| # | Title | Journal | Year | Citations |
|---|
| 1 | Multiple sclerosis | Lancet, The | 2018 | 1,204 |
| 2 | Tuning Out the Noise: Limbic-Auditory Interactions in Tinnitus | Neuron | 2010 | 630 |
| 3 | Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients | Journal of Neuroinflammation | 2012 | 593 |
| 4 | Intrathecal pathogenic anti–aquaporin‐4 antibodies in early neuromyelitis optica | Annals of Neurology | 2009 | 516 |
| 5 | Update on the diagnosis and treatment of neuromyelitis optica: Recommendations of the Neuromyelitis Optica Study Group (NEMOS) | Journal of Neurology | 2014 | 494 |
| 6 | Peripheral neuropathic pain: a mechanism-related organizing principle based on sensory profiles | Pain | 2017 | 462 |
| 7 | ECTRIMS/EAN Guideline on the pharmacological treatment of people with multiple sclerosis | Multiple Sclerosis Journal | 2018 | 458 |
| 8 | Interleukin-6: designing specific therapeutics for a complex cytokine | Nature Reviews Drug Discovery | 2018 | 440 |
| 9 | EFNS guidelines on diagnosis and management of neuromyelitis optica | European Journal of Neurology | 2010 | 376 |
| 10 | Potassium Channel KIR4.1 as an Immune Target in Multiple Sclerosis | New England Journal of Medicine | 2012 | 314 |
| 11 | Class II HLA interactions modulate genetic risk for multiple sclerosis | Nature Genetics | 2015 | 312 |
| 12 | Trans-presentation of IL-6 by dendritic cells is required for the priming of pathogenic TH17 cells | Nature Immunology | 2017 | 311 |
| 13 | Antibodies to native myelin oligodendrocyte glycoprotein in children with inflammatory demyelinating central nervous system disease | Annals of Neurology | 2009 | 283 |
| 14 | Continuous T Cell Receptor Signals Maintain a Functional Regulatory T Cell Pool | Immunity | 2014 | 262 |
| 15 | Myelin-oligodendrocyte glycoprotein antibody-associated disease | Lancet Neurology, The | 2021 | 261 |
| 16 | Gabapentin for chronic neuropathic pain in adults | The Cochrane Library | 2020 | 226 |
| 17 | T cell responses in the central nervous system | Nature Reviews Immunology | 2017 | 219 |
| 18 | Robust, reproducible and quantitative analysis of thousands of proteomes by micro-flow LC–MS/MS | Nature Communications | 2020 | 218 |
| 19 | Nusinersen in adults with 5q spinal muscular atrophy: a non-interventional, multicentre, observational cohort study | Lancet Neurology, The | 2020 | 196 |
| 20 | CXCL13 is the major determinant for B cell recruitment to the CSF during neuroinflammation | Journal of Neuroinflammation | 2012 | 190 |
| 21 | A common neural basis for receptive and expressive communication of pleasant facial affect | NeuroImage | 2005 | 178 |
| 22 | The increasing incidence and prevalence of female multiple sclerosis—A critical analysis of potential environmental factors | Autoimmunity Reviews | 2011 | 174 |
| 23 | Subthalamic nucleus stimulation affects striato-anterior cingulate cortex circuit in a response conflict task: a PET study | Brain | 2002 | 164 |
| 24 | Stratifying patients with peripheral neuropathic pain based on sensory profiles: algorithm and sample size recommendations | Pain | 2017 | 150 |
| 25 | ECTRIMS/EAN guideline on the pharmacological treatment of people with multiple sclerosis | European Journal of Neurology | 2018 | 147 |
| 26 | Differential effects of fingolimod (FTY720) on immune cells in the CSF and blood of patients with MS | Neurology | 2011 | 146 |
| 27 | Uncoupling Malt1 Threshold Function from Paracaspase Activity Results in Destructive Autoimmune Inflammation | Cell Reports | 2014 | 133 |
| 28 | Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation | Science Advances | 2016 | 133 |
| 29 | Cerebrospinal fluid findings in COVID-19 patients with neurological symptoms | Journal of the Neurological Sciences | 2020 | 125 |
| 30 | Immunotherapies in neuromyelitis optica spectrum disorder: efficacy and predictors of response | Journal of Neurology, Neurosurgery and Psychiatry | 2017 | 123 |
| 31 | Transient Receptor Potential Channel Polymorphisms Are Associated with the Somatosensory Function in Neuropathic Pain Patients | PLoS ONE | 2011 | 123 |
| 32 | Protective Functions of Reactive Astrocytes Following Central Nervous System Insult | Frontiers in Immunology | 2020 | 122 |
| 33 | The clinical spectrum and immunobiology of parainfectious neuromyelitis optica (Devic) syndromes | Journal of Autoimmunity | 2010 | 121 |
| 34 | Immunological Aspects of Approved MS Therapeutics | Frontiers in Immunology | 2019 | 117 |
| 35 | HLA-DRB1∗0401 and HLA-DRB1∗0408 Are Strongly Associated with the Development of Antibodies against Interferon-β Therapy in Multiple Sclerosis | American Journal of Human Genetics | 2008 | 114 |
| 36 | Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells | Nature Communications | 2016 | 105 |
| 37 | Optical coherence tomography angiography indicates associations of the retinal vascular network and disease activity in multiple sclerosis | Multiple Sclerosis Journal | 2019 | 104 |
| 38 | High-risk plaque features can be detected in non-stenotic carotid plaques of patients with ischaemic stroke classified as cryptogenic using combined 18F-FDG PET/MR imaging | European Journal of Nuclear Medicine and Molecular Imaging | 2016 | 103 |
| 39 | Cortical pathology in multiple sclerosis detected by the T1/T2‐weighted ratio from routine magnetic resonance imaging | Annals of Neurology | 2017 | 102 |
| 40 | TNF-alpha induced NFκB signaling and p65 (RelA) overexpression repress Cldn5 promoter in mouse brain endothelial cells | Cytokine | 2012 | 96 |
| 41 | Cytokine and immune cell profiling in the cerebrospinal fluid of patients with neuro-inflammatory diseases | Journal of Neuroinflammation | 2019 | 96 |
| 42 | Zoonotic spillover infections with Borna disease virus 1 leading to fatal human encephalitis, 1999–2019: an epidemiological investigation | Lancet Infectious Diseases, The | 2020 | 96 |
| 43 | Retinal inner nuclear layer volume reflects response to immunotherapy in multiple sclerosis | Brain | 2016 | 95 |
| 44 | EEG entropy measures indicate decrease of cortical information processing in Disorders of Consciousness | Clinical Neurophysiology | 2016 | 95 |
| 45 | Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis | Cell | 2018 | 93 |
| 46 | Service-Based Survey of Dystonia in Munich | Neuroepidemiology | 2002 | 90 |
| 47 | IL-27 and IL-12 oppose pro-inflammatory IL-23 in CD4+ T cells by inducing Blimp1 | Nature Communications | 2014 | 90 |
| 48 | Effectors of Th1 and Th17 cells act on astrocytes and augment their neuroinflammatory properties | Journal of Neuroinflammation | 2017 | 88 |
| 49 | A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity | Acta Neuropathologica | 2019 | 87 |
| 50 | Differences in number, size and location of intracranial microembolic lesions after surgical versus endovascular treatment without protection device of carotid artery stenosis | Journal of Neurology | 2004 | 86 |
