| # | Title | Journal | Year | Citations |
|---|
| 1 | Physical Exercise Protects Against Alzheimer's Disease in 3xTg-AD Mice | Journal of Alzheimer's Disease | 2011 | 223 |
| 2 | Inbred Roman High- and Low-Avoidance Rats | Physiology and Behavior | 1999 | 204 |
| 3 | Modeling behavioral and neuronal symptoms of Alzheimer's disease in mice: A role for intraneuronal amyloid | Neuroscience and Biobehavioral Reviews | 2007 | 202 |
| 4 | The Trail Making Test | Assessment | 2017 | 201 |
| 5 | Mice lacking the adenosine A1 receptor are anxious and aggressive, but are normal learners with reduced muscle strength and survival rate | European Journal of Neuroscience | 2002 | 169 |
| 6 | Antidepressant Efficacy and Tolerability of Ketamine and Esketamine: A Critical Review | CNS Drugs | 2018 | 167 |
| 7 | Early-life handling stimulation and environmental enrichment | Pharmacology Biochemistry and Behavior | 2002 | 152 |
| 8 | Impaired short- and long-term memory in Ts65Dn mice, a model for Down syndrome | Neuroscience Letters | 1998 | 149 |
| 9 | Virtual Histology of Cortical Thickness and Shared Neurobiology in 6 Psychiatric Disorders | JAMA Psychiatry | 2021 | 136 |
| 10 | Characteristics of suicidal ideation that predict the transition to future suicide attempts in adolescents | Journal of Child Psychology and Psychiatry and Allied Disciplines | 2014 | 117 |
| 11 | The effects of the Spanish COVID-19 lockdown on people, their pets, and the human-animal bond | Journal of Veterinary Behavior: Clinical Applications and Research | 2020 | 117 |
| 12 | Working memory deficits in transgenic rats overexpressing human adenosine A2A receptors in the brain | Neurobiology of Learning and Memory | 2007 | 115 |
| 13 | Enduring effects of environmental enrichment on novelty seeking, saccharin and ethanol intake in two rat lines (RHA/Verh and RLA/Verh) differing in incentive-seeking behavior | Pharmacology Biochemistry and Behavior | 2002 | 112 |
| 14 | Assessing body awareness and autonomic reactivity: Factor structure and psychometric properties of the Body Perception Questionnaire‐Short Form (BPQ‐SF) | International Journal of Methods in Psychiatric Research | 2018 | 109 |
| 15 | Oxidative Stress Is a Central Target for Physical Exercise Neuroprotection Against Pathological Brain Aging | Journals of Gerontology - Series A Biological Sciences and Medical Sciences | 2016 | 106 |
| 16 | Enduring effects of environmental enrichment from weaning to adulthood on pituitary-adrenal function, pre-pulse inhibition and learning in male and female rats | Psychoneuroendocrinology | 2009 | 91 |
| 17 | Lenti‐GDNF Gene Therapy Protects Against Alzheimer's Disease‐Like Neuropathology in 3xTg‐AD Mice and MC65 Cells | CNS Neuroscience and Therapeutics | 2014 | 89 |
| 18 | SIRT1 Overexpression in Mouse Hippocampus Induces Cognitive Enhancement Through Proteostatic and Neurotrophic Mechanisms | Molecular Neurobiology | 2017 | 89 |
| 19 | Environmental enrichment effects in social investigation in rats are gender dependent | Behavioural Brain Research | 2006 | 88 |
| 20 | Melatonin plus physical exercise are highly neuroprotective in the 3xTg-AD mouse | Neurobiology of Aging | 2012 | 86 |
| 21 | Fearfulness and sex in F2 Roman rats: males display more fear though both sexes share the same fearfulness traits | Physiology and Behavior | 2003 | 84 |
| 22 | No effect of trait anxiety on differential fear conditioning or fear generalization | Biological Psychology | 2013 | 82 |
| 23 | Gray matter volume deficits and correlation with insight and negative symptoms in first-psychotic-episode subjects | Acta Psychiatrica Scandinavica | 2011 | 81 |
| 24 | Gender-Specific Neuroimmunoendocrine Aging in a Triple-Transgenic 3×Tg-AD Mouse Model for Alzheimer’s Disease and Its Relation with Longevity | NeuroImmunoModulation | 2008 | 79 |
| 25 | Hikikomori in Spain: A descriptive study | International Journal of Social Psychiatry | 2015 | 79 |
| 26 | Ovariectomy, a model of menopause in rodents, causes a premature aging of the nervous and immune systems | Journal of Neuroimmunology | 2010 | 74 |
| 27 | High sensitivity to punishment and low impulsivity in obsessive-compulsive patients with hoarding symptoms | Psychiatry Research | 2004 | 67 |
| 28 | Gender-Specific Neuroimmunoendocrine Response to Treadmill Exercise in 3xTg-AD Mice | International Journal of Alzheimer's Disease | 2010 | 67 |
| 29 | Attempted and completed suicide: Not what we expected? | Journal of Affective Disorders | 2013 | 67 |
| 30 | Learned fear, emotional reactivity and fear of heights: a factor analytic map from a large F2 intercross of Roman rat strains | Brain Research Bulletin | 2002 | 66 |
| 31 | Cognitive and emotional profiles of aged Alzheimer's disease (3×TgAD) mice: Effects of environmental enrichment and sexual dimorphism | Behavioural Brain Research | 2014 | 61 |
| 32 | Consortium neuroscience of attention deficit/hyperactivity disorder and autism spectrum disorder: The ENIGMA adventure | Human Brain Mapping | 2022 | 61 |
| 33 | Pregnancy and adolescence entail similar neuroanatomical adaptations: A comparative analysis of cerebral morphometric changes | Human Brain Mapping | 2019 | 60 |
| 34 | Mice lacking the adenosine A1 receptor have normal spatial learning and plasticity in the CA1 region of the hippocampus, but they habituate more slowly | Synapse | 2005 | 57 |
| 35 | Galanin neurons in the intermediate nucleus (InM) of the human hypothalamus in relation to sex, age, and gender identity | Journal of Comparative Neurology | 2011 | 54 |
| 36 | Personality characteristics in obsessive-compulsive disorder and individuals with subclinical obsessive-compulsive problems | British Journal of Clinical Psychology | 2004 | 53 |
| 37 | Physical exercise neuroprotects ovariectomized 3xTg-AD mice through BDNF mechanisms | Psychoneuroendocrinology | 2014 | 53 |
| 38 | Convergent and Discriminant Validity of the Yale-Brown Obsessive-Compulsive Scale Symptom Checklist | Psychotherapy and Psychosomatics | 2004 | 51 |
| 39 | Localization of cholesterol, amyloid and glia in Alzheimer’s disease transgenic mouse brain tissue using time-of-flight secondary ion mass spectrometry (ToF-SIMS) and immunofluorescence imaging | Acta Neuropathologica | 2013 | 48 |
| 40 | The psychogenetically selected Roman rat lines differ in the susceptibility to develop amphetamine sensitization | Behavioural Brain Research | 2005 | 47 |
| 41 | The Pain Assessment in Impaired Cognition scale (PAIC15): A multidisciplinary and international approach to develop and test a meta‐tool for pain assessment in impaired cognition, especially dementia | European Journal of Pain | 2020 | 47 |
| 42 | Peripheral immune system and neuroimmune communication impairment in a mouse model of Alzheimer's disease | Annals of the New York Academy of Sciences | 2012 | 46 |
| 43 | Combination of adenosine A1 and A2A receptor blocking agents induces caffeine-like locomotor stimulation in mice | European Neuropsychopharmacology | 2006 | 45 |
| 44 | The Cholinergic Antagonist Gymnodimine Improves Aβ and Tau Neuropathology in an <i>in Vitro</i> Model of Alzheimer Disease | Cellular Physiology and Biochemistry | 2011 | 45 |
| 45 | Prepulse inhibition predicts spatial working memory performance in the inbred Roman high- and low-avoidance rats and in genetically heterogeneous NIH-HS rats: relevance for studying pre-attentive and cognitive anomalies in schizophrenia | Frontiers in Behavioral Neuroscience | 2015 | 44 |
| 46 | Cognitive and emotional alterations in young Alzheimer's disease (3xTgAD) mice: Effects of neonatal handling stimulation and sexual dimorphism | Behavioural Brain Research | 2015 | 42 |
| 47 | Prevalence and influence of cys407* Grm2 mutation in Hannover-derived Wistar rats: mGlu2 receptor loss links to alcohol intake, risk taking and emotional behaviour | Neuropharmacology | 2017 | 42 |
| 48 | A 12-month study of the hikikomori syndrome of social withdrawal: Clinical characterization and different subtypes proposal | Psychiatry Research | 2018 | 42 |
| 49 | Epidemiology of Dog and Cat Abandonment in Spain (2008–2013) | Animals | 2015 | 41 |
| 50 | Internet-based self-help treatment for panic disorder: a randomized controlled trial comparing mandatory versus optional complementary psychological support | Cognitive Behaviour Therapy | 2016 | 41 |
