Global Landscape and Dynamics of Parkin and USP30-Dependent Ubiquitylomes in iNeurons during Mitophagic Signaling | Molecular Cell | 2020 | 69 |
A streamlined mass spectrometry-based proteomics workflow for large-scale FFPE tissue analysis | Journal of Pathology | 2020 | 50 |
cAMP-dependent regulation of HCN4 controls the tonic entrainment process in sinoatrial node pacemaker cells | Nature Communications | 2020 | 29 |
Cell-to-cell transmission of C9orf72 poly-(Gly-Ala) triggers key features of ALS/FTD | EMBO Journal | 2020 | 27 |
A precisely positioned MED12 activation helix stimulates CDK8 kinase activity | Proceedings of the National Academy of Sciences of the United States of America | 2020 | 25 |
Integrin-Mediated Focal Anchorage Drives Epithelial Zippering during Mouse Neural Tube Closure | Developmental Cell | 2020 | 23 |
MiT/TFE factors control ER-phagy via transcriptional regulation of FAM134B | EMBO Journal | 2020 | 23 |
A Cell-Autonomous Signature of Dysregulated Protein Phosphorylation Underlies Muscle Insulin Resistance in Type 2 Diabetes | Cell Metabolism | 2020 | 21 |
The integrin-linked kinase is required for chemokine-triggered high-affinity conformation of the neutrophil β2-integrin LFA-1 | Blood | 2020 | 18 |
Dissecting distinct proteolytic activities of FMDV Lpro implicates cleavage and degradation of RLR signaling proteins, not its deISGylase/DUB activity, in type I interferon suppression | PLoS Pathogens | 2020 | 16 |
Protease-activated receptor signalling initiates αβ-integrin-mediated adhesion in non-haematopoietic cells | Nature Materials | 2020 | 10 |
Mice Lacking the Matrilin Family of Extracellular Matrix Proteins Develop Mild Skeletal Abnormalities and Are Susceptible to Age-Associated Osteoarthritis | International Journal of Molecular Sciences | 2020 | 9 |
Multiparametric Assays for Accelerating Early Drug Discovery | Trends in Pharmacological Sciences | 2020 | 8 |
Fam20C regulates protein secretion by Cab45 phosphorylation | Journal of Cell Biology | 2020 | 7 |
Kindlin-3 loss curbs chronic myeloid leukemia in mice by mobilizing leukemic stem cells from protective bone marrow niches | Proceedings of the National Academy of Sciences of the United States of America | 2020 | 7 |
Cholesterol sensing by CD81 is important for hepatitis C virus entry | Journal of Biological Chemistry | 2020 | 6 |
Activation by substoichiometric inhibition | Proceedings of the National Academy of Sciences of the United States of America | 2020 | 5 |
Rabgap1 promotes recycling of active β1 integrins to support effective cell migration | Journal of Cell Science | 2020 | 5 |
Allosteric regulation through a switch element in the autophagy E2, Atg3 | Autophagy | 2020 | 3 |
SHP1 regulates a STAT6-ITGB3 axis in FLT3ITD-positive AML cells | Leukemia | 2020 | 3 |
The Origins of Organellar Mapping by Protein Correlation Profiling | Proteomics | 2020 | 3 |
Sequencing of the First Draft of the Human Acetylome | Clinical Chemistry | 2020 | 1 |
β1 Integrin regulates convergent extension in mouse notogenesis, ensures notochord integrity and the morphogenesis of vertebrae and intervertebral discs | Development (Cambridge) | 2020 | 1 |