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Top Articles

#TitleJournalYearCitations
1Magnetic Resonance Imaging More Accurately Classifies Steatosis and Fibrosis in Patients With Nonalcoholic Fatty Liver Disease Than Transient ElastographyGastroenterology2016628
2TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccinesNature2008551
3Sarcopenia, intramuscular fat deposition, and visceral adiposity independently predict the outcomes of hepatocellular carcinomaJournal of Hepatology2015538
4De novo mutations in the autophagy gene WDR45 cause static encephalopathy of childhood with neurodegeneration in adulthoodNature Genetics2013396
5Noninvasive assessment of liver fibrosis by measurement of stiffness in patients with nonalcoholic fatty liver disease (NAFLD)Digestive and Liver Disease2008361
6Upregulating mutations in the TERT promoter commonly occur in adult malignant gliomas and are strongly associated with total 1p19q lossActa Neuropathologica2013315
7Diagnostic Accuracy of Ultrasound Scanning for Prenatal Microcephaly in the context of Zika Virus Infection: A Systematic Review and Meta-analysisScientific Reports2017285
8IRF8 Is a Critical Transcription Factor for Transforming Microglia into a Reactive PhenotypeCell Reports2012249
9Clinical practice guidelines for the management of biliary tract cancers 2015: the 2nd English editionJournal of Hepato-Biliary-Pancreatic Sciences2015205
10Enhanced Self-Renewal Capability in Hepatic Stem/Progenitor Cells Drives Cancer InitiationGastroenterology2007190
11A combination of TERT promoter mutation and MGMT methylation status predicts clinically relevant subgroups of newly diagnosed glioblastomasActa Neuropathologica Communications2016189
12De Novo Mutations in GNAO1, Encoding a Gαo Subunit of Heterotrimeric G Proteins, Cause Epileptic EncephalopathyAmerican Journal of Human Genetics2013187
13The Blumgart Preoperative Staging System for Hilar Cholangiocarcinoma: Analysis of Resectability and Outcomes in 380 PatientsJournal of the American College of Surgeons2012184
14Recurrent mutations of CD79B and MYD88 are the hallmark of primary central nervous system lymphomasNeuropathology and Applied Neurobiology2016172
15Live imaging of apoptosis in a novel transgenic mouse highlights its role in neural tube closureJournal of Cell Biology2011168
16Efficacy and safety of monotherapy with the novel sodium/glucose cotransporter-2 inhibitor tofogliflozin in Japanese patients with type 2 diabetes mellitus: a combined Phase 2 and 3 randomized, placebo-controlled, double-blind, parallel-group comparative studyCardiovascular Diabetology2014168
17Relationship between urinary sodium excretion and pioglitazone‐induced edemaJournal of Diabetes Investigation2010162
18Strength Deficits Identified With Concentric Action of the Hip Extensors and Eccentric Action of the Hamstrings Predispose to Hamstring Injury in Elite SprintersJournal of Orthopaedic and Sports Physical Therapy2008157
19NLRP4 Negatively Regulates Autophagic Processes through an Association with Beclin1Journal of Immunology2011153
20Lessons from Mouse Models of High-Fat Diet-Induced NAFLDInternational Journal of Molecular Sciences2013150
21MLL2 and KDM6A mutations in patients with Kabuki syndromeAmerican Journal of Medical Genetics, Part A2013148
22Identification of KLHL41 Mutations Implicates BTB-Kelch-Mediated Ubiquitination as an Alternate Pathway to Myofibrillar Disruption in Nemaline MyopathyAmerican Journal of Human Genetics2013147
23Effectiveness of a Breastfeeding Self-efficacy Intervention: Do Hospital Practices Make a Difference?Maternal and Child Health Journal2014142
24Early onset epileptic encephalopathy caused by de novo SCN8A mutationsEpilepsia2014142
25Smaller amygdala is associated with anxiety in patients with panic disorderPsychiatry and Clinical Neurosciences2009141
26Exosomal miRNAs from Peritoneum Lavage Fluid as Potential Prognostic Biomarkers of Peritoneal Metastasis in Gastric CancerPLoS ONE2015141
27Mutations in POLR3A and POLR3B Encoding RNA Polymerase III Subunits Cause an Autosomal-Recessive Hypomyelinating LeukoencephalopathyAmerican Journal of Human Genetics2011137
28Risk factors for delayed bleeding after endoscopic submucosal dissection for gastric neoplasmSurgical Endoscopy and Other Interventional Techniques2011133
29Dominant mutations in ORAI1 cause tubular aggregate myopathy with hypocalcemia via constitutive activation of store-operated Ca2+ channelsHuman Molecular Genetics2015132
30Sporadic Nonampullary Duodenal Adenoma in the Natural History of Duodenal Cancer: A Study of Follow-up SurveillanceAmerican Journal of Gastroenterology2011130
31Serum Ferritin Is Associated With Visceral Fat Area and Subcutaneous Fat AreaDiabetes Care2005126
32Isolation of Mouse Pancreatic Ductal Progenitor Cells Expressing CD133 and c-Met by Flow Cytometric Cell SortingGastroenterology2007126
33Preoperative Serum Carcinoembryonic Antigen Level as a Predictive Factor of Recurrence After Curative Resection of Colorectal CancerAnnals of Surgical Oncology2008125
34Clinical factors predictive of spontaneous remission or relapse in cases of autoimmune pancreatitisGastrointestinal Endoscopy2007124
35Tbx3 controls the fate of hepatic progenitor cells in liver development by suppressingp19ARFexpressionDevelopment (Cambridge)2008122
36Regulatory role of heme oxygenase 1 in inflammation of rheumatoid arthritisArthritis and Rheumatism2006120
37Long-term outcomes of endoscopic submucosal dissection for undifferentiated-type early gastric cancerEndoscopy2012120
38Revisiting TP53 Mutations and Immunohistochemistry—A Comparative Study in 157 Diffuse GliomasBrain Pathology2015120
39Stem Cell Therapy for Cerebral Ischemia: From Basic Science to Clinical ApplicationsJournal of Cerebral Blood Flow and Metabolism2012114
40Robust and Highly-Efficient Differentiation of Functional Monocytic Cells from Human Pluripotent Stem Cells under Serum- and Feeder Cell-Free ConditionsPLoS ONE2013114
41Role of three-dimensional imaging in operative planning for hilar cholangiocarcinomaSurgery2007113
42DNA methylation and gene expression dynamics during spermatogonial stem cell differentiation in the early postnatal mouse testisBMC Genomics2015112
43Clinical practice guidelines for the management of biliary tract cancers 2019: The 3rd English editionJournal of Hepato-Biliary-Pancreatic Sciences2021112
44The RNA-binding protein FUS/TLS is a common aggregate-interacting protein in polyglutamine diseasesNeuroscience Research2010110
45Tumor-targeting Salmonella typhimurium A1-R in combination with doxorubicin eradicate soft tissue sarcoma in a patient-derived orthotopic xenograft (PDOX) modelOncotarget2016109
46Collapsin Response Mediator Proteins Regulate Neuronal Development and Plasticity by Switching Their Phosphorylation StatusMolecular Neurobiology2012105
47Diagnostic utility of whole exome sequencing in patients showing cerebellar and/or vermis atrophy in childhoodNeurogenetics2013104
48A multicenter randomized trial indicates initial prednisolone treatment for childhood nephrotic syndrome for two months is not inferior to six-month treatmentKidney International2015104
49Therapeutic strategy for signet ring cell carcinoma of the stomachBritish Journal of Surgery2004103
50Self‐sterilization using silicone catheters coated with Ag and TiO2 nanocomposite thin filmJournal of Biomedical Materials Research - Part B Applied Biomaterials2008103