| # | Title | Journal | Year | Citations |
|---|
| 1 | Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture | Nature Genetics | 2012 | 1,100 |
| 2 | Independent Association of Low Serum 25-Hydroxyvitamin D and 1,25-Dihydroxyvitamin D Levels With All-Cause and Cardiovascular Mortality | Archives of Internal Medicine | 2008 | 1,027 |
| 3 | Vitamin D deficiency in Europe: pandemic? | American Journal of Clinical Nutrition | 2016 | 963 |
| 4 | Cardioprotection and lifespan extension by the natural polyamine spermidine | Nature Medicine | 2016 | 801 |
| 5 | Vitamin D and Immune Function | Nutrients | 2013 | 743 |
| 6 | Characterization of HULC, a Novel Gene With Striking Up-Regulation in Hepatocellular Carcinoma, as Noncoding RNA | Gastroenterology | 2007 | 725 |
| 7 | Vitamin D deficiency 2.0: an update on the current status worldwide | European Journal of Clinical Nutrition | 2020 | 705 |
| 8 | Bacterial infections in cirrhosis: A position statement based on the EASL Special Conference 2013 | Journal of Hepatology | 2014 | 685 |
| 9 | Vitamin D effects on musculoskeletal health, immunity, autoimmunity, cardiovascular disease, cancer, fertility, pregnancy, dementia and mortality—A review of recent evidence | Autoimmunity Reviews | 2013 | 655 |
| 10 | ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1 | Nature Medicine | 2011 | 612 |
| 11 | Treat-to-target in systemic lupus erythematosus: recommendations from an international task force | Annals of the Rheumatic Diseases | 2014 | 558 |
| 12 | Systemic inflammation in decompensated cirrhosis: Characterization and role in acute‐on‐chronic liver failure | Hepatology | 2016 | 550 |
| 13 | Association of Vitamin D Deficiency with Heart Failure and Sudden Cardiac Death in a Large Cross-Sectional Study of Patients Referred for Coronary Angiography | Journal of Clinical Endocrinology and Metabolism | 2008 | 498 |
| 14 | Shift to Fatty Substrate Utilization in Response to Sodium–Glucose Cotransporter 2 Inhibition in Subjects Without Diabetes and Patients With Type 2 Diabetes | Diabetes | 2016 | 498 |
| 15 | Adipose Triglyceride Lipase Contributes to Cancer-Associated Cachexia | Science | 2011 | 475 |
| 16 | Current vitamin D status in European and Middle East countries and strategies to prevent vitamin D deficiency: a position statement of the European Calcified Tissue Society | European Journal of Endocrinology | 2019 | 443 |
| 17 | Discontinuation of Denosumab therapy for osteoporosis: A systematic review and position statement by ECTS | Bone | 2017 | 373 |
| 18 | The present and future disease burden of hepatitis C virus (HCV) infection with today's treatment paradigm | Journal of Viral Hepatitis | 2014 | 372 |
| 19 | REV-ERBα Participates in Circadian SREBP Signaling and Bile Acid Homeostasis | PLoS Biology | 2009 | 368 |
| 20 | Effect of High-Dose Vitamin D3on Hospital Length of Stay in Critically Ill Patients With Vitamin D Deficiency | JAMA - Journal of the American Medical Association | 2014 | 368 |
| 21 | Frailty and Multimorbidity: A Systematic Review and Meta-analysis | Journals of Gerontology - Series A Biological Sciences and Medical Sciences | 2019 | 354 |
| 22 | Adjuvant endocrine therapy plus zoledronic acid in premenopausal women with early-stage breast cancer: 5-year follow-up of the ABCSG-12 bone-mineral density substudy | Lancet Oncology, The | 2008 | 345 |
| 23 | Continuous subcutaneous insulin infusion versus multiple daily insulin injections in patients with diabetes mellitus: systematic review and meta-analysis | Diabetologia | 2008 | 344 |
| 24 | Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria | PLoS Genetics | 2018 | 341 |
| 25 | Vitamin D status and arterial hypertension: a systematic review | Nature Reviews Cardiology | 2009 | 330 |
| 26 | Predicting distant recurrence in receptor-positive breast cancer patients with limited clinicopathological risk: using the PAM50 Risk of Recurrence score in 1478 postmenopausal patients of the ABCSG-8 trial treated with adjuvant endocrine therapy alone | Annals of Oncology | 2014 | 326 |
| 27 | Klebsiella oxytocaas a Causative Organism of Antibiotic-Associated Hemorrhagic Colitis | New England Journal of Medicine | 2006 | 320 |
| 28 | Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study | Lancet Diabetes and Endocrinology,the | 2014 | 319 |
| 29 | Comparison and validation of simple noninvasive tests for prediction of fibrosis in chronic hepatitis C | Hepatology | 2005 | 310 |
| 30 | MECHANISMS IN ENDOCRINOLOGY: Vitamin D and fertility: a systematic review | European Journal of Endocrinology | 2012 | 301 |
| 31 | Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels | Nature Communications | 2018 | 295 |
| 32 | Assessment of Muscle Function and Physical Performance in Daily Clinical Practice | Calcified Tissue International | 2019 | 295 |
| 33 | COVID-19 Associated Pulmonary Aspergillosis (CAPA)—From Immunology to Treatment | Journal of Fungi (Basel, Switzerland) | 2020 | 292 |
| 34 | A framework for the development of guidelines for the management of glucocorticoid-induced osteoporosis | Osteoporosis International | 2012 | 291 |
| 35 | International consensus conference on stool banking for faecal microbiota transplantation in clinical practice | Gut | 2019 | 290 |
| 36 | Physiological and pathological changes in the redox state of human serum albumin critically influence its binding properties | British Journal of Pharmacology | 2007 | 286 |
| 37 | Effect of Vitamin D Supplementation on Testosterone Levels in Men | Hormone and Metabolic Research | 2011 | 270 |
| 38 | Models for oral uptake of nanoparticles in consumer products | Toxicology | 2012 | 266 |
| 39 | Potential Role of Regulatory T Cells in Reversing Obesity-Linked Insulin Resistance and Diabetic Nephropathy | Diabetes | 2011 | 262 |
| 40 | European Practical and Patient-Centred Guidelines for Adult Obesity Management in Primary Care | Obesity Facts | 2019 | 260 |
| 41 | Women Underrepresented on Editorial Boards of 60 Major Medical Journals | Gender Medicine | 2011 | 258 |
| 42 | Alternate Day Fasting Improves Physiological and Molecular Markers of Aging in Healthy, Non-obese Humans | Cell Metabolism | 2019 | 256 |
| 43 | A Double-Blind, Randomized, Dose-Response Study Investigating the Pharmacodynamic and Pharmacokinetic Properties of the Long-Acting Insulin Analog Detemir | Diabetes Care | 2005 | 254 |
| 44 | Bile Acids as Regulators of Hepatic Lipid and Glucose Metabolism | Digestive Diseases | 2010 | 254 |
| 45 | Long-acting insulin analogues versus NPH insulin (human isophane insulin) for type 2 diabetes mellitus | The Cochrane Library | 2007 | 253 |
| 46 | Alterations in Gut Microbiome Composition and Barrier Function Are Associated with Reproductive and Metabolic Defects in Women with Polycystic Ovary Syndrome (PCOS): A Pilot Study | PLoS ONE | 2017 | 253 |
| 47 | Vitamin D Status and Mortality Risk in CKD: A Meta-analysis of Prospective Studies | American Journal of Kidney Diseases | 2011 | 252 |
| 48 | Vitamin D and cardiovascular disease prevention | Nature Reviews Cardiology | 2016 | 250 |
| 49 | Association of hypovitaminosis D with metabolic disturbances in polycystic ovary syndrome | European Journal of Endocrinology | 2009 | 249 |
| 50 | Rationale and Plan for Vitamin D Food Fortification: A Review and Guidance Paper | Frontiers in Endocrinology | 2018 | 249 |
