(top 60%)
Impact Factor
(top 60%)
extended IF
135(top 2%)
H-Index
325
authors
1.1K
papers
77.4K
citations
4.3K
citing journals
21.9K
citing authors

Most Cited Articles of Pharmacogenetics and Genomics

TitleYearCitations
P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature19962.4K
Human catechol-O-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders19961.5K
The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence1997927
Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants2004765
Cytochrome P450 2C9 polymorphisms: a comprehensive review of the in-vitro and human data2002585
The genetic determinants of the CYP3A5 polymorphism2001557
The role of the CYP2C9-Leu359 allelic variant in the tolbutamide polymorphism1996549
Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver2001503
D2 dopamine receptor gene (DRD2) Taq1 A polymorphism: reduced dopamine D2 receptor binding in the human striatum associated with the A1 allele1997474
Impaired (S)-warfarin metabolism catalysed by the R144C allelic variant of CYP2C91994444
Biochemistry and molecular biology of the human CYP2C subfamily1994436
The AH-receptor: genetics, structure and function1993404
Polymorphisms in human CYP2C8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid2001400
Higher plant metabolism of xenobiotics: the 'green liver' concept1994385
Determination of CYP1A2 and NAT2 phenotypes in human populations by analysis of caffeine urinary metabolites1992380
Phenotyping of drug-metabolizing enzymes in adults: a review of in-vivo cytochrome P450 phenotyping probes2000371
The effect of CYP3A5 and MDR1 (ABCB1) polymorphisms on cyclosporine and tacrolimus dose requirements and trough blood levels in stable renal transplant patients2004368
Noninvasive tests of CYP3A enzymes1994364
High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C, SLCO1B1)2004358
Comprehensive analysis of thiopurine S-methyltransferase phenotype-genotype correlation in a large population of German-Caucasians and identification of novel TPMT variants2004348
Nomenclature for human CYP2D6 alleles1996348
The C3435T mutation in the human MDR1 gene is associated with altered efflux of the P-glycoprotein substrate rhodamine 123 from CD56+ natural killer cells2001341
Sequence diversity and haplotype structure in the human ABCB1 (MDR1, multidrug resistance transporter) gene2003335
MDR1 pharmacogenetics: frequency of the C3435T mutation in exon 26 is significantly influenced by ethnicity2001335
Evaluation of the genetic component of variability in CYP3A4 activity: a repeated drug administration method2000329