| # | Title | Journal | Year | Citations |
|---|
| 1 | Third European Evidence-based Consensus on Diagnosis and Management of Ulcerative Colitis. Part 1: Definitions, Diagnosis, Extra-intestinal Manifestations, Pregnancy, Cancer Surveillance, Surgery, and Ileo-anal Pouch Disorders | Journal of Crohn's and Colitis | 2017 | 1,324 |
| 2 | Towards the introduction of the ‘Immunoscore’ in the classification of malignant tumours | Journal of Pathology | 2014 | 1,151 |
| 3 | Defective Lipolysis and Altered Energy Metabolism in Mice Lacking Adipose Triglyceride Lipase | Science | 2006 | 1,135 |
| 4 | Endoscopic submucosal dissection: European Society of Gastrointestinal Endoscopy (ESGE) Guideline | Endoscopy | 2015 | 1,112 |
| 5 | Magnetic resonance imaging of the breast: Recommendations from the EUSOMA working group | European Journal of Cancer | 2010 | 813 |
| 6 | Characterization of HULC, a Novel Gene With Striking Up-Regulation in Hepatocellular Carcinoma, as Noncoding RNA | Gastroenterology | 2007 | 725 |
| 7 | Cancer classification using the Immunoscore: a worldwide task force | Journal of Translational Medicine | 2012 | 676 |
| 8 | Germline mutations in BAP1 predispose to melanocytic tumors | Nature Genetics | 2011 | 662 |
| 9 | Alcoholic liver disease | Nature Reviews Disease Primers | 2018 | 660 |
| 10 | Recommendations for reporting tumor budding in colorectal cancer based on the International Tumor Budding Consensus Conference (ITBCC) 2016 | Modern Pathology | 2017 | 652 |
| 11 | Causability and explainability of artificial intelligence in medicine | Wiley Interdisciplinary Reviews: Data Mining and Knowledge Discovery | 2019 | 647 |
| 12 | ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1 | Nature Medicine | 2011 | 612 |
| 13 | Modern Age Pathology of Pulmonary Arterial Hypertension | American Journal of Respiratory and Critical Care Medicine | 2012 | 501 |
| 14 | Cognitive impairment by antibiotic-induced gut dysbiosis: Analysis of gut microbiota-brain communication | Brain, Behavior, and Immunity | 2016 | 500 |
| 15 | Adipose Triglyceride Lipase Contributes to Cancer-Associated Cachexia | Science | 2011 | 475 |
| 16 | Increased neutrophil-lymphocyte ratio is a poor prognostic factor in patients with primary operable and inoperable pancreatic cancer | British Journal of Cancer | 2013 | 423 |
| 17 | Mechanical characterization of human brain tissue | Acta Biomaterialia | 2017 | 423 |
| 18 | Progression and metastasis of lung cancer | Cancer and Metastasis Reviews | 2016 | 373 |
| 19 | A dual role for autophagy in a murine model of lung cancer | Nature Communications | 2014 | 369 |
| 20 | Single lamellar mechanics of the human lumbar anulus fibrosus | Biomechanics and Modeling in Mechanobiology | 2005 | 362 |
| 21 | A Lymphotoxin-Driven Pathway to Hepatocellular Carcinoma | Cancer Cell | 2009 | 345 |
| 22 | Anisotropic Mechanical Properties of Tissue Components in Human Atherosclerotic Plaques | Journal of Biomechanical Engineering | 2004 | 330 |
| 23 | Brain tissue deforms similarly to filled elastomers and follows consolidation theory | Journal of the Mechanics and Physics of Solids | 2006 | 315 |
| 24 | Heterogeneity of Prostate-Specific Membrane Antigen (PSMA) Expression in Prostate Carcinoma with Distant Metastasis | Pathology and Oncology Research | 2009 | 311 |
| 25 | Tumor-associated copy number changes in the circulation of patients with prostate cancer identified through whole-genome sequencing | Genome Medicine | 2013 | 306 |
| 26 | From Mallory to Mallory–Denk bodies: What, how and why? | Experimental Cell Research | 2007 | 304 |
| 27 | Inferring expressed genes by whole-genome sequencing of plasma DNA | Nature Genetics | 2016 | 295 |
| 28 | Determination of the layer-specific distributed collagen fibre orientations in human thoracic and abdominal aortas and common iliac arteries | Journal of the Royal Society Interface | 2012 | 288 |
| 29 | 24-norUrsodeoxycholic Acid Is Superior to Ursodeoxycholic Acid in the Treatment of Sclerosing Cholangitis in Mdr2 (Abcb4) Knockout Mice | Gastroenterology | 2006 | 282 |
| 30 | Heterogeneity in age-related white matter changes | Acta Neuropathologica | 2011 | 271 |
| 31 | KRAS mutation testing for predicting response to anti-EGFR therapy for colorectal carcinoma: proposal for an European quality assurance program | Virchows Archiv Fur Pathologische Anatomie Und Physiologie Und Fur Klinische Medizin | 2008 | 269 |
| 32 | In search of a novel target — Phosphatidylserine exposed by non-apoptotic tumor cells and metastases of malignancies with poor treatment efficacy | Biochimica Et Biophysica Acta - Biomembranes | 2011 | 269 |
| 33 | Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors | Nature Communications | 2017 | 260 |
| 34 | Alterations in Gut Microbiome Composition and Barrier Function Are Associated with Reproductive and Metabolic Defects in Women with Polycystic Ovary Syndrome (PCOS): A Pilot Study | PLoS ONE | 2017 | 253 |
| 35 | Pulmonary pathology and COVID-19: lessons from autopsy. The experience of European Pulmonary Pathologists | Virchows Archiv Fur Pathologische Anatomie Und Physiologie Und Fur Klinische Medizin | 2020 | 237 |
| 36 | Ursodeoxycholic acid exerts farnesoid X receptor-antagonistic effects on bile acid and lipid metabolism in morbid obesity | Journal of Hepatology | 2015 | 236 |
| 37 | Ballooned hepatocytes in steatohepatitis: The value of keratin immunohistochemistry for diagnosis | Journal of Hepatology | 2008 | 218 |
| 38 | Liver cancer initiation is controlled by AP-1 through SIRT6-dependent inhibition of survivin | Nature Cell Biology | 2012 | 218 |
| 39 | Biomechanical properties and microstructure of human ventricular myocardium | Acta Biomaterialia | 2015 | 217 |
| 40 | Alteration of Intestinal Dysbiosis by Fecal Microbiota Transplantation Does not Induce Remission in Patients with Chronic Active Ulcerative Colitis | Inflammatory Bowel Diseases | 2013 | 216 |
| 41 | Standardization of pathologic evaluation and reporting of postneoadjuvant specimens in clinical trials of breast cancer: recommendations from an international working group | Modern Pathology | 2015 | 205 |
| 42 | Intramural and extramural vascular invasion in colorectal cancer | Cancer | 2012 | 204 |
| 43 | Safety and efficacy of regorafenib in patients with advanced soft tissue sarcoma (REGOSARC): a randomised, double-blind, placebo-controlled, phase 2 trial | Lancet Oncology, The | 2016 | 200 |
| 44 | Histological parameters and alcohol abstinence determine long-term prognosis in patients with alcoholic liver disease | Journal of Hepatology | 2017 | 195 |
| 45 | DNA methylation heterogeneity defines a disease spectrum in Ewing sarcoma | Nature Medicine | 2017 | 193 |
| 46 | Layer-Specific 3D Residual Deformations of Human Aortas with Non-Atherosclerotic Intimal Thickening | Annals of Biomedical Engineering | 2007 | 192 |
| 47 | Layer-specific damage experiments and modeling of human thoracic and abdominal aortas with non-atherosclerotic intimal thickening | Journal of the Mechanical Behavior of Biomedical Materials | 2012 | 186 |
| 48 | Effects of high doses of vitamin D3 on mucosa-associated gut microbiome vary between regions of the human gastrointestinal tract | European Journal of Nutrition | 2016 | 185 |
| 49 | Effects of n-3 fish oil on metabolic and histological parameters in NASH: A double-blind, randomized, placebo-controlled trial | Journal of Hepatology | 2015 | 182 |
| 50 | Recommendations for standardized pathological characterization of residual disease for neoadjuvant clinical trials of breast cancer by the BIG-NABCG collaboration | Annals of Oncology | 2015 | 177 |
