| # | Title | Journal | Year | Citations |
|---|
| 1 | New genetic loci link adipose and insulin biology to body fat distribution | Nature | 2015 | 1,328 |
| 2 | Defective Lipolysis and Altered Energy Metabolism in Mice Lacking Adipose Triglyceride Lipase | Science | 2006 | 1,135 |
| 3 | Cardioprotection and lifespan extension by the natural polyamine spermidine | Nature Medicine | 2016 | 801 |
| 4 | Exercise training in heart failure: from theory to practice. A consensus document of the Heart Failure Association and the European Association for Cardiovascular Prevention and Rehabilitation | European Journal of Heart Failure | 2011 | 580 |
| 5 | Epidemiology and clinical course of heart failure with preserved ejection fraction | European Journal of Heart Failure | 2011 | 569 |
| 6 | Exercise Training Improves Exercise Capacity and Diastolic Function in Patients With Heart Failure With Preserved Ejection Fraction | Journal of the American College of Cardiology | 2011 | 564 |
| 7 | New strategies for heart failure with preserved ejection fraction: the importance of targeted therapies for heart failure phenotypes | European Heart Journal | 2014 | 304 |
| 8 | Developing Therapies for Heart Failure With Preserved Ejection Fraction | JACC: Heart Failure | 2014 | 267 |
| 9 | Adherence of heart failure patients to exercise: barriers and possible solutions | European Journal of Heart Failure | 2012 | 263 |
| 10 | Vitamin D and cardiovascular disease prevention | Nature Reviews Cardiology | 2016 | 250 |
| 11 | Cold-Induced Thermogenesis Depends on ATGL-Mediated Lipolysis in Cardiac Muscle, but Not Brown Adipose Tissue | Cell Metabolism | 2017 | 242 |
| 12 | Effect of Home-Based Telemonitoring Using Mobile Phone Technology on the Outcome of Heart Failure Patients After an Episode of Acute Decompensation: Randomized Controlled Trial | Journal of Medical Internet Research | 2009 | 227 |
| 13 | Nucleocytosolic Depletion of the Energy Metabolite Acetyl-Coenzyme A Stimulates Autophagy and Prolongs Lifespan | Cell Metabolism | 2014 | 221 |
| 14 | Vitamin D and mortality: Individual participant data meta-analysis of standardized 25-hydroxyvitamin D in 26916 individuals from a European consortium | PLoS ONE | 2017 | 219 |
| 15 | Biomechanical properties and microstructure of human ventricular myocardium | Acta Biomaterialia | 2015 | 217 |
| 16 | Changes in m6A RNA methylation contribute to heart failure progression by modulating translation | European Journal of Heart Failure | 2020 | 193 |
| 17 | Clinical outcome endpoints in heart failure trials: a European Society of Cardiology Heart Failure Association consensus document | European Journal of Heart Failure | 2013 | 182 |
| 18 | Apixaban in patients at risk of stroke undergoing atrial fibrillation ablation | European Heart Journal | 2018 | 181 |
| 19 | Autophagy in Cardiovascular Aging | Circulation Research | 2018 | 171 |
| 20 | Effects of the long‐term administration of nebivolol on the clinical symptoms, exercise capacity, and left ventricular function of patients with diastolic dysfunction: results of the ELANDD study | European Journal of Heart Failure | 2012 | 158 |
| 21 | Standardization of Fractional Flow Reserve Measurements | Journal of the American College of Cardiology | 2016 | 157 |
| 22 | Galectin‐3 in patients with heart failure with preserved ejection fraction: results from the Aldo‐DHF trial | European Journal of Heart Failure | 2015 | 146 |
| 23 | Aldosterone and parathyroid hormone interactions as mediators of metabolic and cardiovascular disease | Metabolism: Clinical and Experimental | 2014 | 133 |
| 24 | The cGMP Signaling Pathway as a Therapeutic Target in Heart Failure With Preserved Ejection Fraction | Journal of the American Heart Association | 2013 | 131 |
| 25 | Novel Genetic Markers Associate With Atrial Fibrillation Risk in Europeans and Japanese | Journal of the American College of Cardiology | 2014 | 127 |
| 26 | The novel biomarker growth differentiation factor 15 in heart failure with normal ejection fraction | European Journal of Heart Failure | 2010 | 123 |
| 27 | Rationale and design of the SOluble guanylate Cyclase stimulatoR in heArT failurE Studies (SOCRATES) | European Journal of Heart Failure | 2014 | 119 |
| 28 | Association of glucose metabolism with diastolic function along the diabetic continuum | Diabetologia | 2010 | 117 |
| 29 | Baseline Characteristics of Patients With Heart Failure and Preserved Ejection Fraction in the PARAGON-HF Trial | Circulation: Heart Failure | 2018 | 117 |
| 30 | Zinc Inhibits Phosphate-Induced Vascular Calcification through TNFAIP3-Mediated Suppression of NF-κB | Journal of the American Society of Nephrology: JASN | 2018 | 109 |
| 31 | Nicotinamide for the treatment of heart failure with preserved ejection fraction | Science Translational Medicine | 2021 | 109 |
| 32 | Contribution of comorbidities to functional impairment is higher in heart failure with preserved than with reduced ejection fraction | Clinical Research in Cardiology | 2011 | 101 |
| 33 | Blunted frequency-dependent upregulation of cardiac output is related to impaired relaxation in diastolic heart failure | European Heart Journal | 2009 | 100 |
| 34 | The flavonoid 4,4′-dimethoxychalcone promotes autophagy-dependent longevity across species | Nature Communications | 2019 | 100 |
| 35 | Pathogenic Autoimmunity in Atherosclerosis Evolves From Initially Protective Apolipoprotein B 100 –Reactive CD4 + T-Regulatory Cells | Circulation | 2020 | 100 |
| 36 | EURObservational Research Programme: a worldwide registry on peripartum cardiomyopathy (PPCM) in conjunction with the Heart Failure Association of the European Society of Cardiology Working Group on PPCM | European Journal of Heart Failure | 2014 | 99 |
| 37 | Vitamin D and Cardiovascular Disease | Nutrients | 2013 | 97 |
| 38 | Effects of exercise training on different quality of life dimensions in heart failure with preserved ejection fraction: the Ex-DHF-P trial | European Journal of Preventive Cardiology | 2015 | 85 |
| 39 | Renal Denervation in High-Risk Patients With Hypertension | Journal of the American College of Cardiology | 2020 | 80 |
| 40 | Six-Year Follow-Up of Fractional Flow Reserve-Guided Versus Angiography-Guided Coronary Artery Bypass Graft Surgery | Circulation: Cardiovascular Interventions | 2018 | 79 |
| 41 | Association of physical activity and heart failure with preserved vs. reduced ejection fraction in the elderly: the Framingham Heart Study | European Journal of Heart Failure | 2013 | 78 |
| 42 | Insulin and Hippocampus Activation in Response to Images of High‐Calorie Food in Normal Weight and Obese Adolescents | Obesity | 2010 | 69 |
| 43 | Independence of the blood pressure lowering effect and efficacy of the angiotensin receptor neprilysin inhibitor, LCZ696, in patients with heart failure with preserved ejection fraction: an analysis of the PARAMOUNT trial | European Journal of Heart Failure | 2014 | 67 |
| 44 | Homoarginine in the renal and cardiovascular systems | Amino Acids | 2015 | 64 |
| 45 | NAD + Metabolism in Cardiac Health, Aging, and Disease | Circulation | 2021 | 64 |
| 46 | Dietary spermidine for lowering high blood pressure | Autophagy | 2017 | 63 |
| 47 | Cardiac function during mild hypothermia in pigs: increased inotropy at the expense of diastolic dysfunction | Acta Physiologica | 2010 | 61 |
| 48 | Optimising exercise training in prevention and treatment of diastolic heart failure (OptimEx-CLIN): rationale and design of a prospective, randomised, controlled trial | European Journal of Preventive Cardiology | 2014 | 61 |
| 49 | Quantification of Shear Deformations and Corresponding Stresses in the Biaxially Tested Human Myocardium | Annals of Biomedical Engineering | 2015 | 61 |
| 50 | The slow force response to stretch in atrial and ventricular myocardium from human heart: Functional relevance and subcellular mechanisms | Progress in Biophysics and Molecular Biology | 2008 | 60 |
