gene locus for tuberous sclerosis to a chromosome 16 marker for polycystic kidney disease | Nature Genetics | 1992 | 334 |
| 13 | Otitis media | Nature Reviews Disease Primers | 2016 | 332 |
| 14 | Role of prothrombin complex concentrates in reversing warfarin anticoagulation: A review of the literature | American Journal of Hematology | 2008 | 327 |
| 15 | Correlates of Insulin Injection Omission | Diabetes Care | 2010 | 327 |
| 16 | MILK ALLERGY | Pediatrics | 1963 | 302 |
| 17 | Neonatal Candidiasis: Epidemiology, Risk Factors, and Clinical Judgment | Pediatrics | 2010 | 294 |
| 18 | Expression of interleukin 8 and CD54 by human gastric epithelium after Helicobacter pylori infection in vitro | Gastroenterology | 1995 | 288 |
| 19 | Host resistance factors in human milk | Journal of Pediatrics | 1973 | 283 |
| 20 | Immunologic factors in human milk during the first year of lactation | Journal of Pediatrics | 1982 | 274 |
| 21 | Identification and Functional Characterization of tRNA-derived RNA Fragments (tRFs) in Respiratory Syncytial Virus Infection | Molecular Therapy | 2013 | 251 |
| 22 | Cell-Specific Expression of RANTES, MCP-1, and MIP-1α by Lower Airway Epithelial Cells and Eosinophils Infected with Respiratory Syncytial Virus | Journal of Virology | 1998 | 246 |
| 23 | International workshop on immune tolerance induction: consensus recommendations | Haemophilia | 2007 | 228 |
| 24 | Respiratory Syncytial Virus–Induced Activation of Nuclear Factor–κB in the Lung Involves Alveolar Macrophages and Toll‐Like Receptor 4–Dependent Pathways | Journal of Infectious Diseases | 2002 | 225 |
| 25 | Effect of an Enhanced Medical Home on Serious Illness and Cost of Care Among High-Risk Children With Chronic Illness | JAMA - Journal of the American Medical Association | 2014 | 217 |
| 26 | Proteinuria and hematuria in schoolchildren: Epidemiology and early natural history | Journal of Pediatrics | 1976 | 208 |
| 27 | Macrophage Inflammatory Protein–1α (Not T Helper Type 2 Cytokines) Is Associated with Severe Forms of Respiratory Syncytial Virus Bronchiolitis | Journal of Infectious Diseases | 2001 | 206 |
| 28 | The Somatomedin C Binding Protein: Evidence for a Heterologous Subunit Structure* | Journal of Clinical Endocrinology and Metabolism | 1980 | 204 |
| 29 | CBFA1 Mutation Analysis and Functional Correlation with Phenotypic Variability in Cleidocranial Dysplasia | Human Molecular Genetics | 1999 | 204 |
| 30 | Breastfeeding: maintaining an irreplaceable immunological resource | Nature Reviews Immunology | 2004 | 201 |
| 31 | Review article: the role of inflammation in the pathogenesis of gastric cancer | Alimentary Pharmacology and Therapeutics | 1999 | 196 |
| 32 | Modulation of the Gastrointestinal Tract of Infants by Human Milk. Interfaces and Interactions. An Evolutionary Perspective | Journal of Nutrition | 2000 | 193 |
| 33 | Antibodies to silicone elastomers and reactions to ventriculoperitoneal shunts | Lancet, The | 1992 | 192 |
| 34 | REDUCED INTER- AND INTRASUBJECT VARIABILITY IN CYCLOSPORINE PHARMACOKINETICS IN RENAL TRANSPLANT RECIPIENTS TREATED WITH A MICROEMULSION FORMULATION IN CONJUNCTION WITH FASTING, LOW-FAT MEALS, OR HIGH-FAT MEALS1,2 | Transplantation | 1995 | 191 |
| 35 | Multiple effects of silymarin on the hepatitis C virus lifecycle | Hepatology | 2010 | 191 |
| 36 | The Effect of Class II Major Histocompatibility Complex Expression on Adherence of Helicobacter pylori and Induction of Apoptosis in Gastric Epithelial Cells: A Mechanism for T Helper Cell Type 1–mediated Damage | Journal of Experimental Medicine | 1998 | 190 |
| 37 | Cytokines in Human Milk | Journal of Pediatrics | 2010 | 188 |
| 38 | TGF-β2 Suppresses Macrophage Cytokine Production and Mucosal Inflammatory Responses in the Developing Intestine | Gastroenterology | 2011 | 186 |
| 39 | Impaired Clearance of Herpes Simplex Virus Type 1 From Mice Lacking CD1d or NKT Cells Expressing the Semivariant Vα14-Jα281 TCR | Journal of Immunology | 2003 | 185 |
| 40 | Effect of viral respiratory tract infection on outcome of acute otitis media | Journal of Pediatrics | 1992 | 184 |
| 41 | Group A Rotaviruses Produce Extrahepatic Biliary Obstruction in Orally Inoculated Newborn Mice | Pediatric Research | 1993 | 184 |
| 42 | Trends in Otitis Media–Related Health Care Use in the United States, 2001-2011 | JAMA Pediatrics | 2014 | 184 |
| 43 | Position Effects Due to Chromosome Breakpoints that Map ∼900 Kb Upstream and ∼1.3 Mb Downstream of SOX9 in Two Patients with Campomelic Dysplasia | American Journal of Human Genetics | 2005 | 178 |
| 44 | Androgen-stimulated pubertal growth: the effects of testosterone and dihydrotestosterone on growth hormone and insulin-like growth factor-I in the treatment of short stature and delayed puberty. | Journal of Clinical Endocrinology and Metabolism | 1993 | 176 |
| 45 | Effect of l -carnitine treatment for valproate-induced hepatotoxicity | Neurology | 2001 | 174 |
| 46 | Prevention and control of sexually transmitted infections among adolescents: the importance of a socio-ecological perspective—a commentary | Public Health | 2005 | 171 |
| 47 | Differential Response of Dendritic Cells to Human Metapneumovirus and Respiratory Syncytial Virus | American Journal of Respiratory Cell and Molecular Biology | 2006 | 171 |
| 48 | Mutations in PIEZO2 Cause Gordon Syndrome, Marden-Walker Syndrome, and Distal Arthrogryposis Type 5 | American Journal of Human Genetics | 2014 | 171 |
| 49 | Respiratory Syncytial Virus Induces Oxidative Stress by Modulating Antioxidant Enzymes | American Journal of Respiratory Cell and Molecular Biology | 2009 | 170 |
| 50 | Cytokines in Breast Milk from Allergic and Nonallergic Mothers | Pediatric Research | 2000 | 170 |
