Structural studies by electron tomography: from cells to molecules | Annual Review of Biochemistry | 2005 | 551 |
SUMO-modified PCNA recruits Srs2 to prevent recombination during S phase | Nature | 2005 | 487 |
A series of ubiquitin binding factors connects CDC48/p97 to substrate multiubiquitylation and proteasomal targeting | Cell | 2005 | 427 |
The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1 | Oncogene | 2005 | 418 |
TOM software toolbox: acquisition and analysis for electron tomography | Journal of Structural Biology | 2005 | 367 |
Membrane-bound Ubx2 recruits Cdc48 to ubiquitin ligases and their substrates to ensure efficient ER-associated protein degradation | Nature Cell Biology | 2005 | 234 |
Cdk1/Erk2- and Plk1-dependent phosphorylation of a centrosome protein, Cep55, is required for its recruitment to midbody and cytokinesis | Developmental Cell | 2005 | 230 |
Cryo-electron tomography reveals the cytoskeletal structure of Spiroplasma melliferum | Science | 2005 | 202 |
Proteome analysis of the human mitotic spindle | Molecular and Cellular Proteomics | 2005 | 201 |
Calcium triggers exit from meiosis II by targeting the APC/C inhibitor XErp1 for degradation | Nature | 2005 | 191 |
Mutual inhibition of separase and Cdk1 by two-step complex formation | Molecular Cell | 2005 | 154 |
Down-regulation of c-Fos/c-Jun AP-1 dimer activity by sumoylation | Molecular and Cellular Biology | 2005 | 153 |
Xenopus polo-like kinase Plx1 regulates XErp1, a novel inhibitor of APC/C activity | Genes and Development | 2005 | 143 |
Pathogenic mutations inactivate parkin by distinct mechanisms | Journal of Neurochemistry | 2005 | 91 |
The unique C-terminal tail of the mitogen-activated protein kinase ERK5 regulates its activation and nuclear shuttling | Journal of Biological Chemistry | 2005 | 86 |
Viral oncoproteins E1A and E7 and cellular LxCxE proteins repress SUMO modification of the retinoblastoma tumor suppressor | Oncogene | 2005 | 82 |
GPCR-induced migration of breast carcinoma cells depends on both EGFR signal transactivation and EGFR-independent pathways | Biological Chemistry | 2005 | 80 |
Coordinate regulation of the mother centriole component nlp by nek2 and plk1 protein kinases | Molecular and Cellular Biology | 2005 | 74 |
From proteomic inventory to architecture | FEBS Letters | 2005 | 70 |
VAT, the thermoplasma homolog of mammalian p97/VCP, is an N domain-regulated protein unfoldase | Journal of Biological Chemistry | 2005 | 59 |
Optically transparent porous medium for nondestructive studies of microbial biofilm architecture and transport dynamics | Applied and Environmental Microbiology | 2005 | 53 |
Securin is not required for chromosomal stability in human cells | PLoS Biology | 2005 | 45 |
Anti-HER-3 MAbs inhibit HER-3-mediated signaling in breast cancer cell lines resistant to anti-HER-2 antibodies | International Journal of Cancer | 2005 | 40 |
Abl-kinase-sensitive levels of ERK5 and its intrinsic basal activity contribute to leukaemia cell survival | EMBO Reports | 2005 | 35 |
High-content screening and profiling of drug activity in an automated centrosome-duplication assay | ChemBioChem | 2005 | 33 |