| # | Title | Journal | Year | Citations |
|---|
| 1 | Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease | Nature | 2003 | 1,980 |
| 2 | The changing global patterns of female breast cancer incidence and mortality | Breast Cancer Research | 2004 | 724 |
| 3 | Caesarean section is associated with an increased risk of childhood-onset type 1 diabetes mellitus: a meta-analysis of observational studies | Diabetologia | 2008 | 496 |
| 4 | Birthweight, body-mass index in middle age, and incident coronary heart disease | Lancet, The | 1996 | 480 |
| 5 | Incidence of childhood-onset insulin-dependent diabetes mellitus: the EURODIAB ACE study | Lancet, The | 1992 | 423 |
| 6 | Associations of circulating C-reactive protein and interleukin-6 with cancer risk: findings from two prospective cohorts and a meta-analysis | Cancer Causes and Control | 2009 | 259 |
| 7 | The methionine synthase reductase (MTRR) A66G polymorphism is a novel genetic determinant of plasma homocysteine concentrations | Atherosclerosis | 2001 | 233 |
| 8 | Methionine synthase D919G polymorphism is a significant but modest determinant of circulating homocysteine concentrations | Genetic Epidemiology | 1999 | 218 |
| 9 | Geographical variation of presentation at diagnosis of Type I diabetes in children: the EURODIAB Study | Diabetologia | 2001 | 198 |
| 10 | Lipoprotein (a) as a predictor of coronary heart disease: the PRIME Study | Atherosclerosis | 2002 | 196 |
| 11 | Early mortality in EURODIAB population-based cohorts of type 1 diabetes diagnosed in childhood since 1989 | Diabetologia | 2007 | 171 |
| 12 | Acute Complications and Drug Misuse Are Important Causes of Death for Children and Young Adults With Type 1 Diabetes | Diabetes Care | 2008 | 161 |
| 13 | Epidemiology of childhood IDDM in Northern Ireland 1989?1994: Low incidence in areas with highest population density and most household crowding | Diabetologia | 1996 | 156 |
| 14 | Sequence Diversity in 36 Candidate Genes for Cardiovascular Disorders | American Journal of Human Genetics | 1999 | 152 |
| 15 | Carbonated Soft Drink Consumption and Bone Mineral Density in Adolescence: The Northern Ireland Young Hearts Project | Journal of Bone and Mineral Research | 2003 | 145 |
| 16 | Trends in coronary risk factors in the WHO MONICA Project | International Journal of Epidemiology | 2001 | 138 |
| 17 | Rapid Early Growth Is Associated With Increased Risk of Childhood Type 1 Diabetes in Various European Populations | Diabetes Care | 2002 | 133 |
| 18 | Apolipoprotein E serum concentration and polymorphism in six European countries: the ApoEurope Project | Atherosclerosis | 2000 | 132 |
| 19 | Is childhood-onset Type I diabetes a wealth-related disease? An ecological analysis of European incidence rates | Diabetologia | 2001 | 129 |
| 20 | Leisure-time physical activity and regular walking or cycling to work are associated with adiposity and 5 y weight gain in middle-aged men: the PRIME Study | International Journal of Obesity | 2001 | 115 |
| 21 | MORGAM (an international pooling of cardiovascular cohorts) | International Journal of Epidemiology | 2004 | 105 |
| 22 | Impact of Cough Across Different Chronic Respiratory Diseases | Chest | 2008 | 104 |
| 23 | Neovascular Age-Related Macular Degeneration Risk Based on CFH, LOC387715/HTRA1, and Smoking | PLoS Medicine | 2007 | 101 |
| 24 | The Genetics of Coronary Heart Disease: The Contribution of Twin Studies | Twin Research and Human Genetics | 2003 | 98 |
| 25 | Frequency of fruit and vegetable consumption and coronary heart disease in France and Northern Ireland: the PRIME study | British Journal of Nutrition | 2004 | 96 |
| 26 | Parental recall of birthweight: a good proxy for recorded birthweight? | European Journal of Epidemiology | 2000 | 94 |
| 27 | Randomised clinical trial: Helicobacter pylori eradication is associated with a significantly increased body mass index in a placebo-controlled study | Alimentary Pharmacology and Therapeutics | 2011 | 93 |
| 28 | The Association of C-Reactive Protein and CRP Genotype with Coronary Heart Disease: Findings from Five Studies with 4,610 Cases amongst 18,637 Participants | PLoS ONE | 2008 | 90 |
| 29 | Education, socioeconomic and lifestyle factors, and risk of coronary heart disease: the PRIME Study | International Journal of Epidemiology | 2005 | 87 |
| 30 | Endovascular Ruptured Abdominal Aortic Aneurysm Repair (EVRAR): A Systematic Review | European Journal of Vascular and Endovascular Surgery | 2007 | 84 |
| 31 | Residual cardiovascular risk in treated hypertension and hyperlipidaemia: the PRIME Study | Journal of Human Hypertension | 2010 | 81 |
| 32 | Cardiovascular risk factors and alcohol consumption in France and Northern Ireland | Atherosclerosis | 1995 | 78 |
| 33 | Randomized Controlled Trial of an Early Discharge Rehabilitation Service | Stroke | 2004 | 71 |
| 34 | Increasing inequalities in health: Is it an artefact caused by the selective movement of people? | Social Science and Medicine | 2007 | 69 |
| 35 | Mental health in Northern Ireland: have "the Troubles" made it worse? | Journal of Epidemiology and Community Health | 2003 | 67 |
| 36 | Serum copper and zinc in random samples of the population of Northern Ireland | American Journal of Clinical Nutrition | 1992 | 62 |
| 37 | Acute Asthma Exacerbations and Air Pollutants in Children Living in Belfast, Northern Ireland | Archives of Environmental Health | 2001 | 61 |
| 38 | Plasma fibrinogen explains much of the difference in risk of coronary heart disease between France and Northern Ireland. The PRIME study | Atherosclerosis | 2003 | 61 |
| 39 | Haemostatic/inflammatory markers predict 10-year risk of IHD at least as well as lipids: the Caerphilly collaborative studies | European Heart Journal | 2004 | 60 |
| 40 | Age-related changes in energy efficiency of gait, activity, and participation in children with cerebral palsy | Developmental Medicine and Child Neurology | 2011 | 59 |
| 41 | Clinical and metabolic effects of gluten free diet in children with type 1 diabetes and coeliac disease | Pediatric Diabetes | 2011 | 57 |
| 42 | Trends in blood pressure over 10 years in adolescents: analyses of cross sectional surveys in the Northern Ireland Young Hearts project | BMJ: British Medical Journal | 2004 | 55 |
| 43 | Type 2 diabetes in grandparents and birth weight in offspring and grandchildren in the ALSPAC study | Journal of Epidemiology and Community Health | 2004 | 54 |
| 44 | Impact of Helicobacter pylori eradication on dyspepsia, health resource use, and quality of life in the Bristol helicobacter project: randomised controlled trial | BMJ: British Medical Journal | 2006 | 54 |
| 45 | High density lipoprotein subfractions and the risk of coronary heart disease: 9-years follow-up in the Caerphilly Study | Atherosclerosis | 2003 | 53 |
| 46 | Association between the LPL-D9N mutation in the lipoprotein lipase gene and plasma lipid traits in myocardial infarction survivors from the ECTIM study | Atherosclerosis | 1996 | 52 |
| 47 | The MTHFR C677T polymorphism is associated with depressive episodes in patients from Northern Ireland | Journal of Psychopharmacology | 2004 | 51 |
| 48 | Antidepressant prescribing and suicide rate in Northern Ireland | European Psychiatry | 2003 | 50 |
| 49 | Potentially malignant oral lesions in Northern Ireland: a 20-year population-based perspective of malignant transformation | Oral Diseases | 2001 | 49 |
| 50 | Insulin resistance and depressive symptoms in middle aged men: findings from the Caerphilly prospective cohort study | BMJ: British Medical Journal | 2005 | 49 |
