| # | Title | Journal | Year | Citations |
|---|
| 1 | Evidence that Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths | Nutrients | 2020 | 1,391 |
| 2 | EULAR recommendations for cardiovascular disease risk management in patients with rheumatoid arthritis and other forms of inflammatory joint disorders: 2015/2016 update | Annals of the Rheumatic Diseases | 2017 | 918 |
| 3 | Current state of knowledge on aetiology, diagnosis, management, and therapy of peripartum cardiomyopathy: a position statement from the Heart Failure Association of the European Society of Cardiology Working Group on peripartum cardiomyopathy | European Journal of Heart Failure | 2010 | 787 |
| 4 | Brentuximab vedotin with chemotherapy for CD30-positive peripheral T-cell lymphoma (ECHELON-2): a global, double-blind, randomised, phase 3 trial | Lancet, The | 2019 | 517 |
| 5 | Heterozygous STAT1 gain-of-function mutations underlie an unexpectedly broad clinical phenotype | Blood | 2016 | 465 |
| 6 | Vitamin D supplementation guidelines | Journal of Steroid Biochemistry and Molecular Biology | 2018 | 454 |
| 7 | Comparative genomics reveals high biological diversity and specific adaptations in the industrially and medically important fungal genus Aspergillus | Genome Biology | 2017 | 417 |
| 8 | 2016 update of the EULAR recommendations for the management of early arthritis | Annals of the Rheumatic Diseases | 2017 | 393 |
| 9 | The international EAACI/GA²LEN/EuroGuiDerm/APAAACI guideline for the definition, classification, diagnosis, and management of urticaria | Allergy: European Journal of Allergy and Clinical Immunology | 2022 | 392 |
| 10 | Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy | Acta Neuropathologica | 2016 | 380 |
| 11 | Novel bis-Tetrahydrofuranylurethane-Containing Nonpeptidic Protease Inhibitor (PI) UIC-94017 (TMC114) with Potent Activity against Multi-PI-Resistant Human Immunodeficiency Virus In Vitro | Antimicrobial Agents and Chemotherapy | 2003 | 355 |
| 12 | The PREDICT study uncovers three clinical courses of acutely decompensated cirrhosis that have distinct pathophysiology | Journal of Hepatology | 2020 | 282 |
| 13 | The Impact of Obesity on the Cardiovascular System | Journal of Diabetes Research | 2018 | 274 |
| 14 | 2018 update of the EULAR recommendations for the management of hand osteoarthritis | Annals of the Rheumatic Diseases | 2019 | 273 |
| 15 | The Hill equation and the origin of quantitative pharmacology | Archive for History of Exact Sciences | 2012 | 264 |
| 16 | The phase 3 DUO trial: duvelisib vs ofatumumab in relapsed and refractory CLL/SLL | Blood | 2018 | 261 |
| 17 | Organ dysfunction, injury and failure in acute heart failure: from pathophysiology to diagnosis and management. A review on behalf of the Acute Heart Failure Committee of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC) | European Journal of Heart Failure | 2017 | 252 |
| 18 | The Role of Indoleamine-2,3-Dioxygenase in Cancer Development, Diagnostics, and Therapy | Frontiers in Immunology | 2018 | 245 |
| 19 | Tissue Determinants of Human NK Cell Development, Function, and Residence | Cell | 2020 | 242 |
| 20 | ASCEND: Phase III, Randomized Trial of Acalabrutinib Versus Idelalisib Plus Rituximab or Bendamustine Plus Rituximab in Relapsed or Refractory Chronic Lymphocytic Leukemia | Journal of Clinical Oncology | 2020 | 235 |
| 21 | The role of microRNAs in the pathogenesis of autoimmune diseases | Autoimmunity Reviews | 2016 | 226 |
| 22 | Multidrug-resistant bacterial infections in patients with decompensated cirrhosis and with acute-on-chronic liver failure in Europe | Journal of Hepatology | 2019 | 225 |
| 23 | EULAR definition of difficult-to-treat rheumatoid arthritis | Annals of the Rheumatic Diseases | 2021 | 224 |
| 24 | Vascular cognitive impairment neuropathology guidelines (VCING): the contribution of cerebrovascular pathology to cognitive impairment | Brain | 2016 | 220 |
| 25 | Mitochondrial Dysfunction Increases Allergic Airway Inflammation | Journal of Immunology | 2009 | 218 |
| 26 | The Role of Nutraceuticals in Statin Intolerant Patients | Journal of the American College of Cardiology | 2018 | 216 |
| 27 | Programmed necrotic cell death of macrophages: Focus on pyroptosis, necroptosis, and parthanatos | Redox Biology | 2019 | 212 |
| 28 | Consensus Statement on Perioperative Use of Neuromuscular Monitoring | Anesthesia and Analgesia | 2018 | 207 |
| 29 | Lipid lowering nutraceuticals in clinical practice: position paper from an International Lipid Expert Panel | Archives of Medical Science | 2017 | 206 |
| 30 | Ropeginterferon alfa-2b versus standard therapy for polycythaemia vera (PROUD-PV and CONTINUATION-PV): a randomised, non-inferiority, phase 3 trial and its extension study | Lancet Haematology,the | 2020 | 199 |
| 31 | The continuous heart failure spectrum: moving beyond an ejection fraction classification | European Heart Journal | 2019 | 195 |
| 32 | The Transcription Factor STAT6 Mediates Direct Repression of Inflammatory Enhancers and Limits Activation of Alternatively Polarized Macrophages | Immunity | 2018 | 185 |
| 33 | SUCCOR study: an international European cohort observational study comparing minimally invasive surgery versus open abdominal radical hysterectomy in patients with stage IB1 cervical cancer | International Journal of Gynecological Cancer | 2020 | 169 |
| 34 | Empagliflozin improves endothelial and cardiomyocyte function in human heart failure with preserved ejection fraction via reduced pro-inflammatory-oxidative pathways and protein kinase Gα oxidation | Cardiovascular Research | 2021 | 167 |
| 35 | Efficacy and Safety of the Biosimilar Infliximab CT-P13 Treatment in Inflammatory Bowel Diseases: A Prospective, Multicentre, Nationwide Cohort | Journal of Crohn's and Colitis | 2016 | 164 |
| 36 | Circulating cell-free nucleic acids: characteristics and applications | European Journal of Human Genetics | 2018 | 163 |
| 37 | Overview of the current status of familial hypercholesterolaemia care in over 60 countries - The EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC) | Atherosclerosis | 2018 | 163 |
| 38 | Chondrosenescence: Definition, hallmarks and potential role in the pathogenesis of osteoarthritis | Maturitas | 2015 | 162 |
| 39 | Understanding FRET as a Research Tool for Cellular Studies | International Journal of Molecular Sciences | 2015 | 158 |
| 40 | The Therapeutic Potentials of Ayahuasca: Possible Effects against Various Diseases of Civilization | Frontiers in Pharmacology | 2016 | 157 |
| 41 | Rheumatoid arthritis and metabolic syndrome | Nature Reviews Rheumatology | 2014 | 154 |
| 42 | ADP‐ribosyltransferases, an update on function and nomenclature | FEBS Journal | 2022 | 150 |
| 43 | Formation of a protein corona on the surface of extracellular vesicles in blood plasma | Journal of Extracellular Vesicles | 2021 | 150 |
| 44 | PREDICT identifies precipitating events associated with the clinical course of acutely decompensated cirrhosis | Journal of Hepatology | 2021 | 149 |
| 45 | Highly Dynamic Transcriptional Signature of Distinct Macrophage Subsets during Sterile Inflammation, Resolution, and Tissue Repair | Journal of Immunology | 2016 | 147 |
| 46 | Switch to natalizumab versus fingolimod in active relapsing–remitting multiple sclerosis | Annals of Neurology | 2015 | 143 |
| 47 | Beta-lactam compounds as apparently uncompetitive inhibitors of HIV-1 protease | Bioorganic and Medicinal Chemistry Letters | 2005 | 141 |
| 48 | Aloe vera downregulates LPS-induced inflammatory cytokine production and expression of NLRP3 inflammasome in human macrophages | Molecular Immunology | 2013 | 137 |
| 49 | Treatment effectiveness of alemtuzumab compared with natalizumab, fingolimod, and interferon beta in relapsing-remitting multiple sclerosis: a cohort study | Lancet Neurology, The | 2017 | 134 |
| 50 | Cannabinoid Signaling in the Skin: Therapeutic Potential of the “C(ut)annabinoid” System | Molecules | 2019 | 134 |
